CX3CR1 Monoclonal Antibody (2A9-1), PE, eBioscience | Invitrogen 12-6099-41 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CX3CR1 Monoclonal Antibody (2A9-1), PE, eBioscience

catalog :

12-6099-41

quantity :

25 Tests

price :

US 159.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

2A9-1

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Wilson E, Singh A, Hullsiek K, Gibson D, Henry W, Lichtenstein K, et al. Monocyte-activation phenotypes are associated with biomarkers of inflammation and coagulation in chronic HIV infection. J Infect Dis. 2014;210:1396-406 pubmed publisher
	Vishnyakova P, Kuznetsova M, Poltavets A, Fomina M, Kiseleva V, Muminova K, et al. Distinct gene expression patterns for CD14++ and CD16++ monocytes in preeclampsia. Sci Rep. 2022;12:15469 pubmed publisher
	Ormel P, Vieira de Sá R, van Bodegraven E, Karst H, Harschnitz O, Sneeboer M, et al. Microglia innately develop within cerebral organoids. Nat Commun. 2018;9:4167 pubmed publisher
	Berry M, Mathews R, Ferdinand J, Jing C, Loudon K, Wlodek E, et al. Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone. Cell. 2017;170:860-874.e19 pubmed publisher
	Amos P, Fung S, Case A, Kifelew J, Osnis L, Smith C, et al. Modulation of Hematopoietic Lineage Specification Impacts TREM2 Expression in Microglia-Like Cells Derived From Human Stem Cells. ASN Neuro. 2017;9:1759091417716610 pubmed publisher
	Oh I, Suh D, Park S, Ha K. Fractalkine receptor chemokine (CX3CR1) influences on cervical and lumbar disc herniation. Indian J Orthop. 2015;49:239-44 pubmed publisher
	Baker J, Hullsiek K, Singh A, Wilson E, Henry K, Lichtenstein K, et al. Immunologic predictors of coronary artery calcium progression in a contemporary HIV cohort. AIDS. 2014;28:831-40 pubmed publisher
	Brunner P, Koszik F, Reininger B, Kalb M, Bauer W, Stingl G. Infliximab induces downregulation of the IL-12/IL-23 axis in 6-sulfo-LacNac (slan)+ dendritic cells and macrophages. J Allergy Clin Immunol. 2013;132:1184-1193.e8 pubmed publisher
	Cany J, van der Waart A, Tordoir M, Franssen G, Hangalapura B, De Vries J, et al. Natural killer cells generated from cord blood hematopoietic progenitor cells efficiently target bone marrow-residing human leukemia cells in NOD/SCID/IL2Rg(null) mice. PLoS ONE. 2013;8:e64384 pubmed publisher
	Allan D, Rybalov B, Awong G, Zuniga Pflucker J, Kopcow H, Carlyle J, et al. TGF-? affects development and differentiation of human natural killer cell subsets. Eur J Immunol. 2010;40:2289-95 pubmed publisher
	Vermijlen D, Brouwer M, Donner C, Liesnard C, Tackoen M, Van Rysselberge M, et al. Human cytomegalovirus elicits fetal gammadelta T cell responses in utero. J Exp Med. 2010;207:807-21 pubmed publisher
	Arques J, Hautefort I, Ivory K, Bertelli E, Regoli M, Clare S, et al. Salmonella induces flagellin- and MyD88-dependent migration of bacteria-capturing dendritic cells into the gut lumen. Gastroenterology. 2009;137:579-87, 587.e1-2 pubmed publisher
	Nishimura M, Umehara H, Nakayama T, Yoneda O, Hieshima K, Kakizaki M, et al. Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression. J Immunol. 2002;168:6173-80 pubmed

product information

Product Type :

Antibody

Product Name :

CX3CR1 Monoclonal Antibody (2A9-1), PE, eBioscience

Catalog # :

12-6099-41

Quantity :

25 Tests

Price :

US 159.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.125 ug)/test

Species :

Human

Clone :

2A9-1

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.125 ug)/test

Aliases :

Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28

more info or order :

Invitrogen product webpage