MAP2 Monoclonal Antibody (M13) | Invitrogen 13-1500 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MAP2 Monoclonal Antibody (M13)

catalog :

13-1500

quantity :

100 µg

price :

US 428

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M13

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 39

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; loading ...; fig 1b	Zhu L, Tan B, Dwight S, Beahm B, Wilsey M, Crawford B, et al. AAV9-NGLY1 gene replacement therapy improves phenotypic and biomarker endpoints in a rat model of NGLY1 Deficiency. Mol Ther Methods Clin Dev. 2022;27:259-271 pubmed publisher
immunocytochemistry; human	Taylor A, Vagaska B, Edgington R, HÃ©bert C, Ferretti P, Bergonzo P, et al. Biocompatibility of nanostructured boron doped diamond for the attachment and proliferation of human neural stem cells. J Neural Eng. 2015;12:066016 pubmed publisher
immunocytochemistry; human; 1:200	Cerbini T, Funahashi R, Luo Y, Liu C, Park K, Rao M, et al. Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines. PLoS ONE. 2015;10:e0116032 pubmed publisher
immunohistochemistry; mouse; 1:1000; fig 4	Lee D, CHUNG J, Chung K, Kang M. Reactive oxygen species (ROS) modulate AMPA receptor phosphorylation and cell-surface localization in concert with pain-related behavior. Pain. 2012;153:1905-15 pubmed publisher
immunocytochemistry; human; fig 1	Coyle D, Li J, Baccei M. Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons. PLoS ONE. 2011;6:e16174 pubmed publisher
immunohistochemistry - paraffin section; human; 1:400; tbl 3	Han C, Min B, Kim Y, Jeong E, Park C, Woo Y, et al. Immunohistochemical analysis of developmental neural antigen expression in the balloon cells of focal cortical dysplasia. J Clin Neurosci. 2011;18:114-8 pubmed publisher
immunohistochemistry - frozen section; human; fig 2	Fevre Montange M, Grand S, Champier J, Hoffmann D, Pasquier B, Jouvet A. Bcl-2 expression in a papillary tumor of the pineal region. Neuropathology. 2008;28:660-3 pubmed publisher
immunocytochemistry; human; 1:500; fig 3	Trimmer P, Borland M, Keeney P, Bennett J, Parker W. Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies. J Neurochem. 2004;88:800-12 pubmed
immunoprecipitation; rat western blot; rat	Buddle M, Eberhardt E, Ciminello L, Levin T, Wing R, DiPasquale K, et al. Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation. Brain Res. 2003;978:38-50 pubmed
	Pemberton K, Rosato M, Dedert C, DeLeon C, Arnatt C, Xu F. Differential Effects of the G-Protein-Coupled Estrogen Receptor (GPER) on Rat Embryonic (E18) Hippocampal and Cortical Neurons. Eneuro. 2022;9: pubmed publisher
	Hyun S, Ko M, Jang S, Lee B, Rho J, Kim K, et al. Bisphenol-A impairs synaptic formation and function by RGS4-mediated regulation of BDNF signaling in the cerebral cortex. Dis Model Mech. 2022;15: pubmed publisher
	Hivare P, Gangrade A, Swarup G, Bhavsar K, Singh A, Gupta R, et al. Peptide functionalized DNA hydrogel enhances neuroblastoma cell growth and differentiation. Nanoscale. 2022;14:8611-8620 pubmed publisher
	Que Z, Olivero Acosta M, Zhang J, Eaton M, Tukker A, Chen X, et al. Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant. J Neurosci. 2021;41:10194-10208 pubmed publisher
	Plooster M, Rossi G, Farrell M, McAfee J, Bell J, Ye M, et al. Schizophrenia-Linked Protein tSNARE1 Regulates Endosomal Trafficking in Cortical Neurons. J Neurosci. 2021;41:9466-9481 pubmed publisher
	Chen Q, Yuan C, Jiang S, Heng B, Zou T, Shen Z, et al. Small molecules efficiently reprogram apical papilla stem cells into neuron-like cells. Exp Ther Med. 2021;21:546 pubmed publisher
	Prince L, Neely M, Warren E, Thomas M, Henley M, Smith K, et al. Environmentally relevant developmental methylmercury exposures alter neuronal differentiation in a human-induced pluripotent stem cell model. Food Chem Toxicol. 2021;152:112178 pubmed publisher
	Ortolano N, Romero Morales A, Rasmussen M, Bodnya C, Kline L, Joshi P, et al. A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models. PLoS ONE. 2021;16:e0248000 pubmed publisher
	Fujita Y, Nagakura T, Uchino H, Inazu M, Yamanaka T. Functional Expression of Choline Transporters in Human Neural Stem Cells and Its Link to Cell Proliferation, Cell Viability, and Neurite Outgrowth. Cells. 2021;10: pubmed publisher
	Parekh R, Sriramula S. Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons. Int J Mol Sci. 2020;22: pubmed publisher
	Vijayalingam S, Ezekiel U, Xu F, Subramanian T, Geerling E, Hoelscher B, et al. Human iPSC-Derived Neuronal Cells From CTBP1-Mutated Patients Reveal Altered Expression of Neurodevelopmental Gene Networks. Front Neurosci. 2020;14:562292 pubmed publisher
	Helenes González C, Jayasinghe S, Ferretti P. Bio-electrosprayed human neural stem cells are viable and maintain their differentiation potential. F1000Res. 2020;9:267 pubmed publisher
	Duron D, Lei W, Barker N, Stine C, Mishra S, Blagg B, et al. Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway. Sci Signal. 2020;13: pubmed publisher
	Laudani S, La Cognata V, Iemmolo R, Bonaventura G, Villaggio G, Saccone S, et al. Effect of a Bone Marrow-Derived Extracellular Matrix on Cell Adhesion and Neural Induction of Dental Pulp Stem Cells. Front Cell Dev Biol. 2020;8:100 pubmed publisher
	Dobson Stone C, Hallupp M, Shahheydari H, Ragagnin A, Chatterton Z, Carew Jones F, et al. CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis. Brain. 2020;143:783-799 pubmed publisher
	Parekh R, Robidoux J, Sriramula S. Kinin B1 Receptor Blockade Prevents Angiotensin II-induced Neuroinflammation and Oxidative Stress in Primary Hypothalamic Neurons. Cell Mol Neurobiol. 2020;40:845-857 pubmed publisher
	Taylor A, González C, Ferretti P, Jackman R. Spontaneous Differentiation of Human Neural Stem Cells on Nanodiamonds. Adv Biosyst. 2019;3:e1800299 pubmed publisher
	Inoue F, Kreimer A, Ashuach T, Ahituv N, Yosef N. Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction. Cell Stem Cell. 2019;25:713-727.e10 pubmed publisher
	Gill S, Kumara V. Detecting Neurodevelopmental Toxicity of Domoic Acid and Ochratoxin A Using Rat Fetal Neural Stem Cells. Mar Drugs. 2019;17: pubmed publisher
	Yang Q, Pinto V, Duan W, Paxton E, Dessauer J, Ryan W, et al. In vitro Characteristics of Heterogeneous Equine Hoof Progenitor Cell Isolates. Front Bioeng Biotechnol. 2019;7:155 pubmed publisher
	Yang Q, Lopez M. Ultrastructural morphology is distinct among primary progenitor cell isolates from normal, inflamed, and cryopreserved equine hoof tissue and CD105+K14+ progenitor cells. In Vitro Cell Dev Biol Anim. 2019;55:641-655 pubmed publisher
	Falcucci R, Wertz R, Green J, Meucci O, Salvino J, Fontana A. Novel Positive Allosteric Modulators of Glutamate Transport Have Neuroprotective Properties in an in Vitro Excitotoxic Model. ACS Chem Neurosci. 2019;10:3437-3453 pubmed publisher
	Sharma R, Al Saleem F, Panzer J, Lee J, Puligedda R, Felicori L, et al. Monoclonal antibodies from a patient with anti-NMDA receptor encephalitis. Ann Clin Transl Neurol. 2018;5:935-951 pubmed publisher
	Papa L, Robicsek S, Brophy G, Wang K, Hannay H, Heaton S, et al. Temporal Profile of Microtubule-Associated Protein 2: A Novel Indicator of Diffuse Brain Injury Severity and Early Mortality after Brain Trauma. J Neurotrauma. 2018;35:32-40 pubmed publisher
	Xue L, Li Y, Chen J. Duration of simulated microgravity affects the differentiation of mesenchymal stem cells. Mol Med Rep. 2017;15:3011-3018 pubmed publisher
	Lü L, Mak Y, Fang M, Yew D. The difference in gliosis induced by ?-amyloid and Tau treatments in astrocyte cultures derived from senescence accelerated and normal mouse strains. Biogerontology. 2009;10:695-710 pubmed publisher
	Borland M, Trimmer P, Rubinstein J, Keeney P, Mohanakumar K, Liu L, et al. Chronic, low-dose rotenone reproduces Lewy neurites found in early stages of Parkinson's disease, reduces mitochondrial movement and slowly kills differentiated SH-SY5Y neural cells. Mol Neurodegener. 2008;3:21 pubmed publisher
	Chalmers K, Love S. Neurofibrillary tangles may interfere with Smad 2/3 signaling in neurons. J Neuropathol Exp Neurol. 2007;66:158-67 pubmed
	Mori T, Kiyono T, Imabayashi H, Takeda Y, Tsuchiya K, Miyoshi S, et al. Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential. Mol Cell Biol. 2005;25:5183-95 pubmed
	Arnold S, Lee V, Gur R, Trojanowski J. Abnormal expression of two microtubule-associated proteins (MAP2 and MAP5) in specific subfields of the hippocampal formation in schizophrenia. Proc Natl Acad Sci U S A. 1991;88:10850-4 pubmed

product information

Product Type :

Antibody

Product Name :

MAP2 Monoclonal Antibody (M13)

Catalog # :

13-1500

Quantity :

100 µg

Price :

US 428

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1-0.5 µg/mL, Immunocytochemistry: 1:250-1:400, Immunohistochemistry: 5-10 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1:500

Species :

Human, Mouse, Rat

Clone :

M13

Isotype :

IgG1, kappa

Storage :

-20°C

Description :

MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).

Immunogen :

MAPs

Format :

Liquid

Applications w/Dilutions :

ELISA: 0.1-0.5 µg/mL, Immunocytochemistry: 1:250-1:400, Immunohistochemistry: 5-10 µg/mL, Immunoprecipitation: 2-5 µg, Western Blot: 1:500

Aliases :

a730034c02; AC091465.1; DKFZp686I2148; G1-397-34; MAP 2; Map2; MAP-2; map2.S; map2a; map-2a; map2ab; MAP2B; MAP2C; MAP2R; microtubule associated protein 2; microtubule associated protein 2 S homeolog; microtubule associated protein 2; microtubule-associated protein 2; microtubule associated protein 2C; microtubule-associated protein 2; microtubule-associated protein-2; Mtap2; Mtap-2; OTTHUMP00000163916; OTTHUMP00000208143; repro4; XELAEV_18047318mg; xmap2

more info or order :

Invitrogen product webpage