CD289 (TLR9) Monoclonal Antibody (eB72-1665), PE, eBioscience™ | Invitrogen 12-9099-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD289 (TLR9) Monoclonal Antibody (eB72-1665), PE, eBioscience™

catalog :

12-9099-80

quantity :

25 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eB72-1665

reactivity :

human

application :

flow cytometry

citations: 13

Reference
Aillot L, Bonnin M, Ait Goughoulte M, Bendriss Vermare N, Maadadi S, Dimier L, et al. Interaction between Toll-Like Receptor 9-CpG Oligodeoxynucleotides and Hepatitis B Virus Virions Leads to Entry Inhibition in Hepatocytes and Reduction of Alpha Interferon Production by Plasmacytoid Dendritic Cells. Antimicrob Agents Chemother. 2018;62: pubmed publisher
Tobouti P, BOLT R, Radhakrishnan R, de Sousa S, Hunter K. Altered Toll-like receptor expression and function in HPV-associated oropharyngeal carcinoma. Oncotarget. 2018;9:236-248 pubmed publisher
El Kebir D, Damlaj A, Makhezer N, Filep J. Toll-like receptor 9 signaling regulates tissue factor and tissue factor pathway inhibitor expression in human endothelial cells and coagulation in mice. Crit Care Med. 2015;43:e179-89 pubmed publisher
Liu F, Li G, Wen K, Bui T, Cao D, Zhang Y, et al. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunol. 2010;23:135-49 pubmed publisher
El Kebir D, Jozsef L, Pan W, Wang L, Filep J. Bacterial DNA activates endothelial cells and promotes neutrophil adherence through TLR9 signaling. J Immunol. 2009;182:4386-94 pubmed publisher
Wen K, Azevedo M, Gonzalez A, Zhang W, Saif L, Li G, et al. Toll-like receptor and innate cytokine responses induced by lactobacilli colonization and human rotavirus infection in gnotobiotic pigs. Vet Immunol Immunopathol. 2009;127:304-15 pubmed publisher
Peiser M, Koeck J, Kirschning C, Wittig B, Wanner R. Human Langerhans cells selectively activated via Toll-like receptor 2 agonists acquire migratory and CD4+T cell stimulatory capacity. J Leukoc Biol. 2008;83:1118-27 pubmed publisher
Papadimitraki E, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, et al. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum. 2006;54:3601-11 pubmed
Peduzzi E, Groeper C, Schütte D, Zajac P, Rondini S, Mensah Quainoo E, et al. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 2007;127:638-45 pubmed
Jozsef L, Khreiss T, El Kebir D, Filep J. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol. 2006;176:1195-202 pubmed
Schroeder J, Bieneman A, Xiao H, Chichester K, Vasagar K, Saini S, et al. TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression. J Immunol. 2005;175:5724-31 pubmed
Dasari P, Nicholson I, Hodge G, Dandie G, Zola H. Expression of toll-like receptors on B lymphocytes. Cell Immunol. 2005;236:140-5 pubmed
Eaton Bassiri A, Dillon S, Cunningham M, Rycyzyn M, Mills J, Sarisky R, et al. Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells. Infect Immun. 2004;72:7202-11 pubmed

product information

Product Type :

Antibody

Product Name :

CD289 (TLR9) Monoclonal Antibody (eB72-1665), PE, eBioscience™

Catalog # :

12-9099-80

Quantity :

25 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 1 µg/test

Species :

Human

Clone :

eB72-1665

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 µg/test

Aliases :

CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605