EVA1 Monoclonal Antibody (G9P3-1), PE, eBioscience | Invitrogen 12-9742-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

EVA1 Monoclonal Antibody (G9P3-1), PE, eBioscience

catalog :

12-9742-82

quantity :

100 ug

price :

US 441.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

G9P3-1

reactivity :

human, mouse

application :

flow cytometry

citations: 3

Reference
Garabatos N, Blanco J, Fandos C, Lopez E, Santamaria P, Ruiz A, et al. A monoclonal antibody against the extracellular domain of mouse and human epithelial V-like antigen 1 reveals a restricted expression pattern among CD4- CD8- thymocytes. Monoclon Antib Immunodiagn Immunother. 2014;33:305-11 pubmed publisher
Iacovelli S, Iosue I, Di Cesare S, Guttinger M. Lymphoid EVA1 expression is required for DN1-DN3 thymocytes transition. PLoS ONE. 2009;4:e7586 pubmed publisher
Tydell C, David Fung E, Moore J, Rowen L, Taghon T, Rothenberg E. Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J Immunol. 2007;179:421-38 pubmed

product information

Product Type :

Antibody

Product Name :

EVA1 Monoclonal Antibody (G9P3-1), PE, eBioscience

Catalog # :

12-9742-82

Quantity :

100 ug

Price :

US 441.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 0.5 ug/test

Species :

Human, Mouse

Clone :

G9P3-1

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test

Aliases :

epithelial V-like antigen 1; EVA; Eva1; MPZL2; myelin protein zero like 2; myelin protein zero-like 2; myelin protein zero-like protein 2; UNQ606/PRO1192