HLA-G Monoclonal Antibody (87G), PE, eBioscience™ | Invitrogen 12-9957-41 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HLA-G Monoclonal Antibody (87G), PE, eBioscience™

catalog :

12-9957-41

quantity :

25 Tests

price :

US 163

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

87G

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Aghababaei M, Hogg K, Perdu S, Robinson W, Beristain A. ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion. Cell Death Differ. 2015;22:1970-84 pubmed publisher
	Todorova D, Zhang Y, Chen Q, Liu J, He J, Fu X, et al. hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts. EBioMedicine. 2020;62:103120 pubmed publisher
	Ma Y, Yang Q, Fan M, Zhang L, Gu Y, Jia W, et al. Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation. Cell Prolif. 2020;53:e12802 pubmed publisher
	Fuchi N, Miura K, Doi H, Li T, Masuzaki H. Feasibility of placenta-derived mesenchymal stem cells as a tool for studying pregnancy-related disorders. Sci Rep. 2017;7:46220 pubmed publisher
	Hoya Arias R, Tomishima M, Perna F, Voza F, Nimer S. L3MBTL1 deficiency directs the differentiation of human embryonic stem cells toward trophectoderm. Stem Cells Dev. 2011;20:1889-900 pubmed publisher
	Carosella E, Favier B, Rouas Freiss N, Moreau P, Lemaoult J. Beyond the increasing complexity of the immunomodulatory HLA-G molecule. Blood. 2008;111:4862-70 pubmed publisher
	Rouas Freiss N, Moreau P, Menier C, Carosella E. HLA-G in cancer: a way to turn off the immune system. Semin Cancer Biol. 2003;13:325-36 pubmed
	Ishitani A, Sageshima N, Lee N, Dorofeeva N, Hatake K, Marquardt H, et al. Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition. J Immunol. 2003;171:1376-84 pubmed
	Paul P, Rouas Freiss N, Moreau P, Cabestre F, Menier C, Khalil Daher I, et al. HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression. Hum Immunol. 2000;61:1177-95 pubmed
	Onno M, Le Friec G, Pangault C, Amiot L, Guilloux V, Drenou B, et al. Modulation of HLA-G antigens expression in myelomonocytic cells. Hum Immunol. 2000;61:1086-94 pubmed
	Yang Y, Chu W, Geraghty D, Hunt J. Expression of HLA-G in human mononuclear phagocytes and selective induction by IFN-gamma. J Immunol. 1996;156:4224-31 pubmed
	Odum N, Ledbetter J, Martin P, Geraghty D, Tsu T, Hansen J, et al. Homotypic aggregation of human cell lines by HLA class II-, class Ia- and HLA-G-specific monoclonal antibodies. Eur J Immunol. 1991;21:2121-31 pubmed

product information

Product Type :

Antibody

Product Name :

HLA-G Monoclonal Antibody (87G), PE, eBioscience™

Catalog # :

12-9957-41

Quantity :

25 Tests

Price :

US 163

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

87G

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

b2 microglobulin; DADB-15K14.8; HLA class I histocompatibility antigen, alpha chain G; HLA class I molecule; HLA G antigen; HLA-6.0; HLAG; HLA-G; HLA-G histocompatibility antigen, class I, G; major histocompatibility complex, class I, G; MHC class I antigen G; MHC-G; sHLA-G; Soluble HLA class I histocompatibility antigen, alpha chain G

more info or order :

Invitrogen product webpage