product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD289 (TLR9) Monoclonal Antibody (eB72-1665), PE, eBioscience
catalog :
12-9099-82
quantity :
100 µg
price :
US 423
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
eB72-1665
reactivity :
human
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 32
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1d
Deeba E, Lambrianides A, Pantzaris M, Krashias G, Christodoulou C. The expression profile of virus-recognizing toll-like receptors in natural killer cells of Cypriot multiple sclerosis patients. BMC Res Notes. 2020;13:460 pubmed publisher
  • flow cytometry; human; fig 1, 2, 3
Bratke K, Klein C, Kuepper M, Lommatzsch M, Virchow J. Differential development of plasmacytoid dendritic cells in Th1- and Th2-like cytokine milieus. Allergy. 2011;66:386-95 pubmed publisher
Aillot L, Bonnin M, Ait Goughoulte M, Bendriss Vermare N, Maadadi S, Dimier L, et al. Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells. Antimicrob Agents Chemother. 2018;62: pubmed publisher
Tobouti P, BOLT R, Radhakrishnan R, de Sousa S, Hunter K. Altered Toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma. Oncotarget. 2018;9:236-248 pubmed publisher
El Kebir D, Damlaj A, Makhezer N, Filep J. Toll-like receptor 9 signaling regulates tissue factor and tissue factor pathway inhibitor expression in human endothelial cells and coagulation in mice. Crit Care Med. 2015;43:e179-89 pubmed publisher
El Kebir D, Damlaj A, Filep J. Toll-like receptor 9 signaling delays neutrophil apoptosis by increasing transcription of Mcl-1. PLoS ONE. 2014;9:e87006 pubmed publisher
Bratke K, Prieschenk C, Garbe K, Kuepper M, Lommatzsch M, Virchow J. Plasmacytoid dendritic cells in allergic asthma and the role of inhaled corticosteroid treatment. Clin Exp Allergy. 2013;43:312-21 pubmed publisher
Freeman C, Martinez F, Han M, Washko G, McCubbrey A, Chensue S, et al. Lung CD8+ T cells in COPD have increased expression of bacterial TLRs. Respir Res. 2013;14:13 pubmed publisher
Fierro M, Banche G, Marenco F, Novelli M, Allizond V, Mandras N, et al. Functional and phenotypical impairment of polymorphonuclear cells in atopic dermatitis: an additional cause for the known susceptibility to infections?. Dermatology. 2012;224:323-30 pubmed publisher
Garbe K, Bratke K, Wagner S, Virchow J, Lommatzsch M. Plasmacytoid dendritic cells and their Toll-like receptor 9 expression selectively decrease with age. Hum Immunol. 2012;73:493-7 pubmed publisher
Fierro M, Cuffini A, Novelli M, Banche G, Allizond V, Comessatti A, et al. Functional and phenotypical alterations of polymorphonuclear cells in Sézary syndrome patients. Eur J Dermatol. 2011;21:921-9 pubmed publisher
Dasari P, Zola H, Nicholson I. Expression of Toll-like receptors by neonatal leukocytes. Pediatr Allergy Immunol. 2011;22:221-8 pubmed publisher
Llinàs L, Lázaro A, de Salort J, Matesanz Isabel J, Sintes J, Engel P. Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry. Immunol Lett. 2011;134:113-21 pubmed publisher
Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher
Kiemer A, Senaratne R, Hoppstädter J, Diesel B, Riley L, Tabeta K, et al. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun. 2009;1:29-45 pubmed publisher
Liu F, Li G, Wen K, Bui T, Cao D, Zhang Y, et al. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunol. 2010;23:135-49 pubmed publisher
Neves P, Matos D, Marcovistz R, Galler R. TLR expression and NK cell activation after human yellow fever vaccination. Vaccine. 2009;27:5543-9 pubmed publisher
Zorro S, Arias M, Riano F, Paris S, Ramirez L, Uribe O, et al. Response to ODN-CpG by B Cells from patients with systemic lupus erythematosus correlates with disease activity. Lupus. 2009;18:718-26 pubmed publisher
Martín Martín L, Almeida J, Hernández Campo P, Sanchez M, Lecrevisse Q, Orfao A. Immunophenotypical, morphologic, and functional characterization of maturation-associated plasmacytoid dendritic cell subsets in normal adult human bone marrow. Transfusion. 2009;49:1692-1708 pubmed publisher
El Kebir D, Jozsef L, Pan W, Wang L, Filep J. Bacterial DNA activates endothelial cells and promotes neutrophil adherence through TLR9 signaling. J Immunol. 2009;182:4386-94 pubmed publisher
Wen K, Azevedo M, Gonzalez A, Zhang W, Saif L, Li G, et al. Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs. Vet Immunol Immunopathol. 2009;127:304-15 pubmed publisher
Peiser M, Koeck J, Kirschning C, Wittig B, Wanner R. Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol. 2008;83:1118-27 pubmed publisher
Loharungsikul S, Troye Blomberg M, Amoudruz P, Pichyangkul S, Yongvanitchit K, Looareesuwan S, et al. Expression of toll-like receptors on antigen-presenting cells in patients with falciparum malaria. Acta Trop. 2008;105:10-5 pubmed
Papadimitraki E, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, et al. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum. 2006;54:3601-11 pubmed
Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
Leifer C, Brooks J, Hoelzer K, Lopez J, Kennedy M, Mazzoni A, et al. Cytoplasmic targeting motifs control localization of toll-like receptor 9. J Biol Chem. 2006;281:35585-92 pubmed
Jozsef L, Khreiss T, El Kebir D, Filep J. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol. 2006;176:1195-202 pubmed
Schroeder J, Bieneman A, Xiao H, Chichester K, Vasagar K, Saini S, et al. TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression. J Immunol. 2005;175:5724-31 pubmed
Dasari P, Nicholson I, Hodge G, Dandie G, Zola H. Expression of toll-like receptors on B lymphocytes. Cell Immunol. 2005;236:140-5 pubmed
Droemann D, Albrecht D, Gerdes J, Ulmer A, Branscheid D, Vollmer E, et al. Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res. 2005;6:1 pubmed
Eaton Bassiri A, Dillon S, Cunningham M, Rycyzyn M, Mills J, Sarisky R, et al. Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells. Infect Immun. 2004;72:7202-11 pubmed
Leifer C, Kennedy M, Mazzoni A, Lee C, Kruhlak M, Segal D. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol. 2004;173:1179-83 pubmed
product information
Product Type :
Antibody
Product Name :
CD289 (TLR9) Monoclonal Antibody (eB72-1665), PE, eBioscience
Catalog # :
12-9099-82
Quantity :
100 µg
Price :
US 423
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human
Applications :
Flow Cytometry: 1 µg/test
Species :
Human
Clone :
eB72-1665
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 µg/test
Aliases :
CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA