product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NK1.1 Monoclonal Antibody (PK136), Biotin, eBioscience™
catalog :
13-5941-85
quantity :
500 µg
price :
US 309.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
PK136
reactivity :
mouse
application :
flow cytometry, other
more info or order :
citations: 289
Published Application/Species/Sample/DilutionReference
  • other; mouse; loading ...; fig 2b
Leach S, Shinnakasu R, Adachi Y, Momota M, Makino Okamura C, Yamamoto T, et al. Requirement for memory B cell activation in protection from heterologous influenza virus reinfection. Int Immunol. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Kaminsky L, Sei J, Parekh N, Davies M, Reider I, Krouse T, et al. Redundant Function of Plasmacytoid and Conventional Dendritic Cells Is Required To Survive a Natural Virus Infection. J Virol. 2015;89:9974-85 pubmed publisher
  • flow cytometry; mouse
Schwartz C, Turqueti Neves A, Hartmann S, Yu P, Nimmerjahn F, Voehringer D. Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc Natl Acad Sci U S A. 2014;111:E5169-77 pubmed publisher
Zhang X, Feng J, Chen S, Yang H, Dong Z. Synergized regulation of NK cell education by NKG2A and specific Ly49 family members. Nat Commun. 2019;10:5010 pubmed publisher
Hayashi Y, Goyama S, Liu X, Tamura M, Asada S, Tanaka Y, et al. Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia. Nat Commun. 2019;10:4869 pubmed publisher
Huang A, Shinde P, Huang J, Senff T, Xu H, Margotta C, et al. Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells. JCI Insight. 2019;4: pubmed publisher
Teo T, Lum F, Ghaffar K, Chan Y, Amrun S, Tan J, et al. Plasmodium co-infection protects against chikungunya virus-induced pathologies. Nat Commun. 2018;9:3905 pubmed publisher
Yi S, Zhai J, Niu R, Zhu G, Wang M, Liu J, et al. Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge. Nat Commun. 2018;9:3879 pubmed publisher
Xu C, Lu X, Liu W, Chen A, Meng G, Zhang H, et al. CD8+ T cells mediate the antitumor activity of frankincense and myrrh in hepatocellular carcinoma. J Transl Med. 2018;16:132 pubmed publisher
Krzywinska E, Kantari Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, et al. Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis. Nat Commun. 2017;8:1597 pubmed publisher
Gao W, Li F, Zhou Z, Xu X, Wu Y, Zhou S, et al. IL-2/Anti-IL-2 Complex Attenuates Inflammation and BBB Disruption in Mice Subjected to Traumatic Brain Injury. Front Neurol. 2017;8:281 pubmed publisher
Audzevich T, Bashford Rogers R, Mabbott N, Frampton D, Freeman T, Potocnik A, et al. Pre/pro-B cells generate macrophage populations during homeostasis and inflammation. Proc Natl Acad Sci U S A. 2017;114:E3954-E3963 pubmed publisher
Aguilar O, Berry R, Rahim M, Reichel J, Popovic B, Tanaka M, et al. A Viral Immunoevasin Controls Innate Immunity by Targeting the Prototypical Natural Killer Cell Receptor Family. Cell. 2017;169:58-71.e14 pubmed publisher
Pandya H, Shen M, Ichikawa D, Sedlock A, Choi Y, Johnson K, et al. Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nat Neurosci. 2017;20:753-759 pubmed publisher
Sklarz T, Guan P, Gohil M, Cotton R, Ge M, Haczku A, et al. mTORC2 regulates multiple aspects of NKT-cell development and function. Eur J Immunol. 2017;47:516-526 pubmed publisher
Cheadle E, Lipowska Bhalla G, Dovedi S, Fagnano E, Klein C, Honeychurch J, et al. A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells. Leukemia. 2017;31:1611-1621 pubmed publisher
Yang M, Chen S, Du J, He J, Wang Y, Li Z, et al. NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation. Nat Commun. 2016;7:12730 pubmed publisher
Vannella K, Ramalingam T, Hart K, de Queiroz Prado R, Sciurba J, Barron L, et al. Acidic chitinase primes the protective immune response to gastrointestinal nematodes. Nat Immunol. 2016;17:538-44 pubmed publisher
Bravo B, Gallego M, Flores A, Bornstein R, Puente Bedia A, Hernandez J, et al. Restrained Th17 response and myeloid cell infiltration into the central nervous system by human decidua-derived mesenchymal stem cells during experimental autoimmune encephalomyelitis. Stem Cell Res Ther. 2016;7:43 pubmed publisher
Ye Y, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz G, et al. Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis. Circ Res. 2015;117:835-45 pubmed publisher
Krneta T, Gillgrass A, Chew M, Ashkar A. The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol. 2016;13:628-39 pubmed publisher
Wu J, Waxman D. Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8+ T-cell responses and immune memory. Oncoimmunology. 2015;4:e1005521 pubmed
Tähtinen S, Kaikkonen S, Merisalo Soikkeli M, Grönberg Vähä Koskela S, Kanerva A, Parviainen S, et al. Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors. PLoS ONE. 2015;10:e0131242 pubmed publisher
Zhang J, Han C, Dai H, Hou J, Dong Y, Cui X, et al. Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury. J Am Soc Nephrol. 2016;27:92-106 pubmed publisher
Habbeddine M, Verbeke P, Karaz S, Bobé P, Kanellopoulos Langevin C. Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface. PLoS ONE. 2014;9:e107267 pubmed publisher
Geem D, Medina Contreras O, McBride M, Newberry R, Koni P, Denning T. Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes. J Immunol. 2014;193:431-8 pubmed publisher
Guo H, Ma O, Friedman A. The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells. J Leukoc Biol. 2014;96:419-26 pubmed publisher
Mahmud S, Manlove L, Schmitz H, Xing Y, Wang Y, Owen D, et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat Immunol. 2014;15:473-81 pubmed publisher
Yamamoto H, Nakamura Y, Sato K, Takahashi Y, Nomura T, Miyasaka T, et al. Defect of CARD9 leads to impaired accumulation of gamma interferon-producing memory phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans. Infect Immun. 2014;82:1606-15 pubmed publisher
Han Y, Ling M, Mao H, Zheng J, Liu M, Lam K, et al. Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice. PLoS ONE. 2014;9:e86166 pubmed publisher
Ribes S, Meister T, Ott M, Redlich S, Janova H, Hanisch U, et al. Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection. J Neuroinflammation. 2014;11:14 pubmed publisher
Leigh N, Bian G, Ding X, Liu H, Aygun Sunar S, Burdelya L, et al. A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity. PLoS ONE. 2014;9:e85587 pubmed publisher
Webster K, Kim H, Kyparissoudis K, Corpuz T, Pinget G, Uldrich A, et al. IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival. Mucosal Immunol. 2014;7:1058-67 pubmed publisher
Grinenko T, Arndt K, Portz M, Mende N, Günther M, Cosgun K, et al. Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med. 2014;211:209-15 pubmed publisher
Spees A, Kingsbury D, Wangdi T, Xavier M, Tsolis R, BAUMLER A. Neutrophils are a source of gamma interferon during acute Salmonella enterica serovar Typhimurium colitis. Infect Immun. 2014;82:1692-7 pubmed publisher
Wegorzewska M, Nijagal A, Wong C, Le T, Lescano N, Tang Q, et al. Fetal intervention increases maternal T cell awareness of the foreign conceptus and can lead to immune-mediated fetal demise. J Immunol. 2014;192:1938-45 pubmed publisher
Litwak S, Payne N, Campanale N, Ozturk E, Lee J, Petratos S, et al. Nogo-receptor 1 deficiency has no influence on immune cell repertoire or function during experimental autoimmune encephalomyelitis. PLoS ONE. 2013;8:e82101 pubmed publisher
Murphy K, Erickson J, Johnson C, Seiler C, Bedi J, Hu P, et al. CD8+ T cell-independent tumor regression induced by Fc-OX40L and therapeutic vaccination in a mouse model of glioma. J Immunol. 2014;192:224-33 pubmed publisher
Farhadi N, Lambert L, Triulzi C, Openshaw P, Guerra N, Culley F. Natural killer cell NKG2D and granzyme B are critical for allergic pulmonary inflammation. J Allergy Clin Immunol. 2014;133:827-35.e3 pubmed publisher
Vom Berg J, Vrohlings M, Haller S, Haimovici A, Kulig P, Sledzińska A, et al. Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection. J Exp Med. 2013;210:2803-11 pubmed publisher
Rissiek B, Danquah W, Haag F, Koch Nolte F. Technical Advance: a new cell preparation strategy that greatly improves the yield of vital and functional Tregs and NKT cells. J Leukoc Biol. 2014;95:543-9 pubmed publisher
Hams E, Locksley R, McKenzie A, Fallon P. Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice. J Immunol. 2013;191:5349-53 pubmed publisher
Baccarella A, Fontana M, Chen E, Kim C. Toll-like receptor 7 mediates early innate immune responses to malaria. Infect Immun. 2013;81:4431-42 pubmed publisher
Thomas L, Peterson M, Long E. Cutting edge: NK cell licensing modulates adhesion to target cells. J Immunol. 2013;191:3981-5 pubmed publisher
Sharma A, Berga Bolaños R, Sultana D, Sen J. IL-4 and IL-4 receptor expression is dispensable for the development and function of natural killer T cells. PLoS ONE. 2013;8:e71872 pubmed publisher
Grishkan I, Ntranos A, Calabresi P, Gocke A. Helper T cells down-regulate CD4 expression upon chronic stimulation giving rise to double-negative T cells. Cell Immunol. 2013;284:68-74 pubmed publisher
Guo Y, Sun X, Shibata K, Yamada H, Muta H, Podack E, et al. CD30 is required for activation of a unique subset of interleukin-17A-producing ?? T cells in innate immunity against Mycobacterium bovis Bacillus Calmette-Guerin infection. Infect Immun. 2013;81:3923-34 pubmed publisher
Huang H, Chen H, Evankovich J, Yan W, Rosborough B, Nace G, et al. Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury. J Immunol. 2013;191:2665-79 pubmed publisher
Patnode M, Cheng C, Chou C, Singer M, Elin M, Uchimura K, et al. Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue. J Biol Chem. 2013;288:26533-45 pubmed publisher
Takigawa T, Miyazaki H, Kinoshita M, Kawarabayashi N, Nishiyama K, Hatsuse K, et al. Glucocorticoid receptor-dependent immunomodulatory effect of ursodeoxycholic acid on liver lymphocytes in mice. Am J Physiol Gastrointest Liver Physiol. 2013;305:G427-38 pubmed publisher
Bonito A, Aloman C, Fiel M, Danzl N, Cha S, Weinstein E, et al. Medullary thymic epithelial cell depletion leads to autoimmune hepatitis. J Clin Invest. 2013;123:3510-24 pubmed publisher
Turner M, Lamorte M, Chretien N, Havari E, Roberts B, Kaplan J, et al. Immune status following alemtuzumab treatment in human CD52 transgenic mice. J Neuroimmunol. 2013;261:29-36 pubmed publisher
Baird J, Fox B, Sanders K, Lizotte P, Cubillos Ruiz J, Scarlett U, et al. Avirulent Toxoplasma gondii generates therapeutic antitumor immunity by reversing immunosuppression in the ovarian cancer microenvironment. Cancer Res. 2013;73:3842-51 pubmed publisher
Gao Y, Li Z, Hassan N, Mehta P, Burns A, Tang X, et al. NK cells are necessary for recovery of corneal CD11c+ dendritic cells after epithelial abrasion injury. J Leukoc Biol. 2013;94:343-51 pubmed publisher
Shitara S, Hara T, Liang B, Wagatsuma K, Zuklys S, Hollander G, et al. IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCR??+ intraepithelial lymphocytes. J Immunol. 2013;190:6173-9 pubmed publisher
Singh R, Franke K, Kalucka J, Mamlouk S, Muschter A, Gembarska A, et al. HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress. Blood. 2013;121:5158-66 pubmed publisher
Sheppard S, Triulzi C, Ardolino M, Serna D, Zhang L, Raulet D, et al. Characterization of a novel NKG2D and NKp46 double-mutant mouse reveals subtle variations in the NK cell repertoire. Blood. 2013;121:5025-33 pubmed publisher
Liu R, Engels B, Schreiber K, Ciszewski C, Schietinger A, Schreiber H, et al. IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner. Proc Natl Acad Sci U S A. 2013;110:8158-63 pubmed publisher
Doyle A, Jacobsen E, Ochkur S, Willetts L, Shim K, Neely J, et al. Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing Cre recombinase exclusively in eosinophils. J Leukoc Biol. 2013;94:17-24 pubmed publisher
Gerber S, Sedlacek A, Cron K, Murphy S, Frelinger J, Lord E. IFN-γ mediates the antitumor effects of radiation therapy in a murine colon tumor. Am J Pathol. 2013;182:2345-54 pubmed publisher
Eissler N, Mysliwietz J, Deppisch N, Ruf P, Lindhofer H, Mocikat R. Potential of the trifunctional bispecific antibody surek depends on dendritic cells: rationale for a new approach of tumor immunotherapy. Mol Med. 2013;19:54-61 pubmed publisher
Lee A, Kandiah N, Karimi K, Clark D, Ashkar A. Interleukin-15 is required for maximal lipopolysaccharide-induced abortion. J Leukoc Biol. 2013;93:905-12 pubmed publisher
Lewis N, Haxhinasto S, Anderson S, Stefanopoulos D, Fogal S, Adusumalli P, et al. Circulating monocytes are reduced by sphingosine-1-phosphate receptor modulators independently of S1P3. J Immunol. 2013;190:3533-40 pubmed publisher
Ohashi T, Akazawa T, Aoki M, Kuze B, Mizuta K, Ito Y, et al. Dichloroacetate improves immune dysfunction caused by tumor-secreted lactic acid and increases antitumor immunoreactivity. Int J Cancer. 2013;133:1107-18 pubmed publisher
Ma S, Richardson J, BitMansour A, Solberg T, Pidikiti R, Song K, et al. Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation. PLoS ONE. 2013;8:e56607 pubmed publisher
Jessen B, Bode S, Ammann S, Chakravorty S, Davies G, Diestelhorst J, et al. The risk of hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type 2. Blood. 2013;121:2943-51 pubmed publisher
Chopra M, Riedel S, Biehl M, Krieger S, von Krosigk V, Bäuerlein C, et al. Tumor necrosis factor receptor 2-dependent homeostasis of regulatory T cells as a player in TNF-induced experimental metastasis. Carcinogenesis. 2013;34:1296-303 pubmed publisher
Ioannou M, Alissafi T, Boon L, Boumpas D, Verginis P. In vivo ablation of plasmacytoid dendritic cells inhibits autoimmunity through expansion of myeloid-derived suppressor cells. J Immunol. 2013;190:2631-40 pubmed publisher
Chamoto K, Gibney B, Lee G, Ackermann M, Konerding M, Tsuda A, et al. Migration of CD11b+ accessory cells during murine lung regeneration. Stem Cell Res. 2013;10:267-77 pubmed publisher
Sun B, Mallampati S, Gong Y, Wang D, Lefebvre V, Sun X. Sox4 is required for the survival of pro-B cells. J Immunol. 2013;190:2080-9 pubmed publisher
Yan X, Shichita T, Katsumata Y, Matsuhashi T, Ito H, Ito K, et al. Deleterious effect of the IL-23/IL-17A axis and ??T cells on left ventricular remodeling after myocardial infarction. J Am Heart Assoc. 2012;1:e004408 pubmed publisher
Ma D, Suthar M, Kasahara S, Gale M, Clark E. CD22 is required for protection against West Nile virus Infection. J Virol. 2013;87:3361-75 pubmed publisher
Grothusen C, Schuett H, Hillmer A, Lumpe S, Grote K, Ballmaier M, et al. Role of suppressor of cytokine signaling-1 in murine atherosclerosis. PLoS ONE. 2012;7:e51608 pubmed publisher
Shen F, Tsai C, Wang L, Chang K, Tung Y, Su I, et al. Enterovirus 71 infection increases expression of interferon-gamma-inducible protein 10 which protects mice by reducing viral burden in multiple tissues. J Gen Virol. 2013;94:1019-27 pubmed publisher
Jin J, Yu Q. Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung. J Leukoc Biol. 2013;93:413-25 pubmed publisher
Franke K, Kalucka J, Mamlouk S, Singh R, Muschter A, Weidemann A, et al. HIF-1? is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2?-induced excessive erythropoiesis. Blood. 2013;121:1436-45 pubmed publisher
Schmitt D, O Dee D, Brown M, Horzempa J, Russo B, Morel P, et al. Role of NK cells in host defense against pulmonary type A Francisella tularensis infection. Microbes Infect. 2013;15:201-11 pubmed publisher
Teo T, Lum F, Claser C, Lulla V, Lulla A, Merits A, et al. A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice. J Immunol. 2013;190:259-69 pubmed publisher
McAllister C, Lakhdari O, Pineton de Chambrun G, Gareau M, Broquet A, Lee G, et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol. 2013;190:418-27 pubmed publisher
Gerber S, Sorensen E, Sedlacek A, Lim J, Skrombolas D, Frelinger J, et al. Local expression of interleukin-2 by B16 melanoma cells results in decreased tumour growth and long-term tumour dormancy. Immunology. 2013;138:280-92 pubmed publisher
Deguine J, Breart B, Lemaitre F, Bousso P. Cutting edge: tumor-targeting antibodies enhance NKG2D-mediated NK cell cytotoxicity by stabilizing NK cell-tumor cell interactions. J Immunol. 2012;189:5493-7 pubmed publisher
Zhang W, Tsuda M, Yang G, Tsuneyama K, He X, Ansari A, et al. Lymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGF? receptor II. PLoS ONE. 2012;7:e49413 pubmed publisher
Navarathna D, Lionakis M, Lizak M, Munasinghe J, Nickerson K, Roberts D. Urea amidolyase (DUR1,2) contributes to virulence and kidney pathogenesis of Candida albicans. PLoS ONE. 2012;7:e48475 pubmed publisher
Sag D, Wingender G, Nowyhed H, Wu R, Gebre A, Parks J, et al. ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development. J Immunol. 2012;189:5129-38 pubmed publisher
Merino E, Abeyweera T, Firth M, Zawislak C, Basu R, Liu X, et al. Protein kinase C-? clustering at immunological synapses amplifies effector responses in NK cells. J Immunol. 2012;189:4859-69 pubmed publisher
Tosello Trampont A, Landes S, Nguyen V, Novobrantseva T, Hahn Y. Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-? production. J Biol Chem. 2012;287:40161-72 pubmed publisher
Kaji T, Ishige A, Hikida M, Taka J, Hijikata A, Kubo M, et al. Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory. J Exp Med. 2012;209:2079-97 pubmed publisher
Rogers E, Wang B, Cui Z, Rowley D, Ressler S, Vyakarnam A, et al. WFDC1/ps20: a host factor that influences the neutrophil response to murine hepatitis virus (MHV) 1 infection. Antiviral Res. 2012;96:158-68 pubmed publisher
de Andrade Pereira B, Fraefel C, Hilbe M, Ackermann M, Dresch C. Transcriptional targeting of DCs with lentiviral vectors induces antigen-specific tolerance in a mouse model of multiple sclerosis. Gene Ther. 2013;20:556-66 pubmed publisher
Dickgreber N, Farrand K, van Panhuys N, Knight D, McKee S, Chong M, et al. Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion. J Leukoc Biol. 2012;92:999-1009 pubmed publisher
Sonn C, Choi J, Kim T, Yu Y, Kim K, Shin S, et al. Augmentation of natural cytotoxicity by chronic low-dose ionizing radiation in murine natural killer cells primed by IL-2. J Radiat Res. 2012;53:823-9 pubmed publisher
Goulding J, Bogue R, Tahiliani V, Croft M, Salek Ardakani S. CD8 T cells are essential for recovery from a respiratory vaccinia virus infection. J Immunol. 2012;189:2432-40 pubmed publisher
Wang X, Sun R, Wei H, Tian Z. High-mobility group box 1 (HMGB1)-Toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of ?? T cells with macrophages. Hepatology. 2013;57:373-84 pubmed publisher
Do J, Valujskikh A, Vignali D, Fairchild R, Min B. Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A. 2012;109:12698-703 pubmed publisher
Shah H, Devera T, Rampuria P, Lang G, Lang M. Type II NKT cells facilitate Alum-sensing and humoral immunity. J Leukoc Biol. 2012;92:883-93 pubmed publisher
Martins V, Ruggiero E, Schlenner S, Madan V, Schmidt M, Fink P, et al. Thymus-autonomous T cell development in the absence of progenitor import. J Exp Med. 2012;209:1409-17 pubmed publisher
Barra N, Chew M, Reid S, Ashkar A. Interleukin-15 treatment induces weight loss independent of lymphocytes. PLoS ONE. 2012;7:e39553 pubmed publisher
Coquery C, Loo W, Buszko M, Lannigan J, Erickson L. Optimized protocol for the isolation of spleen-resident murine neutrophils. Cytometry A. 2012;81:806-14 pubmed publisher
Fiole D, Touvrey C, Quesnel Hellmann A, Douady J, Tournier J. Shape-based tracking allows functional discrimination of two immune cell subsets expressing the same fluorescent tag in mouse lung explant. PLoS ONE. 2012;7:e39831 pubmed publisher
Liu Q, Smith C, Zhang W, Burns A, Li Z. NK cells modulate the inflammatory response to corneal epithelial abrasion and thereby support wound healing. Am J Pathol. 2012;181:452-62 pubmed publisher
Belyaev N, Biro J, Athanasakis D, Fernandez Reyes D, Potocnik A. Global transcriptional analysis of primitive thymocytes reveals accelerated dynamics of T cell specification in fetal stages. Immunogenetics. 2012;64:591-604 pubmed publisher
Notake T, Horisawa S, Sanjo H, Miyagawa S, Hida S, Taki S. Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors. J Immunol. 2012;188:4838-45 pubmed publisher
Wortham B, Eppert B, Motz G, Flury J, Orozco Levi M, Hoebe K, et al. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol. 2012;188:4468-75 pubmed publisher
DRUTMAN S, Kendall J, Trombetta E. Inflammatory spleen monocytes can upregulate CD11c expression without converting into dendritic cells. J Immunol. 2012;188:3603-10 pubmed publisher
Cherrier M, Sawa S, Eberl G. Notch, Id2, and ROR?t sequentially orchestrate the fetal development of lymphoid tissue inducer cells. J Exp Med. 2012;209:729-40 pubmed publisher
Staehli F, Ludigs K, Heinz L, Seguín Estévez Q, Ferrero I, Braun M, et al. NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells. J Immunol. 2012;188:3820-8 pubmed publisher
Zhao Y, French A. Two-compartment model of NK cell proliferation: insights from population response to IL-15 stimulation. J Immunol. 2012;188:2981-90 pubmed publisher
Rode I, Boehm T. Regenerative capacity of adult cortical thymic epithelial cells. Proc Natl Acad Sci U S A. 2012;109:3463-8 pubmed publisher
Gil Bernabé A, Ferjancic S, Tlalka M, Zhao L, Allen P, Im J, et al. Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice. Blood. 2012;119:3164-75 pubmed publisher
Fotin Mleczek M, Zanzinger K, Heidenreich R, Lorenz C, Thess A, Duchardt K, et al. Highly potent mRNA based cancer vaccines represent an attractive platform for combination therapies supporting an improved therapeutic effect. J Gene Med. 2012;14:428-39 pubmed publisher
Doloff J, Waxman D. VEGF receptor inhibitors block the ability of metronomically dosed cyclophosphamide to activate innate immunity-induced tumor regression. Cancer Res. 2012;72:1103-15 pubmed publisher
Tian L, De Hertogh G, Fedeli M, Staats K, Schonefeldt S, Humblet Baron S, et al. Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice. J Autoimmun. 2012;38:39-48 pubmed publisher
Rose S, Misharin A, Perlman H. A novel Ly6C/Ly6G-based strategy to analyze the mouse splenic myeloid compartment. Cytometry A. 2012;81:343-50 pubmed publisher
Freitas do Rosário A, Lamb T, Spence P, Stephens R, Lang A, Roers A, et al. IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol. 2012;188:1178-90 pubmed publisher
Siggs O, Li X, Xia Y, Beutler B. ZBTB1 is a determinant of lymphoid development. J Exp Med. 2012;209:19-27 pubmed publisher
Kadowaki T, Arikawa T, Shinonaga R, Oomizu S, Inagawa H, Soma G, et al. Galectin-9 signaling prolongs survival in murine lung-cancer by inducing macrophages to differentiate into plasmacytoid dendritic cell-like macrophages. Clin Immunol. 2012;142:296-307 pubmed publisher
Mitrovic M, Arapovic J, Jordan S, Fodil Cornu N, Ebert S, Vidal S, et al. The NK cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8(+) T-cell response. J Virol. 2012;86:2165-75 pubmed publisher
Tang X, Tian L, Esteso G, Choi S, Barrow A, Colonna M, et al. Leukocyte-associated Ig-like receptor-1-deficient mice have an altered immune cell phenotype. J Immunol. 2012;188:548-58 pubmed publisher
Rossi L, Avila D, Spallanzani R, Ziblat A, Fuertes M, Lapyckyj L, et al. Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression. J Leukoc Biol. 2012;91:321-31 pubmed publisher
Chamoto K, Gibney B, Ackermann M, Lee G, Lin M, Konerding M, et al. Alveolar macrophage dynamics in murine lung regeneration. J Cell Physiol. 2012;227:3208-15 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
NK1.1 Monoclonal Antibody (PK136), Biotin, eBioscience™
Catalog # :
13-5941-85
Quantity :
500 µg
Price :
US 309.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test
Species :
Mouse
Clone :
PK136
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
NK1.1 (Killer cell lectin-like receptor subfamily B, member 1, KLRB1, NKR-P1A, CD161, cluster of differentiation 161), refers to Natural Killer (NK) cells, lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus. NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test
Aliases :
AI462337; CD161; CD161 antigen-like family member B; CD161 antigen-like family member C; CD161b; CD161c; EMBL:AAQ11375.1}; Inhibitory receptor NKR-P1B; killer cell lectin-like receptor subfamily A member 1C; killer cell lectin-like receptor subfamily B member 1B; killer cell lectin-like receptor subfamily B member 1B allele A; Killer cell lectin-like receptor subfamily B member 1B allele B; killer cell lectin-like receptor subfamily B member 1B allele C; killer cell lectin-like receptor subfamily B member 1C; killer cell lectin-like receptor subfamily B member 1D; killer cell lectin-like receptor subfamily B member 1F; KLRB1; Klrb1b; klrb1b {ECO:0000312; Klrb1c; Klrb1d; Klrb1f; klrb1f {ECO:0000250; Ly55; Ly-55; Ly55b; ly-55b; Ly55c; ly-55c; Ly55d; Ly-55d; Ly59; Ly-59; lymphocyte antigen 55 complex, locus B; lymphocyte antigen 55 complex, locus C; lymphocyte antigen 55 complex, locus D; lymphocyte antigen 55b; lymphocyte antigen 55c; Lymphocyte antigen 55d; lymphocyte antigen 59; MGC163757; MGC163759; natural killer cell receptor protein NKR-P1B; natural killer cell receptor protein NKR-P1C; natural killer cell receptor-P1; natural killer cell surface protein NKR-P1B allele B6; Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344; natural killer cell surface protein NKR-P1B allele SJL/BALB; natural killer cell surface protein NKR-P1B allele TO; natural killer cell surface protein NKR-P1F; Natural killer cell surface protein P1-40; natural killer cell-associated antigen 1; natural killer cells; nk cells; Nk1; Nk-1; NK1.1; Nk1.2; Nk-1.2; NKRP1; NK-RP1; NKR-P1 34; NKR-P1 40; NKR-P1.9; NKRP140; Nkrp1b; NKR-P1B; Nkrp1-b; NKR-P1B protein; Nkrp1c; NKR-P1C; Nkrp1d; NKR-P1D; Nkrp1f; NKR-P1F; RGD:2975}; UniProtKB:Q8VD98}
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA