Kappa Light Chain Monoclonal Antibody (TB28-2), PE, eBioscience | Invitrogen 12-9970-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Kappa Light Chain Monoclonal Antibody (TB28-2), PE, eBioscience

catalog :

12-9970-42

quantity :

100 Tests

price :

US 290.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

TB28-2

reactivity :

human

application :

flow cytometry

citations: 5

Reference
Ronsard L, Yousif A, Nait Mohamed F, Feldman J, Okonkwo V, McCarthy C, et al. Engaging an HIV vaccine target through the acquisition of low B cell affinity. Nat Commun. 2023;14:5249 pubmed publisher
Gasser P, Tarchevskaya S, Guntern P, Brigger D, Ruppli R, Zbären N, et al. The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab. Nat Commun. 2020;11:165 pubmed publisher
Weaver G, Villar R, Kanekiyo M, Nabel G, Mascola J, Lingwood D. In vitro reconstitution of B cell receptor-antigen interactions to evaluate potential vaccine candidates. Nat Protoc. 2016;11:193-213 pubmed publisher
Vauchy C, Gamonet C, Ferrand C, Daguindau E, Galaine J, Beziaud L, et al. CD20 alternative splicing isoform generates immunogenic CD4 helper T epitopes. Int J Cancer. 2015;137:116-26 pubmed publisher
Lingwood D, McTamney P, Yassine H, Whittle J, Guo X, Boyington J, et al. Structural and genetic basis for development of broadly neutralizing influenza antibodies. Nature. 2012;489:566-70 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Kappa Light Chain Monoclonal Antibody (TB28-2), PE, eBioscience

Catalog # :

12-9970-42

Quantity :

100 Tests

Price :

US 290.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.5 ug)/test

Species :

Human

Clone :

TB28-2

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains (kappa, lambda; both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. Antibodies to the kappa light chain are reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.5 ug)/test

Aliases :

D4Mit8; HCAK1; ig kappa chain c region; Igk; Igk@; Igkc; Igk-C; IGKCD; IGKV; IGKV15; IGKV1-5; Immunoglobulin K; immunoglobulin kappa chain complex; immunoglobulin kappa constant; immunoglobulin kappa light chain; immunoglobulin kappa locus; immunoglobulin kappa variable 1-5; kappa; Kappa LC; Km; L12; L12a; LOC500183; similar to NGF-binding Ig light chain; V1