CD275 (B7-H2) Monoclonal Antibody (HK5.3), PE, eBioscience™ | Invitrogen 12-5985-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD275 (B7-H2) Monoclonal Antibody (HK5.3), PE, eBioscience™

catalog :

12-5985-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

HK5.3

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; loading ...; fig 1i	Zamarin D, Holmgaard R, Ricca J, Plitt T, Palese P, Sharma P, et al. Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity. Nat Commun. 2017;8:14340 pubmed publisher
flow cytometry; mouse; fig 2	Pizzolla A, Oh D, Luong S, Prickett S, Henstridge D, Febbraio M, et al. High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance. PLoS ONE. 2016;11:e0160407 pubmed publisher
flow cytometry; mouse; fig 5	Charles E, Joshi S, Ash J, Fox B, Farris A, Bzik D, et al. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect Immun. 2010;78:3484-92 pubmed publisher
flow cytometry; mouse; fig 5b	Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology. 2008;213:399-408 pubmed publisher
flow cytometry; mouse	Smith P, Walsh C, Mangan N, Fallon R, Sayers J, McKenzie A, et al. Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol. 2004;173:1240-8 pubmed
	Oseledchyk A, Ricca J, Gigoux M, Ko B, Redelman Sidi G, Walther T, et al. Lysis-independent potentiation of immune checkpoint blockade by oncolytic virus. Oncotarget. 2018;9:28702-28716 pubmed publisher
	Zamarin D, Ricca J, Sadekova S, Oseledchyk A, Yu Y, Blumenschein W, et al. PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy. J Clin Invest. 2018;128:1413-1428 pubmed publisher
	Schwartz C, Khan A, Floudas A, Saunders S, Hams E, Rodewald H, et al. ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control. J Exp Med. 2017;214:2507-2521 pubmed publisher
	Li Y, Liu X, Duan W, Tian H, Zhu G, He H, et al. Batf3-dependent CD8?+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages. EBioMedicine. 2017;18:188-198 pubmed publisher
	Tsuji R, Koizumi H, Aoki D, Watanabe Y, Sugihara Y, Matsushita Y, et al. Lignin-rich enzyme lignin (LREL), a cellulase-treated lignin-carbohydrate derived from plants, activates myeloid dendritic cells via Toll-like receptor 4 (TLR4). J Biol Chem. 2015;290:4410-21 pubmed publisher
	Lina T, Pinchuk I, House J, Yamaoka Y, Graham D, Beswick E, et al. CagA-dependent downregulation of B7-H2 expression on gastric mucosa and inhibition of Th17 responses during Helicobacter pylori infection. J Immunol. 2013;191:3838-46 pubmed publisher
	Mesnil C, Sabatel C, Marichal T, Toussaint M, Cataldo D, Drion P, et al. Resident CD11b(+)Ly6C(-) lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. PLoS ONE. 2012;7:e53242 pubmed publisher
	Jiang G, Sun D, Kaplan H, Shao H. Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells. PLoS ONE. 2012;7:e40510 pubmed publisher
	Heib V, Sparber F, Tripp C, Ortner D, Stoitzner P, Heufler C. Cytip regulates dendritic-cell function in contact hypersensitivity. Eur J Immunol. 2012;42:589-97 pubmed publisher
	Lombardi V, Speak A, Kerzerho J, Szely N, Akbari O. CD8???? and CD8???? plasmacytoid dendritic cells induce Foxp3? regulatory T cells and prevent the induction of airway hyper-reactivity. Mucosal Immunol. 2012;5:432-43 pubmed publisher
	Wythe S, Dodd J, Openshaw P, Schwarze J. OX40 ligand and programmed cell death 1 ligand 2 expression on inflammatory dendritic cells regulates CD4 T cell cytokine production in the lung during viral disease. J Immunol. 2012;188:1647-55 pubmed publisher
	Tomihara K, Guo M, Shin T, Sun X, Ludwig S, Brumlik M, et al. Antigen-specific immunity and cross-priming by epithelial ovarian carcinoma-induced CD11b(+)Gr-1(+) cells. J Immunol. 2010;184:6151-60 pubmed publisher
	Mitsui S, Torii K, Fukui H, Tsujimura K, Maeda A, Nose M, et al. The herbal medicine compound falcarindiol from Notopterygii Rhizoma suppresses dendritic cell maturation. J Pharmacol Exp Ther. 2010;333:954-60 pubmed publisher
	Zietara N, Łyszkiewicz M, Gekara N, Puchałka J, dos Santos V, Hunt C, et al. Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70. J Immunol. 2009;183:1099-109 pubmed publisher
	Chapoval S, Lee C, Tang C, Keegan A, Cohn L, Bottomly K, et al. Lung vascular endothelial growth factor expression induces local myeloid dendritic cell activation. Clin Immunol. 2009;132:371-84 pubmed publisher
	Colvin B, Sumpter T, Tokita D, Salati J, Mellor A, Thomson A. Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. Hum Immunol. 2009;70:313-20 pubmed publisher
	Stoitzner P, Tripp C, Douillard P, Saeland S, Romani N. Migratory Langerhans cells in mouse lymph nodes in steady state and inflammation. J Invest Dermatol. 2005;125:116-25 pubmed

product information

Product Type :

Antibody

Product Name :

CD275 (B7-H2) Monoclonal Antibody (HK5.3), PE, eBioscience™

Catalog # :

12-5985-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

HK5.3

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

AU044799; B7 homolog 2; B7 homologue 2; B7h; B7H2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP1; B7RP-1; BG071784; CD275; GI50; GL50; GL50-B; ICOS ligand; ICOSL; ICOS-L; ICOSLG; inducible T-cell costimulator ligand; inducible T-cell co-stimulator ligand; KIAA0653; LICOS; Ly115l; mKIAA0653; RGD1562791; transmembrane protein B7-H2 ICOS ligand

more info or order :

Invitrogen product webpage