This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IgE Monoclonal Antibody (23G3), Biotin, eBioscience
catalog :
13-5992-81
quantity :
50 ug
price :
US 134.00
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
23G3
application :
flow cytometry
citations: 24
Reference
Brishti A, Germundson Hermanson D, Smith N, Kearney A, Warda Y, Nagamoto Combs K. Asymptomatic sensitization to a cow's milk protein induces sustained neuroinflammation and behavioral changes with chronic allergen exposure. Front Allergy. 2022;3:870628 pubmed publisher
Smith N, Germundson D, Combs C, Vendsel L, Nagamoto Combs K. Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy. Front Cell Neurosci. 2019;13:320 pubmed publisher
Esterházy D, Canesso M, Mesin L, Muller P, de Castro T, Lockhart A, et al. Compartmentalized gut lymph node drainage dictates adaptive immune responses. Nature. 2019;569:126-130 pubmed publisher
Xia F, Deng C, Jiang Y, Qu Y, Deng J, Cai Z, et al. IL4 (interleukin 4) induces autophagy in B cells leading to exacerbated asthma. Autophagy. 2018;14:450-464 pubmed publisher
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
Srikakulapu P, Hu D, Yin C, Mohanta S, Bontha S, Peng L, et al. Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice. Arterioscler Thromb Vasc Biol. 2016;36:1174-85 pubmed publisher
Reber L, Marichal T, Sokolove J, Starkl P, Gaudenzio N, Iwakura Y, et al. Contribution of mast cell-derived interleukin-1? to uric acid crystal-induced acute arthritis in mice. Arthritis Rheumatol. 2014;66:2881-91 pubmed publisher
Hwang Y, Yun M, Jeong K, Park J. Uremic toxin indoxyl 3-sulfate regulates the differentiation of Th2 but not of Th1 cells to lessen allergic asthma. Toxicol Lett. 2014;225:130-8 pubmed publisher
Metcalf D, Ng A, Baldwin T, Di Rago L, Mifsud S. Concordant mast cell and basophil production by individual hematopoietic blast colony-forming cells. Proc Natl Acad Sci U S A. 2013;110:9031-5 pubmed publisher
Burton O, Darling A, Zhou J, Noval Rivas M, Jones T, Gurish M, et al. Direct effects of IL-4 on mast cells drive their intestinal expansion and increase susceptibility to anaphylaxis in a murine model of food allergy. Mucosal Immunol. 2013;6:740-50 pubmed publisher
Song Y, Qu C, Srivastava K, Yang N, Busse P, Zhao W, et al. Food allergy herbal formula 2 protection against peanut anaphylactic reaction is via inhibition of mast cells and basophils. J Allergy Clin Immunol. 2010;126:1208-17.e3 pubmed publisher
Cheng L, Wang Z, Locksley R. Murine B cells regulate serum IgE levels in a CD23-dependent manner. J Immunol. 2010;185:5040-7 pubmed publisher
Kim H, Lee D, Lee S, Seong A, Gin D, Hwang J, et al. Chlorogenic acid suppresses pulmonary eosinophilia, IgE production, and Th2-type cytokine production in an ovalbumin-induced allergic asthma: activation of STAT-6 and JNK is inhibited by chlorogenic acid. Int Immunopharmacol. 2010;10:1242-8 pubmed publisher
Ota T, Aoki Ota M, Duong B, Nemazee D. Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE. J Immunol. 2009;182:8110-7 pubmed publisher
Khramova D, Popov S, Golovchenko V, Vityazev F, Paderin N, Ovodov Y. Abrogation of the oral tolerance to ovalbumin in mice by citrus pectin. Nutrition. 2009;25:226-32 pubmed publisher
Sadri N, Schneider R. Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease. J Invest Dermatol. 2009;129:657-70 pubmed publisher
Ryzhov S, Zaynagetdinov R, Goldstein A, Novitskiy S, Dikov M, Blackburn M, et al. Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells. J Immunol. 2008;180:7212-20 pubmed
Mori T, Kabashima K, Yoshiki R, Sugita K, Shiraishi N, Onoue A, et al. Cutaneous hypersensitivities to hapten are controlled by IFN-gamma-upregulated keratinocyte Th1 chemokines and IFN-gamma-downregulated langerhans cell Th2 chemokines. J Invest Dermatol. 2008;128:1719-27 pubmed publisher
Nagata T, Toyota T, Ishigaki H, Ichihashi T, Kajino K, Kashima Y, et al. Peptides coupled to the surface of a kind of liposome protect infection of influenza viruses. Vaccine. 2007;25:4914-21 pubmed
Taketomi Y, Sunaga K, Tanaka S, Nakamura M, Arata S, Okuda T, et al. Impaired mast cell maturation and degranulation and attenuated allergic responses in Ndrg1-deficient mice. J Immunol. 2007;178:7042-53 pubmed
Obata K, Mukai K, Tsujimura Y, Ishiwata K, Kawano Y, Minegishi Y, et al. Basophils are essential initiators of a novel type of chronic allergic inflammation. Blood. 2007;110:913-20 pubmed
Popov S, Golovchenko V, Ovodova R, Smirnov V, Khramova D, Popova G, et al. Characterisation of the oral adjuvant effect of lemnan, a pectic polysaccharide of Lemna minor L. Vaccine. 2006;24:5413-9 pubmed
Popov S, Günter E, Markov P, Smirnov V, Khramova D, Ovodov Y. Adjuvant effect of lemnan, pectic polysaccharide of callus culture of Lemna minor L. at oral administration. Immunopharmacol Immunotoxicol. 2006;28:141-52 pubmed
Keegan A, Fratazzi C, Shopes B, Baird B, Conrad D. Characterization of new rat anti-mouse IgE monoclonals and their use along with chimeric IgE to further define the site that interacts with Fc epsilon RII and Fc epsilon RI. Mol Immunol. 1991;28:1149-54 pubmed
product information
Product Type :
Antibody
Product Name :
IgE Monoclonal Antibody (23G3), Biotin, eBioscience
Catalog # :
13-5992-81
Quantity :
50 ug
Price :
US 134.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
ELISA: 1:5,000-1:10,000, Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
23G3
Isotype :
IgG1, kappa
Storage :
4 C, do not freeze
Description :
IgE is one of the five classes of immunoglobulins found in mammals. Monomers consist of two heavy (epsilon) chains with 4 Ig-like constant domains, and two light chains. IgE plays an essential role in type I hypersensitivity (allergic responses such as hay fever, asthma, hives, anaphylatic shock) by binding to Fc receptors on basophils and mast cells. Crosslinking of IgE bound to Fc receptors induces degranulation of mast cells and basophils that promote allergic manifestations. IgE is also functionally important for immunity against parasites.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:5,000-1:10,000, Flow Cytometry: 0.25 ug/test
Aliases :
Gm900; Ighe; Immunoglobulin E; Immunoglobulin heavy constant epsilon; ImmunoglobulinE
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA