This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
AID Monoclonal Antibody (mAID-2), Biotin, eBioscience
catalog :
13-5959-82
quantity :
100 ug
price :
US 451.00
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
mAID-2

The same clone is also sold as:
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 7
Reference
Delgado P, xc1 lvarez Prado x, Marina Z xe1 rate E, Sernández I, Mur S, de la Barrera J, et al. Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma. PLoS Genet. 2020;16:e1008960 pubmed publisher
Marina Zárate E, Pérez García A, Ramiro A. CCCTC-Binding Factor Locks Premature IgH Germline Transcription and Restrains Class Switch Recombination. Front Immunol. 2017;8:1076 pubmed publisher
Compagno M, Wang Q, Pighi C, Cheong T, Meng F, Poggio T, et al. Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells. Nature. 2017;542:489-493 pubmed publisher
Marasco E, Farroni C, Cascioli S, Marcellini V, Scarsella M, Giorda E, et al. B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients. Eur J Immunol. 2017;47:131-143 pubmed publisher
Montamat Sicotte D, Litzler L, Abreu C, Safavi S, Zahn A, Orthwein A, et al. HSP90 inhibitors decrease AID levels and activity in mice and in human cells. Eur J Immunol. 2015;45:2365-76 pubmed publisher
Liang G, Liu G, Kitamura K, Wang Z, Chowdhury S, Monjurul A, et al. TGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex. PLoS Pathog. 2015;11:e1004780 pubmed publisher
Tsuji M, Suzuki K, Kitamura H, Maruya M, Kinoshita K, Ivanov I, et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity. 2008;29:261-71 pubmed publisher
product information
Product Type :
Antibody
Product Name :
AID Monoclonal Antibody (mAID-2), Biotin, eBioscience
Catalog # :
13-5959-82
Quantity :
100 ug
Price :
US 451.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Western Blot: Assay-Dependent
Species :
Human, Mouse
Clone :
mAID-2
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Frozen): 20 ug/mL, Immunohistochemistry (Paraffin): 20 ug/mL, Western Blot: Assay-Dependent
Aliases :
activation induced deaminase; activation-induced cytidine deaminase; Aicda; AID; Arp2; CDA2; Cytidine aminohydrolase; epididymis secretory protein Li 284; HEL-S-284; HIGM2; integrated into Burkitt's lymphoma cell line Ramos; single-stranded DNA cytosine deaminase
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA