product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ly-6G Monoclonal Antibody (1A8-Ly6g), PE, eBioscience
catalog :
12-9668-82
quantity :
100 µg
price :
US 341
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
1A8-Ly6g
reactivity :
mouse
application :
flow cytometry, blocking or activating experiments
more info or order :
citations: 32
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig s3h
Chu C, Murdock M, Jing D, Won T, Chung H, Kressel A, et al. The microbiota regulate neuronal function and fear extinction learning. Nature. 2019;574:543-548 pubmed publisher
  • blocking or activating experiments; mouse; loading ...; fig s4a
Nishi H, Furuhashi K, Cullere X, Saggu G, Miller M, Chen Y, et al. Neutrophil Fc?RIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. J Clin Invest. 2017;127:3810-3826 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Briseño C, Gargaro M, Durai V, Davidson J, Theisen D, Anderson D, et al. Deficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms. Proc Natl Acad Sci U S A. 2017;114:3957-3962 pubmed publisher
Xu S, Bian H, Shu S, Xia S, Gu Y, Zhang M, et al. AIM2 deletion enhances blood-brain barrier integrity in experimental ischemic stroke. CNS Neurosci Ther. 2021;27:1224-1237 pubmed publisher
Vijayaraj S, Feltham R, Rashidi M, Frank D, Liu Z, Simpson D, et al. The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation. Nat Commun. 2021;12:2713 pubmed publisher
Rubinstein L, Paul A, Houseman C, Abegaz M, Tabares Ruiz S, O Neil N, et al. Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness. Cells. 2021;10: pubmed publisher
Iizasa E, Chuma Y, Uematsu T, Kubota M, Kawaguchi H, Umemura M, et al. TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation. Nat Commun. 2021;12:2299 pubmed publisher
Nuti E, Rossello A, Cuffaro D, Camodeca C, Van Bael J, van der Maat D, et al. Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms. Cells. 2020;9: pubmed publisher
Gong Y, Zhang Y, Wang Z, Song H, Liu Y, Lv A, et al. Tanshinone IIA alleviates brain damage in a mouse model of neuromyelitis optica spectrum disorder by inducing neutrophil apoptosis. J Neuroinflammation. 2020;17:198 pubmed publisher
Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, et al. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke. Nat Commun. 2020;11:2488 pubmed publisher
Mulas F, Wang X, Song S, Nishanth G, Yi W, Brunn A, et al. The deubiquitinase OTUB1 augments NF-κB-dependent immune responses in dendritic cells in infection and inflammation by stabilizing UBC13. Cell Mol Immunol. 2020;: pubmed publisher
Liu P, Zhao L, Loos F, Marty C, Xie W, Martins I, et al. Immunosuppression by Mutated Calreticulin Released from Malignant Cells. Mol Cell. 2019;: pubmed publisher
Manolova V, Nyffenegger N, Flace A, Altermatt P, Varol A, Doucerain C, et al. Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia. J Clin Invest. 2019;130:491-506 pubmed publisher
Li C, Zeng Q, Chen M, Xu L, Zhang C, Mai F, et al. Evodiamine Augments NLRP3 Inflammasome Activation and Anti-bacterial Responses Through Inducing α-Tubulin Acetylation. Front Pharmacol. 2019;10:290 pubmed publisher
Stokes K, Cortez Retamozo V, Acosta J, Lauderback B, Robles Oteiza C, Cicchini M, et al. Natural killer cells limit the clearance of senescent lung adenocarcinoma cells. Oncogenesis. 2019;8:24 pubmed publisher
Zhang C, Ye S, Ni J, Cai T, Liu Y, Huang D, et al. STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion. Cell Death Differ. 2019;: pubmed publisher
Gawish R, Bulat T, Biaggio M, Lassnig C, Bago Horvath Z, Macho Maschler S, et al. Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1. Cell Rep. 2019;26:2394-2406.e5 pubmed publisher
Vandermosten L, Pham T, Knoops S, De Geest C, Lays N, Van der Molen K, et al. Adrenal hormones mediate disease tolerance in malaria. Nat Commun. 2018;9:4525 pubmed publisher
Araujo A, Antunes M, Mattos M, Diniz A, Alvarenga D, Nakagaki B, et al. Liver Immune Cells Release Type 1 Interferon Due to DNA Sensing and Amplify Liver Injury from Acetaminophen Overdose. Cells. 2018;7: pubmed publisher
Moschovakis G, Bubke A, Friedrichsen M, Ristenpart J, Back J, Falk C, et al. The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy. Cell Mol Immunol. 2018;: pubmed publisher
Ritzel R, Lai Y, Crapser J, Patel A, Schrecengost A, Grenier J, et al. Aging alters the immunological response to ischemic stroke. Acta Neuropathol. 2018;136:89-110 pubmed publisher
Mei Y, Feng G, Rahimi N, Zhao B, Zhang J, Cao L, et al. Loss of mDia1 causes neutropenia via attenuated CD11b endocytosis and increased neutrophil adhesion to the endothelium. Blood Adv. 2017;1:1650-1656 pubmed publisher
Zha Q, Wei H, Li C, Liang Y, Xu L, Bai W, et al. ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages. Front Immunol. 2016;7:597 pubmed publisher
Perobelli S, Mercadante A, Galvani R, Gonçalves Silva T, Alves A, Pereira Neves A, et al. G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way. J Immunol. 2016;197:3725-3734 pubmed
van der Velden D, Lagraauw H, Wezel A, Launay P, Kuiper J, Huizinga T, et al. Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile. Arthritis Res Ther. 2016;18:138 pubmed publisher
Michlmayr D, Bardina S, Rodriguez C, Pletnev A, Lim J. Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance. J Immunol. 2016;196:4622-31 pubmed publisher
Patnode M, Cheng C, Chou C, Singer M, Elin M, Uchimura K, et al. Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue. J Biol Chem. 2013;288:26533-45 pubmed publisher
von Brühl M, Stark K, Steinhart A, Chandraratne S, Konrad I, Lorenz M, et al. Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med. 2012;209:819-35 pubmed publisher
Ribeiro Gomes F, Peters N, Debrabant A, Sacks D. Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response. PLoS Pathog. 2012;8:e1002536 pubmed publisher
Frazer L, O Connell C, Andrews C, Zurenski M, Darville T. Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection. Infect Immun. 2011;79:4029-41 pubmed publisher
Carrigan S, Junkins R, Yang Y, MacNeil A, Richardson C, Johnston B, et al. IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice. J Immunol. 2010;185:3602-9 pubmed publisher
Charmoy M, Brunner Agten S, Aebischer D, Auderset F, Launois P, Milon G, et al. Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice. PLoS Pathog. 2010;6:e1000755 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Ly-6G Monoclonal Antibody (1A8-Ly6g), PE, eBioscience
Catalog # :
12-9668-82
Quantity :
100 µg
Price :
US 341
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.125 µg/test
Species :
Mouse
Clone :
1A8-Ly6g
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
Ly6G (Lymphocyte antigen 6 complex locus G6D) is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. The Ly6G protein has a molecular weight of approximately 21-25 kDa and is expressed by myeloid derived cells in the bone marrow. Ly6G is a good marker for detection of peripheral neutrophils, monocytes and granulocytes. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. The physiological role of Ly6G remains unclear but studies have shown its involvement in anti-tumor response, and studies with neutrophils suggest that Ly6G ligation may have an inhibitory effect on local immune responses.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.125 µg/test
Aliases :
Gr1; Gr-1; Ly6g; Ly-6G; ly-6G.1; lymphocyte antigen 6 complex, locus G; lymphocyte antigen 6G
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA