CD371 (Clec12A) Monoclonal Antibody (HB3), PE, eBioscience | Invitrogen 12-9878-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD371 (Clec12A) Monoclonal Antibody (HB3), PE, eBioscience

catalog :

12-9878-41

quantity :

25 Tests

price :

US 146.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

HB3

reactivity :

human

application :

flow cytometry

citations: 4

Reference
Xu Y, Song D, Wang W, Li S, Yue T, Xia T, et al. Clec12a inhibits MSU-induced immune activation through lipid raft expulsion. Life Sci Alliance. 2023;6: pubmed publisher
Lahoud M, Proietto A, Ahmet F, Kitsoulis S, Eidsmo L, Wu L, et al. The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses. J Immunol. 2009;182:7587-94 pubmed publisher
Marshall A, Willment J, Pyz E, Dennehy K, Reid D, Dri P, et al. Human MICL (CLEC12A) is differentially glycosylated and is down-regulated following cellular activation. Eur J Immunol. 2006;36:2159-69 pubmed
Marshall A, Willment J, Lin H, Williams D, Gordon S, Brown G. Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J Biol Chem. 2004;279:14792-802 pubmed

product information

Product Type :

Antibody

Product Name :

CD371 (Clec12A) Monoclonal Antibody (HB3), PE, eBioscience

Catalog # :

12-9878-41

Quantity :

25 Tests

Price :

US 146.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

HB3

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD371 is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

CD371; Clec12a; CLL1; CLL-1; C-type lectin domain family 12 member A; C-type lectin domain family 12, member A; C-type lectin protein CLL-1; C-type lectin-like molecule 1; C-type lectin-like molecule-1; D230024O04; DCAL2; DCAL-2; Dendritic cell-associated lectin 2; KLRL1; Micl; Myeloid inhibitory C-type lectin-like receptor