Granulysin Monoclonal Antibody (eBioDH2 (DH2)), PE, eBioscience | Invitrogen 12-8828-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Granulysin Monoclonal Antibody (eBioDH2 (DH2)), PE, eBioscience

catalog :

12-8828-42

quantity :

100 Tests

price :

US 343.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

eBioDH2 (DH2)

reactivity :

human

application :

flow cytometry

citations: 8

Reference
Pi J, Zhang Z, Yang E, Chen L, Zeng L, Chen Y, et al. Nanocages engineered from Bacillus Calmette-Guerin facilitate protective Vγ2Vδ2 T cell immunity against Mycobacterium tuberculosis infection. J Nanobiotechnology. 2022;20:36 pubmed publisher
Kathamuthu G, Kumar N, Moideen K, Menon P, Babu S. Decreased Frequencies of Gamma/Delta T Cells Expressing Th1/Th17 Cytokine, Cytotoxic, and Immune Markers in Latent Tuberculosis-Diabetes/Pre-Diabetes Comorbidity. Front Cell Infect Microbiol. 2021;11:756854 pubmed publisher
Fletcher H, Filali Mouhim A, Nemes E, Hawkridge A, Keyser A, Njikan S, et al. Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study. BMC Med. 2016;14:76 pubmed publisher
Tilburgs T, Schonkeren D, Eikmans M, Nagtzaam N, Datema G, Swings G, et al. Human decidual tissue contains differentiated CD8+ effector-memory T cells with unique properties. J Immunol. 2010;185:4470-7 pubmed publisher
Spencer C, Abate G, Blazevic A, Hoft D. Only a subset of phosphoantigen-responsive gamma9delta2 T cells mediate protective tuberculosis immunity. J Immunol. 2008;181:4471-84 pubmed
Gansert J, Kiessler V, Engele M, Wittke F, Rollinghoff M, Krensky A, et al. Human NKT cells express granulysin and exhibit antimycobacterial activity. J Immunol. 2003;170:3154-61 pubmed
Ochoa M, Stenger S, Sieling P, Thoma Uszynski S, Sabet S, Cho S, et al. T-cell release of granulysin contributes to host defense in leprosy. Nat Med. 2001;7:174-9 pubmed
Hanson D, Kaspar A, Poulain F, Krensky A. Biosynthesis of granulysin, a novel cytolytic molecule. Mol Immunol. 1999;36:413-22 pubmed

product information

Product Type :

Antibody

Product Name :

Granulysin Monoclonal Antibody (eBioDH2 (DH2)), PE, eBioscience

Catalog # :

12-8828-42

Quantity :

100 Tests

Price :

US 343.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

eBioDH2 (DH2)

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

GNLY is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. GNLY is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

D2S69E; GNLY; Granulysin; LAG2; LAG-2; lymphocyte-activation gene 2; Lymphokine; lymphokine LAG-2; Lymphokine NKG5519; NKG5; Protein NKG5; T-cell activation protein 519; TLA519; T-lymphocyte activation gene 519