This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CCL2 (MCP-1) Monoclonal Antibody (2H5), Biotin, eBioscience
catalog :
13-7096-85
quantity :
500 ug
price :
US 375.00
clonality :
monoclonal
host :
hamsters
conjugate :
biotin
clone name :
2H5

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
flow cytometry
citations: 13
Reference
Pekayvaz K, Gold C, Hoseinpour P, Engel A, Martinez Navarro A, Eivers L, et al. Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation. Immunity. 2023;56:2325-2341.e15 pubmed publisher
Zheng C, Sui B, Zhang X, Hu J, Chen J, Liu J, et al. Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes. J Extracell Vesicles. 2021;10:e12109 pubmed publisher
Li X, Liu R, Wang Y, Zhu W, Zhao D, Wang X, et al. Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions. Cells. 2020;9: pubmed publisher
Haney E, Wu B, Lee K, Hilchie A, Hancock R. Aggregation and Its Influence on the Immunomodulatory Activity of Synthetic Innate Defense Regulator Peptides. Cell Chem Biol. 2017;24:969-980.e4 pubmed publisher
Valera E, McClellan M, Bailey R. Magnetically-actuated, bead-enhanced silicon photonic immunosensor. Anal Methods. 2015;7:8539-8544 pubmed
Valera E, Shia W, Bailey R. Development and validation of an immunosensor for monocyte chemotactic protein 1 using a silicon photonic microring resonator biosensing platform. Clin Biochem. 2016;49:121-6 pubmed publisher
Shen C, Lie P, Miao T, Yu M, Lu Q, Feng T, et al. Conditioned medium from umbilical cord mesenchymal stem cells induces migration and angiogenesis. Mol Med Rep. 2015;12:20-30 pubmed publisher
Bekkering S, Quintin J, Joosten L, Van der Meer J, Netea M, Riksen N. Oxidized low-density lipoprotein induces long-term proinflammatory cytokine production and foam cell formation via epigenetic reprogramming of monocytes. Arterioscler Thromb Vasc Biol. 2014;34:1731-8 pubmed publisher
Namjoshi D, Martin G, Donkin J, Wilkinson A, Stukas S, Fan J, et al. The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. PLoS ONE. 2013;8:e53529 pubmed publisher
van Helden M, Zaiss D, Sijts A. CCR2 defines a distinct population of NK cells and mediates their migration during influenza virus infection in mice. PLoS ONE. 2012;7:e52027 pubmed publisher
Lehar J, Krueger A, Avery W, Heilbut A, Johansen L, Price E, et al. Synergistic drug combinations tend to improve therapeutically relevant selectivity. Nat Biotechnol. 2009;27:659-66 pubmed publisher
Taal M, Chertow G, Rennke H, Gurnani A, Jiang T, Shahsafaei A, et al. Mechanisms underlying renoprotection during renin-angiotensin system blockade. Am J Physiol Renal Physiol. 2001;280:F343-55 pubmed
Luo Y, Fischer F, Hancock W, Dorf M. Macrophage inflammatory protein-2 and KC induce chemokine production by mouse astrocytes. J Immunol. 2000;165:4015-23 pubmed
product information
Product Type :
Antibody
Product Name :
CCL2 (MCP-1) Monoclonal Antibody (2H5), Biotin, eBioscience
Catalog # :
13-7096-85
Quantity :
500 ug
Price :
US 375.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Armenian Hamster
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: 0.5-2 ug/mL, Flow Cytometry: Assay-dependent
Species :
Human, Mouse, Rat
Clone :
2H5
Isotype :
IgG
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.5-2 ug/mL, Flow Cytometry: Assay-dependent
Aliases :
Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA