CD217 (IL-17Ra) Monoclonal Antibody (J10MBS), PE, eBioscience | Invitrogen 12-7517-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD217 (IL-17Ra) Monoclonal Antibody (J10MBS), PE, eBioscience

catalog :

12-7517-42

quantity :

100 Tests

price :

US 397.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

J10MBS

reactivity :

human

application :

flow cytometry

citations: 7

Reference
He J, Xu Y, Yi M, Gu C, Zhu Y, Hu G. Involvement of natural killer cells in the pathogenesis of endometriosis in patients with pelvic pain. J Int Med Res. 2020;48:300060519871407 pubmed publisher
Maione F, Cicala C, Liverani E, Mascolo N, Perretti M, D Acquisto F. IL-17A increases ADP-induced platelet aggregation. Biochem Biophys Res Commun. 2011;408:658-62 pubmed publisher
Puel A, Cypowyj S, Bustamante J, Wright J, Liu L, Lim H, et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science. 2011;332:65-8 pubmed publisher
Gaffen S. Structure and signalling in the IL-17 receptor family. Nat Rev Immunol. 2009;9:556-67 pubmed publisher
Toy D, Kugler D, Wolfson M, Vanden Bos T, Gurgel J, Derry J, et al. Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J Immunol. 2006;177:36-9 pubmed
Zhang Z, Zheng M, Bindas J, Schwarzenberger P, Kolls J. Critical role of IL-17 receptor signaling in acute TNBS-induced colitis. Inflamm Bowel Dis. 2006;12:382-8 pubmed
Tan W, Huang W, Zhong Q, Schwarzenberger P. IL-17 receptor knockout mice have enhanced myelotoxicity and impaired hemopoietic recovery following gamma irradiation. J Immunol. 2006;176:6186-93 pubmed

product information

Product Type :

Antibody

Product Name :

CD217 (IL-17Ra) Monoclonal Antibody (J10MBS), PE, eBioscience

Catalog # :

12-7517-42

Quantity :

100 Tests

Price :

US 397.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Human

Clone :

J10MBS

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

AW538159; CANDF5; CD127; CD217; CDw217; hIL-17R; IL-17 receptor A; IL17R; Il17ra; IL-17RA; interleukin 17 receptor A; interleukin-17 receptor A; MGC10262; VDw217