Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience™ | Invitrogen 13-5991-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience™

catalog :

13-5991-81

quantity :

50 µg

price :

US 309.00

clonality :

monoclonal

host :

Syrian golden hamster

conjugate :

biotin

clone name :

14B11

reactivity :

mouse

application :

flow cytometry

citations: 4

Reference
Notake T, Horisawa S, Sanjo H, Miyagawa S, Hida S, Taki S. Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors. J Immunol. 2012;188:4838-45 pubmed publisher
Pyzik M, Charbonneau B, Gendron Pontbriand E, Babic M, Krmpotic A, Jonjic S, et al. Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strains. J Exp Med. 2011;208:1105-17 pubmed publisher
Hasenberg M, Köhler A, Bonifatius S, Borucki K, Riek Burchardt M, Achilles J, et al. Rapid immunomagnetic negative enrichment of neutrophil granulocytes from murine bone marrow for functional studies in vitro and in vivo. PLoS ONE. 2011;6:e17314 pubmed publisher
Xie X, Stadnisky M, Brown M. MHC class I Dk locus and Ly49G2+ NK cells confer H-2k resistance to murine cytomegalovirus. J Immunol. 2009;182:7163-71 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Ly-49C/I/F/H Monoclonal Antibody (14B11), Biotin, eBioscience™

Catalog # :

13-5991-81

Quantity :

50 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Syrian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

14B11

Isotype :

IgG

Storage :

4° C, do not freeze

Description :

KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

5E6; Cmv1; Cmv-1; cytomegalovirus resistance 1; killer cell lectin-like receptor 3; Killer cell lectin-like receptor 6; killer cell lectin-like receptor 8; killer cell lectin-like receptor, subfamily A, member 3; killer cell lectin-like receptor, subfamily A, member 6; killer cell lectin-like receptor, subfamily A, member 8; Klra3; Klra6; Klra8; Ly49C; Ly-49c; Ly49f; Ly-49f; Ly49-f; Ly49H; ly-49h; Ly49-h; Ly49u ; Lymphocyte antigen 49c; lymphocyte antigen 49f; Lymphocyte antigen 49h; natural killer cell-associated antigen 2; Nk2; Nk-2; Nk2.1; NK-2.1; T-cell surface glycoprotein Ly-49C; T-cell surface glycoprotein Ly-49F; T-cell surface glycoprotein Ly-49H