CD281 (TLR1) Monoclonal Antibody (eBioTR23 (TR23)), PE, eBioscience | Invitrogen 12-9011-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD281 (TLR1) Monoclonal Antibody (eBioTR23 (TR23)), PE, eBioscience

catalog :

12-9011-80

quantity :

25 ug

price :

US 212.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBioTR23 (TR23)

reactivity :

mouse

application :

flow cytometry

citations: 14

Reference
Xu Y, Liu E, Xie X, Wang J, Zheng H, Ju Y, et al. Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases. iScience. 2021;24:103445 pubmed publisher
Huang Y, Zhang B, Haneke H, Haage V, Lubas M, Yuan Y, et al. Glial cell line-derived neurotrophic factor increases matrix metallopeptidase 9 and 14 expression in microglia and promotes microglia-mediated glioma progression. J Neurosci Res. 2021;99:1048-1063 pubmed publisher
Patidar A, Selvaraj S, Chauhan P, Guzman C, Ebensen T, Sarkar A, et al. Peptidoglycan-treated tumor antigen-pulsed dendritic cells impart complete resistance against tumor rechallenge. Clin Exp Immunol. 2020;201:279-288 pubmed publisher
Matsuoka S, Hashimoto D, Kadowaki M, Ohigashi H, Hayase E, Yokoyama E, et al. The myeloid differentiation factor 88 signaling in donor T cells accelerates graft-versus-host disease. Haematologica. 2019;: pubmed publisher
Raj D, Yin Z, Breur M, Doorduin J, Holtman I, Olah M, et al. Increased White Matter Inflammation in Aging- and Alzheimer's Disease Brain. Front Mol Neurosci. 2017;10:206 pubmed publisher
Corbitt N, Kimura S, Isse K, Specht S, Chedwick L, Rosborough B, et al. Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation. Am J Pathol. 2013;182:180-91 pubmed publisher
Oakes J, O Connor B, Warg L, Burton R, Hock A, Loader J, et al. Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist. Am J Respir Cell Mol Biol. 2013;48:27-34 pubmed publisher
Boyd A, Shivshankar P, Jiang S, Berton M, Orihuela C. Age-related defects in TLR2 signaling diminish the cytokine response by alveolar macrophages during murine pneumococcal pneumonia. Exp Gerontol. 2012;47:507-18 pubmed publisher
Kobayashi F, Watanabe E, Nakagawa Y, Yamanishi S, Norose Y, Fukunaga Y, et al. Production of autoantibodies by murine B-1a cells stimulated with Helicobacter pylori urease through toll-like receptor 2 signaling. Infect Immun. 2011;79:4791-801 pubmed publisher
Miranda Hernandez S, Gerlach N, Fletcher J, Biros E, Mack M, Korner H, et al. Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. J Immunol. 2011;187:791-804 pubmed publisher
Burton O, Gibbs S, Miller N, Jones F, Wen L, Dunne D, et al. Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens. Eur J Immunol. 2010;40:2221-9 pubmed publisher
Segura E, Kapp E, Gupta N, Wong J, Lim J, Ji H, et al. Differential expression of pathogen-recognition molecules between dendritic cell subsets revealed by plasma membrane proteomic analysis. Mol Immunol. 2010;47:1765-73 pubmed publisher
Asprodites N, Zheng L, Geng D, Velasco Gonzalez C, Sanchez Perez L, Davila E. Engagement of Toll-like receptor-2 on cytotoxic T-lymphocytes occurs in vivo and augments antitumor activity. FASEB J. 2008;22:3628-37 pubmed publisher
Vallois D, Grimm C, Avner P, Boitard C, Rogner U. The type 1 diabetes locus Idd6 controls TLR1 expression. J Immunol. 2007;179:3896-903 pubmed

product information

Product Type :

Antibody

Product Name :

CD281 (TLR1) Monoclonal Antibody (eBioTR23 (TR23)), PE, eBioscience

Catalog # :

12-9011-80

Quantity :

25 ug

Price :

US 212.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 ug/test

Species :

Mouse

Clone :

eBioTR23 (TR23)

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

TLR1 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and co-expression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several tri-acylated lipopeptides. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for the TLR1 gene.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test

Aliases :

CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1