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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD235a (Glycophorin A) Monoclonal Antibody (HIR2 (GA-R2)), PE, eBioscience™
catalog :
12-9987-82
quantity :
100 µg
price :
US 280
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
HIR2 (GA-R2)
reactivity :
human
application :
flow cytometry
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 5
Kyttälä A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy K, et al. Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential. Stem Cell Reports. 2016;6:200-12 pubmed publisher
  • flow cytometry; human; tbl 2
Liu J, Brzeszczynska J, Samuel K, Black J, Palakkan A, Anderson R, et al. Efficient episomal reprogramming of blood mononuclear cells and differentiation to hepatocytes with functional drug metabolism. Exp Cell Res. 2015;338:203-13 pubmed publisher
  • flow cytometry; human; fig 1
Marino J, Tan C, Taylor A, Bentley C, Van De Wiele C, Ranne R, et al. Differential IL-7 responses in developing human thymocytes. Hum Immunol. 2010;71:329-33 pubmed publisher
Li J, Quan C, He Y, Cao Y, Chen Y, Wang Y, et al. Autophagy regulated by the HIF/REDD1/mTORC1 signaling is progressively increased during erythroid differentiation under hypoxia. Front Cell Dev Biol. 2022;10:896893 pubmed publisher
Kim H, Park J, Kang J, Seo S. Negative Regulation of Erythroid Differentiation via the CBX8-TRIM28 Axis. Mol Cells. 2021;44:444-457 pubmed publisher
Garcia Montolio M, Ballaré C, Blanco E, Gutierrez A, Aranda S, Gomez A, et al. Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells. Front Cell Dev Biol. 2021;9:655201 pubmed publisher
García Alegría E, Potts B, Menegatti S, Kouskoff V. In vitro differentiation of human embryonic stem cells to hemogenic endothelium and blood progenitors via embryoid body formation. STAR Protoc. 2021;2:100367 pubmed publisher
Goldfarb A, Freeman K, Sahu R, Elagib K, Holy M, Arneja A, et al. Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia. Nat Commun. 2021;12:1645 pubmed publisher
Sharma R, Dever D, Lee C, Azizi A, Pan Y, Camarena J, et al. The TRACE-Seq method tracks recombination alleles and identifies clonal reconstitution dynamics of gene targeted human hematopoietic stem cells. Nat Commun. 2021;12:472 pubmed publisher
Dumas A, Pomella N, Rosser G, Guglielmi L, Vinel C, Millner T, et al. Microglia promote glioblastoma via mTOR-mediated immunosuppression of the tumour microenvironment. EMBO J. 2020;39:e103790 pubmed publisher
Xi H, Langerman J, Sabri S, Chien P, Young C, Younesi S, et al. A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. Cell Stem Cell. 2020;27:158-176.e10 pubmed publisher
Zhang J, Liu Y, Han X, Mei Y, Yang J, Zhang Z, et al. Rats provide a superior model of human stress erythropoiesis. Exp Hematol. 2019;78:21-34.e3 pubmed publisher
Wang T, Wen T, Li H, Han B, Hao S, Wang C, et al. Arsenic sulfide nanoformulation induces erythroid differentiation in chronic myeloid leukemia cells through degradation of BCR-ABL. Int J Nanomedicine. 2019;14:5581-5594 pubmed publisher
Ludwig L, Lareau C, Bao E, Nandakumar S, Muus C, Ulirsch J, et al. Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis. Cell Rep. 2019;27:3228-3240.e7 pubmed publisher
Nandakumar S, McFarland S, Mateyka L, Lareau C, Ulirsch J, Ludwig L, et al. Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis. elife. 2019;8: pubmed publisher
Lopez Yrigoyen M, Yang C, Fidanza A, Cassetta L, Taylor A, McCahill A, et al. Genetic programming of macrophages generates an in vitro model for the human erythroid island niche. Nat Commun. 2019;10:881 pubmed publisher
Hu P, Nebreda A, Hanenberg H, Kinnebrew G, Ivan M, Yoder M, et al. P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim. Nat Commun. 2018;9:3518 pubmed publisher
Tanimura N, Liao R, Wilson G, Dent M, Cao M, Burstyn J, et al. GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism. Dev Cell. 2018;46:581-594.e4 pubmed publisher
Krishnamoorthy S, Pace B, Gupta D, Sturtevant S, Li B, Makala L, et al. Dimethyl fumarate increases fetal hemoglobin, provides heme detoxification, and corrects anemia in sickle cell disease. JCI Insight. 2017;2: pubmed publisher
Canver M, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern E, et al. Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. Nat Genet. 2017;49:625-634 pubmed publisher
Liu T, Krysiak K, Shirai C, Kim S, Shao J, Ndonwi M, et al. Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells. PLoS ONE. 2017;12:e0170470 pubmed publisher
Yang C, Ma R, Axton R, Jackson M, Taylor A, Fidanza A, et al. Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells. Stem Cells. 2017;35:886-897 pubmed publisher
Mitchell A, Gray W, Hayek S, Ko Y, Thomas S, Rooney K, et al. Platelets confound the measurement of extracellular miRNA in archived plasma. Sci Rep. 2016;6:32651 pubmed publisher
Shi H, Yamamoto S, Sheng M, Bai J, Zhang P, Chen R, et al. ASXL1 plays an important role in erythropoiesis. Sci Rep. 2016;6:28789 pubmed publisher
Dabas R, Lee R, Servito M, Dharmani Khan P, Modi M, van Slyke T, et al. Antithymocyte Globulin at Clinically Relevant Concentrations Kills Leukemic Blasts. Biol Blood Marrow Transplant. 2016;22:815-24 pubmed publisher
Sponaas A, Moharrami N, Feyzi E, Standal T, Holth Rustad E, Waage A, et al. PDL1 Expression on Plasma and Dendritic Cells in Myeloma Bone Marrow Suggests Benefit of Targeted anti PD1-PDL1 Therapy. PLoS ONE. 2015;10:e0139867 pubmed publisher
Bai H, Liu Y, Xie Y, Hoyle D, Brodsky R, Cheng L, et al. Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells. J Cell Physiol. 2016;231:1065-76 pubmed publisher
Canver M, SMITH E, Sher F, Pinello L, Sanjana N, Shalem O, et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. 2015;527:192-7 pubmed publisher
Lee H, Gao X, Barrasa M, Li H, Elmes R, Peters L, et al. PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal. Nature. 2015;522:474-7 pubmed publisher
Tsiantoulas D, Perkmann T, Afonyushkin T, Mangold A, Prohaska T, Papac Milicevic N, et al. Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies. J Lipid Res. 2015;56:440-8 pubmed publisher
Ludwig L, Gazda H, Eng J, Eichhorn S, Thiru P, Ghazvinian R, et al. Altered translation of GATA1 in Diamond-Blackfan anemia. Nat Med. 2014;20:748-53 pubmed publisher
Zheng W, Dong X, Yin R, Xu F, Ning H, Zhang M, et al. EDAG positively regulates erythroid differentiation and modifies GATA1 acetylation through recruiting p300. Stem Cells. 2014;32:2278-89 pubmed publisher
Wu J, Zhou L, Yu W, Zhao Z, Xie X, Wang W, et al. PML4 facilitates erythroid differentiation by enhancing the transcriptional activity of GATA-1. Blood. 2014;123:261-70 pubmed publisher
Chang H, Wang T, Chen P, Lin Y, Liao C, Lin T, et al. Erythropoiesis suppression is associated with anthrax lethal toxin-mediated pathogenic progression. PLoS ONE. 2013;8:e71718 pubmed publisher
Ma Y, Wang B, Jiang F, Wang D, Liu H, Yan Y, et al. A feedback loop consisting of microRNA 23a/27a and the ?-like globin suppressors KLF3 and SP1 regulates globin gene expression. Mol Cell Biol. 2013;33:3994-4007 pubmed publisher
Alvarez Gonzalez C, Duggleby R, Vagaska B, Querol S, Gomez S, Ferretti P, et al. Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity. PLoS ONE. 2013;8:e67968 pubmed publisher
Sasaki H, Toda T, Furukawa T, Mawatari Y, Takaesu R, Shimizu M, et al. ?-1,6-Fucosyltransferase (FUT8) inhibits hemoglobin production during differentiation of murine and K562 human erythroleukemia cells. J Biol Chem. 2013;288:16839-47 pubmed publisher
Wong W, Sigvardsson M, Astrand Grundström I, Hogge D, Larsson J, Qian H, et al. Expression of integrin ?2 receptor in human cord blood CD34+CD38-CD90+ stem cells engrafting long-term in NOD/SCID-IL2R?(c) null mice. Stem Cells. 2013;31:360-71 pubmed publisher
Zhang X, Cruz F, Terry M, Remotti F, Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene. 2013;32:2249-60, 2260.e1-21 pubmed publisher
Danova Alt R, Heider A, Egger D, Cross M, Alt R. Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics. PLoS ONE. 2012;7:e34899 pubmed publisher
Landrigan A, Wong M, Utz P. CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanism. J Immunol. 2011;187:3033-43 pubmed publisher
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product information
Product Type :
Antibody
Product Name :
CD235a (Glycophorin A) Monoclonal Antibody (HIR2 (GA-R2)), PE, eBioscience™
Catalog # :
12-9987-82
Quantity :
100 µg
Price :
US 280
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 0.015 µg/test
Species :
Human
Clone :
HIR2 (GA-R2)
Isotype :
IgG2b, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
CD235a (Glycophorins A, GPA) is a single pass membrane sialoglycoprotein expressed in mature erythrocytes and erythroid precursor cells. CD235a is the carrier of blood group M and N specificities. CD235a provides cells with a large mucin-like that may serve as a barrier to cell fusion, minimizing aggregation between red blood cells in the circulation. CD235a has been shown to act as a receptor for Sandei virus, parvovirus, and Hsa, an Streptococcus adhesin.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.015 µg/test
Aliases :
AI853584; CD235; CD235a; erythroid-lineage-specific membrane sialoglycoprotein; glycophorin A; glycophorin A (MN blood group); glycophorin A (MNS blood group); glycophorin A, GPA; glycophorin Erik; glycophorin MiI; glycophorin MiV; glycophorin SAT; glycophorin Sta type C; glycophorin-A; GPA; GPErik; GPSAT; Gypa; HGNC:4702; HGpMiV; HGpMiX; HGpMiXI; HGpSta(C); HGpStaC; Mi.V glycoprotein; Mi.V glycoprotein (24 AA); MN; MN sialoglycoprotein; MNS; PAS-2; recombinant glycophorin A-B Miltenberger-DR; Sialoglycoprotein alpha
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA