Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience | Invitrogen 13-5991-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience

catalog :

13-5991-82

quantity :

100 µg

price :

US 171

clonality :

monoclonal

host :

Syrian golden hamster

conjugate :

biotin

clone name :

14B11

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3	Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
	McFall E, Tu M, Al Khattabi N, Tai L, St Laurent A, Tzankova V, et al. Optimized tetramer analysis reveals Ly49 promiscuity for MHC ligands. J Immunol. 2013;191:5722-9 pubmed publisher
	Trotta R, Chen L, Costinean S, Josyula S, Mundy Bosse B, Ciarlariello D, et al. Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells. Blood. 2013;121:3126-34 pubmed publisher
	Baird J, Byrne K, Lizotte P, Toraya Brown S, Scarlett U, Alexander M, et al. Immune-mediated regression of established B16F10 melanoma by intratumoral injection of attenuated Toxoplasma gondii protects against rechallenge. J Immunol. 2013;190:469-78 pubmed publisher
	Notake T, Horisawa S, Sanjo H, Miyagawa S, Hida S, Taki S. Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors. J Immunol. 2012;188:4838-45 pubmed publisher
	Wu X, Chen Y, Wei H, Sun R, Tian Z. Development of murine hepatic NK cells during ontogeny: comparison with spleen NK cells. Clin Dev Immunol. 2012;2012:759765 pubmed publisher
	Vargas C, Poursine Laurent J, Yang L, Yokoyama W. Development of thymic NK cells from double negative 1 thymocyte precursors. Blood. 2011;118:3570-8 pubmed publisher
	Pyzik M, Charbonneau B, Gendron Pontbriand E, Babic M, Krmpotic A, Jonjic S, et al. Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. J Exp Med. 2011;208:1105-17 pubmed publisher
	Hasenberg M, Köhler A, Bonifatius S, Borucki K, Riek Burchardt M, Achilles J, et al. Rapid immunomagnetic negative enrichment of neutrophil granulocytes from murine bone marrow for functional studies in vitro and in vivo. PLoS ONE. 2011;6:e17314 pubmed publisher
	Croy B, Zhang J, Tayade C, Colucci F, Yadi H, Yamada A. Analysis of uterine natural killer cells in mice. Methods Mol Biol. 2010;612:465-503 pubmed publisher
	Yu J, Wei M, Mao H, Zhang J, Hughes T, Mitsui T, et al. CD94 defines phenotypically and functionally distinct mouse NK cell subsets. J Immunol. 2009;183:4968-74 pubmed publisher
	Xie X, Stadnisky M, Brown M. MHC class I Dk locus and Ly49G2+ NK cells confer H-2k resistance to murine cytomegalovirus. J Immunol. 2009;182:7163-71 pubmed publisher
	French J, Roark C, Born W, O Brien R. Gammadelta T lymphocyte homeostasis is negatively regulated by beta2-microglobulin. J Immunol. 2009;182:1892-900 pubmed publisher
	Coles M, McMahon C, Takizawa H, Raulet D. Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors. Eur J Immunol. 2000;30:236-44 pubmed
	Corral L, Takizawa H, Hanke T, Jamieson A, Raulet D. A new monoclonal antibody reactive with several Ly49 NK cell receptors mediates redirected lysis of target cells. Hybridoma. 1999;18:359-66 pubmed

product information

Product Type :

Antibody

Product Name :

Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience

Catalog # :

13-5991-82

Quantity :

100 µg

Price :

US 171

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Syrian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

14B11

Isotype :

IgG

Storage :

4° C, do not freeze

Description :

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

5E6; Cmv1; Cmv-1; cytomegalovirus resistance 1; killer cell lectin-like receptor 3; Killer cell lectin-like receptor 6; killer cell lectin-like receptor 8; killer cell lectin-like receptor, subfamily A, member 3; killer cell lectin-like receptor, subfamily A, member 6; killer cell lectin-like receptor, subfamily A, member 8; Klra3; Klra6; Klra8; Ly49C; Ly-49c; Ly49f; ly-49f; Ly49-f; Ly49H; Ly-49h; Ly49-h; Ly49u ; Lymphocyte antigen 49c; lymphocyte antigen 49f; Lymphocyte antigen 49h; natural killer cell-associated antigen 2; Nk2; Nk-2; Nk2.1; NK-2.1; T-cell surface glycoprotein Ly-49C; T-cell surface glycoprotein Ly-49F; T-cell surface glycoprotein Ly-49H

more info or order :

Invitrogen product webpage