CD207 (Langerin) Monoclonal Antibody (eBioL31), Biotin, eBioscience | Invitrogen 13-2075-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD207 (Langerin) Monoclonal Antibody (eBioL31), Biotin, eBioscience

catalog :

13-2075-82

quantity :

100 ug

price :

US 351.00

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

eBioL31

reactivity :

mouse

application :

immunohistochemistry, flow cytometry, immunohistochemistry - frozen section

citations: 20

Reference
Leech J, Dhariwala M, Lowe M, Chu K, Merana G, Cornuot C, et al. Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. Cell Host Microbe. 2019;26:795-809.e5 pubmed publisher
Ng W, Londrigan S, Nasr N, Cunningham A, Turville S, Brooks A, et al. The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus. J Virol. 2016;90:206-21 pubmed publisher
Yoshiki R, Kabashima K, Honda T, Nakamizo S, Sawada Y, Sugita K, et al. IL-23 from Langerhans cells is required for the development of imiquimod-induced psoriasis-like dermatitis by induction of IL-17A-producing ?? T cells. J Invest Dermatol. 2014;134:1912-1921 pubmed publisher
Elnekave M, Furmanov K, Shaul Y, Capucha T, Eli Berchoer L, Zelentsova K, et al. Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming. J Immunol. 2014;192:1395-403 pubmed publisher
Mollah S, Dobrin J, Feder R, Tse S, Matos I, Cheong C, et al. Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. J Invest Dermatol. 2014;134:1265-1275 pubmed publisher
Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, et al. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. J Leukoc Biol. 2013;94:1221-30 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Khandelwal P, Blanco Mezquita T, Emami P, Lee H, Reyes N, Mathew R, et al. Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses. PLoS ONE. 2013;8:e64193 pubmed publisher
Matsuo K, Ishii Y, Kawai Y, Saiba Y, Quan Y, Kamiyama F, et al. Analysis of transcutaneous antigenic protein delivery by a hydrogel patch formulation. J Pharm Sci. 2013;102:1936-1947 pubmed publisher
Dong H, Stanek O, Salvador F, Langer U, Morillon E, Ung C, et al. Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells. Mucosal Immunol. 2013;6:522-34 pubmed publisher
Nakamura T, Nishibu A, Yasoshima M, Tanoue C, Yoshida N, Hatta J, et al. Analysis of Trichophyton antigen-induced contact hypersensitivity in mouse. J Dermatol Sci. 2012;66:144-53 pubmed publisher
Otsuka A, Kubo M, Honda T, Egawa G, Nakajima S, Tanizaki H, et al. Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity. PLoS ONE. 2011;6:e25538 pubmed publisher
Edelson B, Bradstreet T, Hildner K, Carrero J, Frederick K, Kc W, et al. CD8?(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. Immunity. 2011;35:236-48 pubmed publisher
Li H, Kaplan D, Matte Martone C, Tan H, Venkatesan S, Johnson K, et al. Langerhans cells are not required for graft-versus-host disease. Blood. 2011;117:697-707 pubmed publisher
Arthur J, Lich J, Ye Z, Allen I, Gris D, Wilson J, et al. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010;185:4515-9 pubmed publisher
Kratzer R, Mauvais F, Burgevin A, Barilleau E, van Endert P. Fusion proteins for versatile antigen targeting to cell surface receptors reveal differential capacity to prime immune responses. J Immunol. 2010;184:6855-64 pubmed publisher
Loser K, Vogl T, Voskort M, Lueken A, Kupas V, Nacken W, et al. The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells. Nat Med. 2010;16:713-7 pubmed publisher
MANICONE A, Huizar I, McGuire J. Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin). Am J Pathol. 2009;175:2319-31 pubmed publisher
Qiu C, Miyake Y, Kaise H, Kitamura H, Ohara O, Tanaka M. Novel subset of CD8{alpha}+ dendritic cells localized in the marginal zone is responsible for tolerance to cell-associated antigens. J Immunol. 2009;182:4127-36 pubmed publisher
Idoyaga J, Suda N, Suda K, Park C, Steinman R. Antibody to Langerin/CD207 localizes large numbers of CD8alpha+ dendritic cells to the marginal zone of mouse spleen. Proc Natl Acad Sci U S A. 2009;106:1524-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD207 (Langerin) Monoclonal Antibody (eBioL31), Biotin, eBioscience

Catalog # :

13-2075-82

Quantity :

100 ug

Price :

US 351.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.03 ug/test, Immunohistochemistry (Frozen): Assay-Dependent

Species :

Mouse

Clone :

eBioL31

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.03 ug/test, Immunohistochemistry (Frozen): Assay-Dependent

Aliases :

CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913