Phosphotyrosine Antibody Cocktail, HRP | Invitrogen 13-6620 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phosphotyrosine Antibody Cocktail, HRP

catalog :

13-6620

quantity :

100 µg

price :

US 400

clonality :

monoclonal

host :

mouse

conjugate :

HRP

clone name :

PY-7E1, PY20

application :

western blot

citations: 3

Reference
Bahl S, Ling H, Acharige N, Santos Barriopedro I, Pflum M, Seto E. EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function. Cell Death Dis. 2021;12:469 pubmed publisher
Alvarez Errico D, Sayos J, Lopez Botet M. The IREM-1 (CD300f) inhibitory receptor associates with the p85alpha subunit of phosphoinositide 3-kinase. J Immunol. 2007;178:808-16 pubmed
Del Valle J, Engel P, Martin M. The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2). J Biol Chem. 2003;278:17430-7 pubmed

product information

Product Type :

Antibody

Product Name :

Phosphotyrosine Antibody Cocktail, HRP

Catalog # :

13-6620

Quantity :

100 µg

Price :

US 400

Clonality :

Cocktail

Purity :

purified

Host :

Mouse

Reactivity :

Chemical

Applications :

Western Blot: 1:500-1:1,000

Species :

Chemical

Clone :

PY-7E1, PY20

Isotype :

IgG1/IgG2b

Storage :

4° C

Description :

The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The fluorescein (FITC) conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.

Immunogen :

Tyrosine-phosphorylated proteins.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:1,000

Aliases :

Phosphotyrosine; pTyr; pY