This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IgM Monoclonal Antibody (II/41), Biotin, eBioscience
catalog :
13-5790-82
quantity :
100 ug
price :
US 159.00
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
II/41
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 47
Reference
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Xu Y, Zhou H, Post G, Zan H, Casali P. Rad52 mediates class-switch DNA recombination to IgD. Nat Commun. 2022;13:980 pubmed publisher
Agarwal P, Li H, Choi K, Hueneman K, He J, Welner R, et al. TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling. Cell Rep. 2021;36:109386 pubmed publisher
Xu J, Xu K, Jung S, Conte A, Lieberman J, Muecksch F, et al. Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants. Nature. 2021;595:278-282 pubmed publisher
Zhang R, Prabakaran P, Yu X, Mackness B, Boudanova E, Hopke J, et al. A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies. MAbs. 2021;13:1904546 pubmed publisher
Cohen A, Yang Z, Gnanapragasam P, Ou S, Dam K, Wang H, et al. Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers. PLoS ONE. 2021;16:e0247963 pubmed publisher
Rivas M, Meydan C, Chin C, Challman M, Kim D, Bhinder B, et al. Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation. Nat Immunol. 2021;22:240-253 pubmed publisher
Zhou X, Zhu X, Li C, Li Y, Ye Z, Shapiro V, et al. Stearoyl-CoA Desaturase-Mediated Monounsaturated Fatty Acid Availability Supports Humoral Immunity. Cell Rep. 2021;34:108601 pubmed publisher
Montecino Rodriguez E, Dorshkind K. Use of Busulfan to Condition Mice for Bone Marrow Transplantation. STAR Protoc. 2020;1:100159 pubmed publisher
Kamata T, So T, Ahmed Q, Giblett S, Patel B, Luo J, et al. Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development. Cell Rep. 2020;31:107802 pubmed publisher
Soni C, Perez O, Voss W, Pucella J, Serpas L, Mehl J, et al. Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA. Immunity. 2020;52:1022-1038.e7 pubmed publisher
Biram A, Winter E, Denton A, Zaretsky I, Dassa B, Bemark M, et al. B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches. Cell Rep. 2020;30:1910-1922.e5 pubmed publisher
Fallet B, Hao Y, Florova M, Cornille K, de Los Aires A, Girelli Zubani G, et al. Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses. Cell Rep. 2020;30:1013-1026.e7 pubmed publisher
Abraham A, Qiu S, Chacko B, Li H, Paterson A, He J, et al. SIRT1 regulates metabolism and leukemogenic potential in CML stem cells. J Clin Invest. 2019;129:2685-2701 pubmed publisher
Schoeler K, Aufschnaiter A, Messner S, Derudder E, Herzog S, Villunger A, et al. TET enzymes control antibody production and shape the mutational landscape in germinal centre B cells. FEBS J. 2019;286:3566-3581 pubmed publisher
Yen W, Sharma R, Cols M, Lau C, Chaudhry A, Chowdhury P, et al. Distinct Requirements of CHD4 during B Cell Development and Antibody Response. Cell Rep. 2019;27:1472-1486.e5 pubmed publisher
Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, et al. Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice. Cell Rep. 2019;27:561-571.e6 pubmed publisher
Agarwal P, Isringhausen S, Li H, Paterson A, He J, Gomariz Á, et al. Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells. Cell Stem Cell. 2019;24:769-784.e6 pubmed publisher
Weng Q, Hu F, Zhang M, Dong Y, Lv C, Wang Y, et al. A protocol for generating induced T cells by reprogramming B cells in vivo. Cell Regen (Lond). 2018;7:7-15 pubmed publisher
Stark A, Chandra A, Chakraborty K, Alam R, Carbonaro V, Clark J, et al. PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner. Nat Commun. 2018;9:3174 pubmed publisher
Yamamoto R, Wilkinson A, Ooehara J, Lan X, Lai C, Nakauchi Y, et al. Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. Cell Stem Cell. 2018;22:600-607.e4 pubmed publisher
Zhang B, Nguyen L, Li L, Zhao D, Kumar B, Wu H, et al. Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia. Nat Med. 2018;24:450-462 pubmed publisher
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, et al. Anti?IL?39 (IL?23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus?like mice. Mol Med Rep. 2017;: pubmed publisher
Suchorska W, Augustyniak E, Richter M, Trzeciak T. Comparison of Four Protocols to Generate Chondrocyte-Like Cells from Human Induced Pluripotent Stem Cells (hiPSCs). Stem Cell Rev. 2017;13:299-308 pubmed publisher
Ikawa T, Masuda K, Endo T, Endo M, Isono K, Koseki Y, et al. Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program. Genes Dev. 2016;30:2475-2485 pubmed
Sakuraba K, Oyamada A, Fujimura K, Spolski R, Iwamoto Y, Leonard W, et al. Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice. Arthritis Res Ther. 2016;18:188 pubmed publisher
Brittain E, Talati M, Fessel J, Zhu H, Penner N, Calcutt M, et al. Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension. Circulation. 2016;133:1936-44 pubmed publisher
Cheong T, Compagno M, Chiarle R. Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system. Nat Commun. 2016;7:10934 pubmed publisher
Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A. 2016;113:1256-60 pubmed publisher
Adachi Y, Onodera T, Yamada Y, Daio R, Tsuiji M, Inoue T, et al. Distinct germinal center selection at local sites shapes memory B cell response to viral escape. J Exp Med. 2015;212:1709-23 pubmed publisher
Hüttl S, Kläsener K, Schweizer M, Schneppenheim J, Oberg H, Kabelitz D, et al. Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells. J Immunol. 2015;195:1548-63 pubmed publisher
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Guo H, Ma O, Friedman A. The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells. J Leukoc Biol. 2014;96:419-26 pubmed publisher
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Lee H, Haque S, Nieto J, Trott J, Inman J, McCormick S, et al. A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion. J Immunol. 2012;188:6093-108 pubmed publisher
Ledesma Soto Y, Blanco Favela F, Fuentes Panana E, Tesoro Cruz E, Hernández González R, Arriaga Pizano L, et al. Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment. BMC Immunol. 2012;13:11 pubmed publisher
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Savitsky D, Calame K. B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion. J Exp Med. 2006;203:2305-14 pubmed
product information
Product Type :
Antibody
Product Name :
IgM Monoclonal Antibody (II/41), Biotin, eBioscience
Catalog # :
13-5790-82
Quantity :
100 ug
Price :
US 159.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
Species :
Mouse
Clone :
II/41
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen. It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum. Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens. It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated. Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test, Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
Aliases :
AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA