MAdCAM1 Monoclonal Antibody (MECA-367), Biotin, eBioscience | Invitrogen 13-5997-85 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MAdCAM1 Monoclonal Antibody (MECA-367), Biotin, eBioscience

catalog :

13-5997-85

quantity :

500 µg

price :

US 341

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

MECA-367

reactivity :

mouse

application :

immunohistochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; fig 1	Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
	Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, et al. A TNF-?-CCL20-CCR6 axis regulates Nod1-induced B cell responses. J Immunol. 2014;192:2787-99 pubmed publisher
	Smigiel K, Richards E, Srivastava S, Thomas K, Dudda J, Klonowski K, et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med. 2014;211:121-36 pubmed publisher
	Mok Y, Schwierzeck V, Thomas D, Vigorito E, Rayner T, Jarvis L, et al. MiR-210 is induced by Oct-2, regulates B cells, and inhibits autoantibody production. J Immunol. 2013;191:3037-3048 pubmed publisher
	Tlaxca J, Rychak J, Ernst P, Konkalmatt P, Shevchenko T, Pizarro T, et al. Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease. J Control Release. 2013;165:216-25 pubmed publisher
	Hindley J, Jones E, Smart K, Bridgeman H, Lauder S, Ondondo B, et al. T-cell trafficking facilitated by high endothelial venules is required for tumor control after regulatory T-cell depletion. Cancer Res. 2012;72:5473-82 pubmed publisher
	Satpathy A, Kc W, Albring J, Edelson B, Kretzer N, Bhattacharya D, et al. Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages. J Exp Med. 2012;209:1135-52 pubmed publisher
	Guerra F, Gommerman J, Corfe S, Paige C, Rottapel R. Homeodomain-interacting protein kinase (HIPK)-1 is required for splenic B cell homeostasis and optimal T-independent type 2 humoral response. PLoS ONE. 2012;7:e35533 pubmed publisher
	Subramanian H, Grailer J, Ohlrich K, Rymaszewski A, Loppnow J, Kodera M, et al. Signaling through L-selectin mediates enhanced chemotaxis of lymphocyte subsets to secondary lymphoid tissue chemokine. J Immunol. 2012;188:3223-36 pubmed publisher
	Bénézech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, et al. Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010;184:4521-30 pubmed publisher
	Glanville S, Bekiaris V, Jenkinson E, Lane P, Anderson G, Withers D. Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization. Eur J Immunol. 2009;39:280-9 pubmed publisher
	Withers D, Kim M, Bekiaris V, Rossi S, Jenkinson W, Gaspal F, et al. The role of lymphoid tissue inducer cells in splenic white pulp development. Eur J Immunol. 2007;37:3240-5 pubmed
	Chen G, Dimitriou I, La Rose J, Ilangumaran S, Yeh W, Doody G, et al. The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response. Mol Cell Biol. 2007;27:3109-22 pubmed
	Wen L, Shinton S, Hardy R, Hayakawa K. Association of B-1 B cells with follicular dendritic cells in spleen. J Immunol. 2005;174:6918-26 pubmed
	Streeter P, Berg E, Rouse B, Bargatze R, Butcher E. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature. 1988;331:41-6 pubmed
	Streeter P, Rouse B, Butcher E. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J Cell Biol. 1988;107:1853-62 pubmed

product information

Product Type :

Antibody

Product Name :

MAdCAM1 Monoclonal Antibody (MECA-367), Biotin, eBioscience

Catalog # :

13-5997-85

Quantity :

500 µg

Pricing :

US 341

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Mouse

Clone :

MECA-367

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

AV211525; hMAdCAM-1; MACAM1; MADCAM1; MAdCAM-1; mMAdCAM-1; mucosal addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule-1; mucosal vascular addressin cell adhesion molecule 1; rMAdCAM-1

more info or order :

Invitrogen product webpage