TIGIT Monoclonal Antibody (GIGD7), PE, eBioscience | Invitrogen 12-9501-80 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TIGIT Monoclonal Antibody (GIGD7), PE, eBioscience

catalog :

12-9501-80

quantity :

25 µg

price :

US 163

clonality :

monoclonal

host :

rat

conjugate :

clone name :

GIGD7

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2b	Kurtulus S, Sakuishi K, Ngiow S, Joller N, Tan D, Teng M, et al. TIGIT predominantly regulates the immune response via regulatory T cells. J Clin Invest. 2015;125:4053-62 pubmed publisher
flow cytometry; mouse; fig 3	Thiault N, Darrigues J, Adoue V, Gros M, Binet B, Pérals C, et al. Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors. Nat Immunol. 2015;16:628-34 pubmed publisher
	Chen X, MacNabb B, Flood B, Blazar B, Kline J. Divergent fates of antigen-specific CD8+ T cell clones in mice with acute leukemia. Cell Rep. 2021;37:109991 pubmed publisher
	Srivastava R, Khan A, Chilukuri S, Syed S, Tran T, Furness J, et al. CXCL10/CXCR3-Dependent Mobilization of Herpes Simplex Virus-Specific CD8+ TEM and CD8+ TRM Cells within Infected Tissues Allows Efficient Protection against Recurrent Herpesvirus Infection and Disease. J Virol. 2017;91: pubmed publisher
	Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific Î³Î´ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
	Koyama M, Kuns R, Olver S, Lineburg K, Lor M, Teal B, et al. Promoting regulation via the inhibition of DNAM-1 after transplantation. Blood. 2013;121:3511-20 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TIGIT Monoclonal Antibody (GIGD7), PE, eBioscience

Catalog # :

12-9501-80

Quantity :

25 µg

Price :

US 163

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 µg/test

Species :

Mouse

Clone :

GIGD7

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Immunogen :

mTIGIT-Fc treated with 4% PFA

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM

more info or order :

Invitrogen product webpage