CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™ | Invitrogen 13-1051-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™

catalog :

13-1051-81

quantity :

50 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

MJ7/18

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 28

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2	Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
flow cytometry; mouse; loading ...; fig 1b	Nasrallah R, Knezevic K, Thai T, Thomas S, GÃ¶ttgens B, Lacaud G, et al. Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis. Biol Open. 2015;4:819-29 pubmed publisher
flow cytometry; mouse; fig 1, 2, 3	Böiers C, Buza Vidas N, Jensen C, Pronk C, Kharazi S, Wittmann L, et al. Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development. Blood. 2010;115:5061-8 pubmed publisher
	Di Genua C, Valletta S, Buono M, Stoilova B, Sweeney C, Rodriguez Meira A, et al. C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor. Cancer Cell. 2020;37:690-704.e8 pubmed publisher
	Huang J, Zhao L, Fan Y, Liao L, Ma P, Xiao G, et al. The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression. Nat Commun. 2019;10:2876 pubmed publisher
	Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao Shen H, et al. Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms. J Clin Invest. 2019;130:1596-1611 pubmed publisher
	Blackshear C, Borrelli M, Shen E, Ransom R, Chung N, Vistnes S, et al. Utilizing Confocal Microscopy to Characterize Human and Mouse Adipose Tissue. Tissue Eng Part C Methods. 2018;: pubmed publisher
	Jin Y, Muhl L, Burmakin M, Wang Y, Duchez A, Betsholtz C, et al. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling. Nat Cell Biol. 2017;19:639-652 pubmed publisher
	Redgrave R, Tual Chalot S, Davison B, Singh E, Hall D, Amirrasouli M, et al. Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis. Stem Cell Reports. 2017;8:1287-1298 pubmed publisher
	Yuan S, Pardue S, Shen X, Alexander J, Orr A, Kevil C. Hydrogen sulfide metabolism regulates endothelial solute barrier function. Redox Biol. 2016;9:157-166 pubmed publisher
	Ojeda Fernandez L, Recio Poveda L, Aristorena M, Lastres P, Blanco F, Sanz Rodriguez F, et al. Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response. PLoS Genet. 2016;12:e1005935 pubmed publisher
	Moen I, Gebre M, Alonso Camino V, Chen D, Epstein D, McDonald D. Anti-metastatic action of FAK inhibitor OXA-11 in combination with VEGFR-2 signaling blockade in pancreatic neuroendocrine tumors. Clin Exp Metastasis. 2015;32:799-817 pubmed publisher
	Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
	Qu X, Zhou B, Scott Baldwin H. Tie1 is required for lymphatic valve and collecting vessel development. Dev Biol. 2015;399:117-128 pubmed publisher
	Cheng C, Lee Y, Lin S, HuangFu W, Liu I. Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells. J Biomed Sci. 2014;21:21 pubmed publisher
	Hartwell K, Miller P, Mukherjee S, Kahn A, Stewart A, Logan D, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013;9:840-848 pubmed publisher
	Cheng C, Lian W, Hsiao F, Liu I, Lin S, Lee Y, et al. Isolation and characterization of novel murine epiphysis derived mesenchymal stem cells. PLoS ONE. 2012;7:e36085 pubmed publisher
	Yan A, Avraham T, Zampell J, Haviv Y, Weitman E, Mehrara B. Adipose-derived stem cells promote lymphangiogenesis in response to VEGF-C stimulation or TGF-?1 inhibition. Future Oncol. 2011;7:1457-73 pubmed publisher
	Grajales L, Garcia J, Banach K, Geenen D. Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development. J Mol Cell Cardiol. 2010;48:735-45 pubmed publisher
	Eliopoulos N, Francois M, Boivin M, Martineau D, Galipeau J. Neo-organoid of marrow mesenchymal stromal cells secreting interleukin-12 for breast cancer therapy. Cancer Res. 2008;68:4810-8 pubmed publisher
	Ross E, Freeman S, Zhao Y, Dhanjal T, Ross E, Lax S, et al. A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow. PLoS ONE. 2008;3:e2338 pubmed publisher
	Wu X, Yu G, Parks H, Hebert T, Goh B, Dietrich M, et al. Circadian mechanisms in murine and human bone marrow mesenchymal stem cells following dexamethasone exposure. Bone. 2008;42:861-70 pubmed publisher
	Mukherjee S, Raje N, Schoonmaker J, Liu J, Hideshima T, Wein M, et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest. 2008;118:491-504 pubmed publisher
	Perez Gomez E, Villa Morales M, Santos J, Fernandez Piqueras J, Gamallo C, Dotor J, et al. A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis. Cancer Res. 2007;67:10268-77 pubmed
	Korpanty G, Carbon J, Grayburn P, Fleming J, Brekken R. Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature. Clin Cancer Res. 2007;13:323-30 pubmed
	Eliopoulos N, Stagg J, Lejeune L, Pommey S, Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice. Blood. 2005;106:4057-65 pubmed
	Onoe T, Ohdan H, Tokita D, Shishida M, Tanaka Y, Hara H, et al. Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. J Immunol. 2005;175:139-46 pubmed
	Quintanilla M, Ramirez J, Perez Gomez E, Romero D, Velasco B, Letarte M, et al. Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis. Oncogene. 2003;22:5976-85 pubmed

product information

Product Type :

Antibody

Product Name :

CD105 (Endoglin) Monoclonal Antibody (MJ7/18), Biotin, eBioscience™

Catalog # :

13-1051-81

Quantity :

50 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

MJ7/18

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); Eng; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein

more info or order :

Invitrogen product webpage