This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
LAP (Latency Associated peptide) Monoclonal Antibody (TW7-16B4), PE, eBioscience
catalog :
12-9821-82
quantity :
100 ug
price :
US 344.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
TW7-16B4

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 6
Reference
Medina Buelvas D, Rodr xed guez Sosa M, Vega L. Characterisation of Macrophage Polarisation in Mice Infected with Ninoa Strain of Trypanosoma cruzi. Pathogens. 2021;10: pubmed publisher
Thevenot P, Saravia J, Giaimo J, Happel K, Dugas T, Cormier S. Chronic alcohol induces M2 polarization enhancing pulmonary disease caused by exposure to particulate air pollution. Alcohol Clin Exp Res. 2013;37:1910-9 pubmed publisher
Edwards J, Fujii H, Zhou A, Creemers J, Unutmaz D, Shevach E. Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation. J Immunol. 2013;190:5506-15 pubmed publisher
Oida T, Weiner H. TGF-? induces surface LAP expression on murine CD4 T cells independent of Foxp3 induction. PLoS ONE. 2010;5:e15523 pubmed publisher
Mantel P, Schmidt Weber C. Transforming growth factor-beta: recent advances on its role in immune tolerance. Methods Mol Biol. 2011;677:303-38 pubmed publisher
Tran D, Andersson J, Wang R, Ramsey H, Unutmaz D, Shevach E. GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci U S A. 2009;106:13445-50 pubmed publisher
product information
Product Type :
Antibody
Product Name :
LAP (Latency Associated peptide) Monoclonal Antibody (TW7-16B4), PE, eBioscience
Catalog # :
12-9821-82
Quantity :
100 ug
Price :
US 344.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 ug/test
Species :
Mouse
Clone :
TW7-16B4
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines, found almost ubiquitously in tissues. Transforming growth factor (TGF)-b is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein, known as LTBP.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 ug/test
Aliases :
CED; DPD1; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; Tgfb1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA