E4BP4 (NFIL3) Monoclonal Antibody (S2M-E19), PE, eBioscience™ | Invitrogen 12-5927-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

E4BP4 (NFIL3) Monoclonal Antibody (S2M-E19), PE, eBioscience™

catalog :

12-5927-82

quantity :

100 µg

price :

US 394

clonality :

monoclonal

host :

rat

conjugate :

clone name :

S2M-E19

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200	Burton B, Britton G, Fang H, Verhagen J, Smithers B, Sabatos Peyton C, et al. Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy. Nat Commun. 2014;5:4741 pubmed publisher
	Wang Z, Zhao M, Yin J, Liu L, Hu L, Huang Y, et al. E4BP4-mediated inhibition of T follicular helper cell differentiation is compromised in autoimmune diseases. J Clin Invest. 2020;130:3717-3733 pubmed publisher
	Kashiwada M, Pham N, Pewe L, Harty J, Rothman P. NFIL3/E4BP4 is a key transcription factor for CD8α⁺ dendritic cell development. Blood. 2011;117:6193-7 pubmed publisher
	Gascoyne D, Long E, Veiga Fernandes H, de Boer J, Williams O, Seddon B, et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol. 2009;10:1118-24 pubmed publisher
	Cowell I. E4BP4/NFIL3, a PAR-related bZIP factor with many roles. Bioessays. 2002;24:1023-9 pubmed
	Ikushima S, Inukai T, Inaba T, Nimer S, Cleveland J, Look A. Pivotal role for the NFIL3/E4BP4 transcription factor in interleukin 3-mediated survival of pro-B lymphocytes. Proc Natl Acad Sci U S A. 1997;94:2609-14 pubmed
	Zhang W, Zhang J, Kornuc M, Kwan K, Frank R, Nimer S. Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter. Mol Cell Biol. 1995;15:6055-63 pubmed

product information

Product Type :

Antibody

Product Name :

E4BP4 (NFIL3) Monoclonal Antibody (S2M-E19), PE, eBioscience™

Catalog # :

12-5927-82

Quantity :

100 µg

Price :

US 394

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

S2M-E19

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Expression of interleukin-3 (IL3; MIM 147740) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site (Zhang et al., 1995 [PubMed 7565758]).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

AV225605; E4 promoter binding-protein 4; E4 promoter-binding protein 4; E4BP4; Embryo implantation-related NFIL3/E4BP4-like transcription factor; IL3BP1; Interleukin-3 promoter transcriptional activator; interleukin-3-binding protein 1; NF IL3A; Nfil3; NFIL3A; NF-IL3A; nuclear factor interleukin 3 regulated protein; nuclear factor interleukin-3-regulated protein; nuclear factor, interleukin 3 regulated; nuclear factor, interleukin 3, regulated; OTTHUMP00000021633; transcriptional activator NF-IL3A

more info or order :

Invitrogen product webpage