MEK1 Monoclonal Antibody (3D9) | Invitrogen 13-3500 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MEK1 Monoclonal Antibody (3D9)

catalog :

13-3500

quantity :

100 µg

price :

425 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3D9

reactivity :

human, mouse, rat, dogs, Xenopus laevis

application :

western blot, immunocytochemistry, immunoprecipitation, proximity ligation assay

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
proximity ligation assay; human; 1:100; fig 8	Brobeil A, KÃ¤mmerer F, Tag C, Steger K, GattenlÃ¶hner S, Wimmer M. PTPIP51â€”A New RelA-tionship with the NFÎºB Signaling Pathway. Biomolecules. 2015;5:485-504 pubmed publisher
	Wang H, Kanungo J, Malbon C. Expression of Galpha 13 (Q226L) induces P19 stem cells to primitive endoderm via MEKK1, 2, or 4. J Biol Chem. 2002;277:3530-6 pubmed
	Greulich H, Erikson R. An analysis of Mek1 signaling in cell proliferation and transformation. J Biol Chem. 1998;273:13280-8 pubmed

product information

Product Type :

Antibody

Product Name :

MEK1 Monoclonal Antibody (3D9)

Catalog # :

13-3500

Quantity :

100 µg

Price :

425 USD

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Canine, Human, Mouse, Non-human primate, Rat, Xenopus laevis

Applications :

Immunocytochemistry: 2-4 µg/mL, Immunofluorescence: 2-4 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1 µg/mL

Species :

Canine, Human, Mouse, Non-human primate, Rat, Xenopus laevis

Clone :

3D9

Isotype :

IgG1

Storage :

-20°C

Description :

MEK1/mitogen activated protein kinase/ERK kinase 1/microtubule-associated protein 2 kinase is a dual specificity kinase and catalyzes both a threonine and a tyrosine residue on MAP kinases ERK1 and ERK2. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in the gene can lead to cardiofaciocutaneous syndrome.

Immunogen :

Purified MEK from human T cells and recombinant MEK1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-4 µg/mL, Immunofluorescence: 2-4 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1 µg/mL

Aliases :

CFC3; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; Map2k1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg

more info or order :

Invitrogen product webpage