This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD80 (B7-1) Monoclonal Antibody (3H5), Biotin, eBioscience
catalog :
13-0800-82
quantity :
100 ug
price :
US 244.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
3H5

The same clone is also sold as:
reactivity :
rat
application :
flow cytometry
citations: 5
Reference
Du T, Yang C, Ge M, Liu Y, Zhang P, Li H, et al. M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response. Front Immunol. 2020;11:1603 pubmed publisher
Jiang H, Hu H, Zhang Y, Yue P, Ning L, Zhou Y, et al. Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-?B decoy oligodeoxynucleotides. Drug Des Devel Ther. 2017;11:2997-3007 pubmed publisher
Möller K, Pösel C, Kranz A, Schulz I, Scheibe J, Didwischus N, et al. Arterial Hypertension Aggravates Innate Immune Responses after Experimental Stroke. Front Cell Neurosci. 2015;9:461 pubmed publisher
Damoiseaux J, Yagita H, Okumura K, van Breda Vriesman P. Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells. J Leukoc Biol. 1998;64:803-9 pubmed
Maeda K, Sato T, Azuma M, Yagita H, Okumura K. Characterization of rat CD80 and CD86 by molecular cloning and mAb. Int Immunol. 1997;9:993-1000 pubmed
product information
Product Type :
Antibody
Product Name :
CD80 (B7-1) Monoclonal Antibody (3H5), Biotin, eBioscience
Catalog # :
13-0800-82
Quantity :
100 ug
Price :
US 244.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Rat
Applications :
Flow Cytometry: 0.5 ug/test
Species :
Rat
Clone :
3H5
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 ug/test
Aliases :
Activation B7-1 antigen; B7; B7 protein; B7.1; B71; B7-1; B7-1 protein; B7-1 protein precursor; BB1; B-lymphocyte activation antigen B7; Cd28l; CD28LG; CD28LG1; CD80; Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1); CD80 anitgen; CD80 antigen; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); Cd80 molecule; CD80 protein precursor; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; Ly53; Ly-53; MIC17; sCD 80; sCD80; secreted B7-1 protein precursor; soluble CD 80; soluble CD80; T-cell costimulatory molecule; T-cell co-stimulatory protein B7-1; T-lymphocyte activation antigen CD80; TS/A-1; TSA1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA