Phospho-Syk (Tyr348) Monoclonal Antibody (moch1ct), PE, eBioscience | Invitrogen 12-9014-41 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Syk (Tyr348) Monoclonal Antibody (moch1ct), PE, eBioscience

catalog :

12-9014-41

quantity :

25 Tests

price :

US 156

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

moch1ct

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1h	Greco S, Torres Hernandez A, Kalabin A, Whiteman C, Rokosh R, Ravirala S, et al. Mincle Signaling Promotes Con A Hepatitis. J Immunol. 2016;197:2816-27 pubmed publisher
flow cytometry; mouse; loading ...; fig s7a	Seifert L, Werba G, Tiwari S, Giao Ly N, Alothman S, Alqunaibit D, et al. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature. 2016;532:245-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-Syk (Tyr348) Monoclonal Antibody (moch1ct), PE, eBioscience

Catalog # :

12-9014-41

Quantity :

25 Tests

Price :

US 156

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 5 µL (0.06 µg)/test

Species :

Human, Mouse

Clone :

moch1ct

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Syk is a cytoplasmic protein tyrosine kinase that translocates to the plasma membrane upon B cell antigen receptor (BCR) or the high-affinity IgE receptor (FcepsilonRI) triggering, and phosphorylates downstream adaptor proteins, thereby providing docking sites for initiation of subsequent signaling pathways, such as calcium mobilization, cytoskeleton remodeling, or transcription of specific genes. Syk binds to the receptor assemblies through interactions of its pair of SH2 domains with ITAM motives of the receptor, which have been phosphorylated by Src-family kinases. These kinases also help to activate Syk by phosphorylation of its activation loop.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.06 µg)/test

Aliases :

DKFZp313N1010; EC 2.7.10.2; FLJ25043; FLJ37489; HGNC:11205; kinase Syk; KSYK; p72Syk; p72-Syk; ptk72; SP1; spleen associated tyrosine kinase; spleen tyrosine kinase; SYK; syk signaling; Sykb; tyrosine-kinase syk; tyrosine-protein kinase SYK

more info or order :

Invitrogen product webpage