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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ubiquitin Monoclonal Antibody (Ubi-1)
catalog :
13-1600
quantity :
100 µg
price :
US 375.00
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ubi-1
reactivity :
Saccharomycetales, African green monkey, human, mouse, rat, chicken, bovine, fruit fly , Xenopus laevis, domestic rabbit, rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 83
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:2000; loading ...; fig 6b
Signes A, Cerutti R, Dickson A, Benincá C, Hinchy E, Ghezzi D, et al. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. EMBO Mol Med. 2019;11: pubmed publisher
  • western blot; rat; loading ...; fig 4d
Aukrust I, Rosenberg L, Ankerud M, Bertelsen V, Hollås H, Saraste J, et al. Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes. FEBS Open Bio. 2017;7:160-173 pubmed publisher
  • western blot; human; 1:500; loading ...; fig s7a
Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed publisher
  • western blot; human; loading ...; fig 5
Ding X, Barodia S, Ma L, Goldberg M. Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity. Neurobiol Dis. 2017;98:122-136 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3f
Hu Z, Wang J, Yu D, Soon J, de Kleijn D, Foo R, et al. Aberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy. Sci Rep. 2016;6:35247 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2
Bayram Weston Z, Jones L, Dunnett S, Brooks S. Comparison of mHTT Antibodies in Huntington's Disease Mouse Models Reveal Specific Binding Profiles and Steady-State Ubiquitin Levels with Disease Development. PLoS ONE. 2016;11:e0155834 pubmed publisher
  • immunocytochemistry; fruit fly ; 1:20; fig 2
Bouché V, Espinosa A, Leone L, Sardiello M, Ballabio A, Botas J. Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway. Autophagy. 2016;12:484-98 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig s1
Slowicka K, Vereecke L, Mc Guire C, Sze M, Maelfait J, Kolpe A, et al. Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling. Eur J Immunol. 2016;46:971-80 pubmed publisher
  • western blot; human; fig 5e
Phan L, Chou P, Velazquez Torres G, Samudio I, Parreno K, Huang Y, et al. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nat Commun. 2015;6:7530 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
  • immunocytochemistry; human
Lee S, Lee T, Lee E, Kang S, Park A, Kim S, et al. Identification of a subnuclear body involved in sequence-specific cytokine RNA processing. Nat Commun. 2015;6:5791 pubmed publisher
  • western blot; human
Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed publisher
  • western blot; human; 1:1000; fig 5
Naudin C, Sirvent A, Leroy C, Larive R, Simon V, Pannequin J, et al. SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2. Nat Commun. 2014;5:3159 pubmed publisher
  • western blot; human; fig 5
Brouxhon S, Kyrkanides S, Teng X, Raja V, O Banion M, Clarke R, et al. Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clin Cancer Res. 2013;19:3234-46 pubmed publisher
  • western blot; human; fig 1
Choudhury S, Kolukula V, Preet A, Albanese C, Avantaggiati M. Dissecting the pathways that destabilize mutant p53: the proteasome or autophagy?. Cell Cycle. 2013;12:1022-9 pubmed publisher
  • immunocytochemistry; human
  • immunohistochemistry; human
  • western blot; human
  • immunocytochemistry; African green monkey
  • western blot; African green monkey
Kirilyuk A, Shimoji M, Catania J, Sahu G, Pattabiraman N, Giordano A, et al. An intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregation. PLoS ONE. 2012;7:e48243 pubmed publisher
  • western blot; human; fig 3
Kensche T, Tokunaga F, Ikeda F, Goto E, Iwai K, Dikic I. Analysis of nuclear factor-?B (NF-?B) essential modulator (NEMO) binding to linear and lysine-linked ubiquitin chains and its role in the activation of NF-?B. J Biol Chem. 2012;287:23626-34 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 1
Schwab C, Yu S, McGeer P. Optineurin is colocalized with ubiquitin in Marinesco bodies. Acta Neuropathol. 2012;123:289-92 pubmed publisher
  • immunohistochemistry; human; fig 1
Ginsberg S, Alldred M, Che S. Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease. Neurobiol Dis. 2012;45:99-107 pubmed publisher
  • western blot; human; 1:2000; fig 5g
Rico Bautista E, Yang C, Lu L, Roth G, Wolf D. Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells. BMC Biol. 2010;8:153 pubmed publisher
  • immunohistochemistry; mouse; 1:250; fig 4
Duvick L, Barnes J, Ebner B, Agrawal S, ANDRESEN M, Lim J, et al. SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776. Neuron. 2010;67:929-35 pubmed publisher
  • immunocytochemistry; human; 1:50; fig 4
  • immunohistochemistry; human; 1:50; fig 4
Takahashi Fujigasaki J, Breidert T, Fujigasaki H, Duyckaerts C, Camonis J, Brice A, et al. Amyloid precursor-like protein 2 cleavage contributes to neuronal intranuclear inclusions and cytotoxicity in spinocerebellar ataxia-7 (SCA7). Neurobiol Dis. 2011;41:33-42 pubmed publisher
  • immunohistochemistry; fruit fly ; 1:200; fig 6
Nisoli I, Chauvin J, Napoletano F, Calamita P, Zanin V, Fanto M, et al. Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy. Cell Death Differ. 2010;17:1577-87 pubmed publisher
  • western blot; rat; fig 6
Guttman M, Betts G, Barnes H, Ghassemian M, van der Geer P, Komives E. Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1. Proteomics. 2009;9:5016-28 pubmed publisher
  • western blot; mouse; fig 6
Wiseman R, Chin K, Haynes C, Stanhill A, Xu C, Roguev A, et al. Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle. J Biol Chem. 2009;284:15233-45 pubmed publisher
  • immunohistochemistry; mouse; 1:500
Zhu H, Rothermel B, Hill J. Autophagy in load-induced heart disease. Methods Enzymol. 2009;453:343-63 pubmed publisher
  • western blot; Saccharomycetales
den Dulk B, van Eijk P, de Ruijter M, Brandsma J, Brouwer J. The NER protein Rad33 shows functional homology to human Centrin2 and is involved in modification of Rad4. DNA Repair (Amst). 2008;7:858-68 pubmed publisher
  • immunocytochemistry; human; 4 mg/ml
Marvin Guy L, Duncan P, Wagnière S, Antille N, Porta N, Affolter M, et al. Rapid identification of differentiation markers from whole epithelial cells by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry and statistical analysis. Rapid Commun Mass Spectrom. 2008;22:1099-108 pubmed publisher
  • western blot; human
Nakamura N, Hirose S. Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane. Mol Biol Cell. 2008;19:1903-11 pubmed publisher
  • western blot; mouse; fig 1
Tanaka T, Grusby M, Kaisho T. PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. Nat Immunol. 2007;8:584-91 pubmed
  • western blot; human; 1:1000; fig 7
Nomura N, Nomura M, Newcomb E, Zagzag D. Geldanamycin induces G2 arrest in U87MG glioblastoma cells through downregulation of Cdc2 and cyclin B1. Biochem Pharmacol. 2007;73:1528-36 pubmed
  • western blot; mouse; fig 4d
Gallagher E, Enzler T, Matsuzawa A, Anzelon Mills A, Otero D, Holzer R, et al. Kinase MEKK1 is required for CD40-dependent activation of the kinases Jnk and p38, germinal center formation, B cell proliferation and antibody production. Nat Immunol. 2007;8:57-63 pubmed
  • western blot; human
Bloom J, Pagano M. Experimental tests to definitively determine ubiquitylation of a substrate. Methods Enzymol. 2005;399:249-66 pubmed
  • western blot; human; 1:1000; fig 5
Nomura M, Nomura N, Yamashita J. Geldanamycin-induced degradation of Chk1 is mediated by proteasome. Biochem Biophys Res Commun. 2005;335:900-5 pubmed
  • immunoprecipitation; human
Lensch M, Tischkowitz M, Christianson T, Reifsteck C, Speckhart S, Jakobs P, et al. Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia. Blood. 2003;102:7-16 pubmed
  • immunoprecipitation; human; fig 2
Alberti S, Demand J, Esser C, Emmerich N, Schild H, Hohfeld J. Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome. J Biol Chem. 2002;277:45920-7 pubmed
  • western blot; human; fig 8
Kassenbrock C, Hunter S, Garl P, Johnson G, Anderson S. Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor. J Biol Chem. 2002;277:24967-75 pubmed
  • immunohistochemistry; rat; 1:200; tbl 1
Tan Z, Sankar R, Tu W, Shin D, Liu H, Wasterlain C, et al. Immunohistochemical study of p53-associated proteins in rat brain following lithium-pilocarpine status epilepticus. Brain Res. 2002;929:129-38 pubmed
  • western blot; mouse; fig 2
Floyd Z, Stephens J. Interferon-gamma-mediated activation and ubiquitin-proteasome-dependent degradation of PPARgamma in adipocytes. J Biol Chem. 2002;277:4062-8 pubmed
  • western blot; human; fig 2
Ruffner H, Joazeiro C, Hemmati D, Hunter T, Verma I. Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci U S A. 2001;98:5134-9 pubmed
  • western blot; rhesus macaque; fig 5
Verdier F, Chretien S, Muller O, Varlet P, Yoshimura A, Gisselbrecht S, et al. Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein. J Biol Chem. 1998;273:28185-90 pubmed
  • immunoprecipitation; domestic rabbit; fig 5d
Nielsen K, Papageorge A, Vass W, Willumsen B, Lowy D. The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1. Mol Cell Biol. 1997;17:7132-8 pubmed
Wu H, Ng D, Cheong I, Matsudaira P. The degradation-promoting roles of deubiquitinases Ubp6 and Ubp3 in cytosolic and ER protein quality control. PLoS ONE. 2020;15:e0232755 pubmed publisher
Chan S, Prasad R, Matsudaira P. Genetic Selection Based on a Ste6*C-HA-Ura3 Substrate Identifies New Cytosolic Quality Control Alleles in Saccharomyces cerevisiae. G3 (Bethesda). 2020;10:1879-1891 pubmed publisher
Jia R, Bonifacino J. Negative regulation of autophagy by UBA6-BIRC6-mediated ubiquitination of LC3. elife. 2019;8: pubmed publisher
Chai Q, Wang X, Qiang L, Zhang Y, Ge P, Lu Z, et al. A Mycobacterium tuberculosis surface protein recruits ubiquitin to trigger host xenophagy. Nat Commun. 2019;10:1973 pubmed publisher
Kim J, Alavi Naini F, Sun Y, Ma L. Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin. Am J Cancer Res. 2018;8:1823-1836 pubmed
Lei Y, Liu K, Hou L, Ding L, Li Y, Liu L. Small chaperons and autophagy protected neurons from necrotic cell death. Sci Rep. 2017;7:5650 pubmed publisher
Wei J, Dong S, Bowser R, Khoo A, Zhang L, Jacko A, et al. Regulation of the ubiquitylation and deubiquitylation of CREB-binding protein modulates histone acetylation and lung inflammation. Sci Signal. 2017;10: pubmed publisher
Wang L, Gundelach J, Bram R. Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme. Cell Death Dis. 2017;8:e2807 pubmed publisher
Dadson K, Hauck L, Hao Z, Grothe D, Rao V, Mak T, et al. The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1. Sci Rep. 2017;7:41490 pubmed publisher
Fu J, Li S, Feng R, Ma H, Sabeh F, Roodman G, et al. Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease. J Clin Invest. 2016;126:1759-72 pubmed publisher
Richter B, Sliter D, Herhaus L, Stolz A, Wang C, Beli P, et al. Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria. Proc Natl Acad Sci U S A. 2016;113:4039-44 pubmed publisher
Grindheim A, Hollås H, Raddum A, Saraste J, Vedeler A. Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2. J Cell Sci. 2016;129:314-28 pubmed publisher
Chang J, Zhang W, Yeh H, de Jong E, Jun S, Kim K, et al. mRNA 3'-UTR shortening is a molecular signature of mTORC1 activation. Nat Commun. 2015;6:7218 pubmed publisher
Christensen H, Trotter C, Hickman M, Edmunds W. Re-evaluating cost effectiveness of universal meningitis vaccination (Bexsero) in England: modelling study. BMJ. 2014;349:g5725 pubmed publisher
Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed publisher
Kim M, Park H, Park H, Ro S, Nam S, Reed J, et al. Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging. Autophagy. 2013;9:1201-13 pubmed publisher
Rodriguez O, Choudhury S, Kolukula V, Vietsch E, Catania J, Preet A, et al. Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy. Cell Cycle. 2012;11:4436-46 pubmed publisher
Kageyama Y, Zhang Z, Roda R, Fukaya M, Wakabayashi J, Wakabayashi N, et al. Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage. J Cell Biol. 2012;197:535-51 pubmed publisher
Koga H, Martinez Vicente M, Macian F, Verkhusha V, Cuervo A. A photoconvertible fluorescent reporter to track chaperone-mediated autophagy. Nat Commun. 2011;2:386 pubmed publisher
Mulvihill M, Guttman M, Komives E. Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein. Biochemistry. 2011;50:6208-16 pubmed publisher
Talbot K, Louneva N, Cohen J, Kazi H, Blake D, Arnold S. Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location. PLoS ONE. 2011;6:e16886 pubmed publisher
Zhao R, Yeung S, Chen J, Iwakuma T, Su C, Chen B, et al. Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J Clin Invest. 2011;121:851-65 pubmed publisher
Hewawasam G, Shivaraju M, Mattingly M, Venkatesh S, Martin Brown S, Florens L, et al. Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4. Mol Cell. 2010;40:444-54 pubmed publisher
Thompson L, Aiken C, Kaltenbach L, Agrawal N, Illes K, Khoshnan A, et al. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol. 2009;187:1083-99 pubmed publisher
Willuweit A, Velden J, Godemann R, Manook A, Jetzek F, Tintrup H, et al. Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's disease. PLoS ONE. 2009;4:e7931 pubmed publisher
Tseng P, Matsuzawa A, Zhang W, Mino T, Vignali D, Karin M. Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol. 2010;11:70-5 pubmed publisher
Bjørkhaug L, Molnes J, Søvik O, Njølstad P, Flatmark T. Allosteric activation of human glucokinase by free polyubiquitin chains and its ubiquitin-dependent cotranslational proteasomal degradation. J Biol Chem. 2007;282:22757-64 pubmed
Gallagher E, Gao M, Liu Y, Karin M. Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change. Proc Natl Acad Sci U S A. 2006;103:1717-22 pubmed
Huang M, Kamasani U, Prendergast G. RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3. Oncogene. 2006;25:1281-9 pubmed
Ved R, Saha S, Westlund B, Perier C, Burnam L, Sluder A, et al. Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. J Biol Chem. 2005;280:42655-42668 pubmed publisher
Alzayady K, Panning M, Kelley G, Wojcikiewicz R. Involvement of the p97-Ufd1-Npl4 complex in the regulated endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors. J Biol Chem. 2005;280:34530-7 pubmed
Berke S, Chai Y, Marrs G, Wen H, Paulson H. Defining the role of ubiquitin-interacting motifs in the polyglutamine disease protein, ataxin-3. J Biol Chem. 2005;280:32026-34 pubmed
Niwa Y, Kanda H, Shikauchi Y, Saiura A, Matsubara K, Kitagawa T, et al. Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene. 2005;24:6406-17 pubmed
Kothe M, Ye Y, Wagner J, De Luca H, Kern E, Rapoport T, et al. Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate. J Biol Chem. 2005;280:28127-32 pubmed
Gannot G, Gillespie J, Chuaqui R, Tangrea M, Linehan W, Emmert Buck M. Histomathematical analysis of clinical specimens: challenges and progress. J Histochem Cytochem. 2005;53:177-85 pubmed
Yeh E, Cunningham M, Arnold H, Chasse D, Monteith T, Ivaldi G, et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat Cell Biol. 2004;6:308-18 pubmed
Sawada H, Kohno R, Kihara T, Izumi Y, Sakka N, Ibi M, et al. Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions. J Biol Chem. 2004;279:10710-9 pubmed
Elkabetz Y, Shapira I, Rabinovich E, Bar Nun S. Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates: roles of endoplamic reticulum-bound p97/Cdc48p and proteasome. J Biol Chem. 2004;279:3980-9 pubmed
Dewson G, Snowden R, Almond J, Dyer M, Cohen G. Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells. Oncogene. 2003;22:2643-54 pubmed
Finley K, Edeen P, Cumming R, Mardahl Dumesnil M, Taylor B, Rodriguez M, et al. blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration. J Neurosci. 2003;23:1254-64 pubmed
Sarcevic B, Mawson A, Baker R, Sutherland R. Regulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylation. EMBO J. 2002;21:2009-18 pubmed
Hirano S, Kimoto N, Shimoyama Y, Hirohashi S, Takeichi M. Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell. 1992;70:293-301 pubmed
product information
Product Type :
Antibody
Product Name :
Ubiquitin Monoclonal Antibody (Ubi-1)
Catalog # :
13-1600
Quantity :
100 µg
Price :
US 375.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Bovine, Chicken, Human, Mouse, Xenopus laevis
Applications :
ELISA: 0.1-1 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
Species :
Bovine, Chicken, Human, Mouse, Xenopus laevis
Clone :
Ubi-1
Isotype :
IgG1, kappa
Storage :
-20°C
Description :
Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified.
Immunogen :
Purified bovine ubiquitin conjugated to carrier protein
Format :
Liquid
Applications w/Dilutions :
ELISA: 0.1-1 µg/mL, Immunohistochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-3 µg/mL
Aliases :
0610006J14Rik; 1810034D23Rik; 2700054O04Rik; 40S ribosomal protein S27a; 40S ribosomal protein S27-like; 40S ribosomal protein S27-like protein; AI194771; AL033289; CEP80; CG5271; CG5271-PA; Chap1; Dmel CG5271; Dmel_CG5271; Dub80; epididymis luminal protein 112; epididymis secretory protein Li 50; HEL112; HEL-S-50; hm:zeh0386; HMG20; hPLIC-2; HRIHFB2157; HUBCEP52; ik:tdsubc_1f2; l(2)04820; l(2)31Ei; LOC100912032; LOC101747587; male female sterile 31; mfs(2)31; mfs(2)48; mfs48; OTTHUMP00000200786; OTTHUMP00000201692; PLIC-2; polyubiquitin; polyubiquitin B; polyubiquitin C; poly-ubiquitin precursor; polyubiquitin-B; Polyubiquitin-C; polyubiquitin-C-like; RE44350p; ribosomal protein S27; ribosomal protein S27 like; ribosomal protein S27A; ribosomal protein S27a L homeolog; ribosomal protein S27a S homeolog; ribosomal protein S27-like; ribosomal protein S27-like protein; RPL40; RpS27; Rps27a; rps27a.L; rps27a.S; RpS27A-PA; RPS27L; S27A; similar to polyubiquitin; similar to ubiquitin-S27a fusion protein; Small ribosomal subunit protein eS27-like; Small ribosomal subunit protein eS31; tdsubc_1f2; TI-225; UB3-D; Uba52; UBA80; UBB; Ubb2; UBC; UBCEP1; UBCEP80; Ubi-f80; Ubi-m; Ubiq; Ubiquilin 2; ubiquitin; ubiquitin (34 AA) (1 is 2nd base in codon); ubiquitin and ribosomal protein S27a; ubiquitin B; ubiquitin C; ubiquitin carboxyl extension protein 80; ubiquitin copy 4; ubiquitin fusion 80; ubiquitin polyprotein (heat shock related); ubiquitin/ribosomal protein; ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like; ubiquitin-CEP80; ubiquitin-hybrid protein precursor; Ubiquitin-monomeric; Ubiquitin-related; Ubiquitin-related 1; Ubiquitin-related 2; ubiquitin-S27a fusion protein; Unknown (protein for MGC:127652); unnamed protein product; XELAEV_18028796mg; xx:tdsubc_1f2; zgc:66168; zgc:66168 protein
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA