Ly-49I Monoclonal Antibody (YLI-90), PE, eBioscience™ | Invitrogen 12-5895-81 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Ly-49I Monoclonal Antibody (YLI-90), PE, eBioscience™

catalog :

12-5895-81

quantity :

50µg

price :

US 118

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

YLI-90

reactivity :

mouse

application :

flow cytometry

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 6b	Bern M, Beckman D, Ebihara T, Taffner S, Poursine Laurent J, White J, et al. Immunoreceptor tyrosine-based inhibitory motif-dependent functions of an MHC class I-specific NK cell receptor. Proc Natl Acad Sci U S A. 2017;114:E8440-E8447 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig 3d	Ohs I, Van Den Broek M, Nussbaum K, MUNZ C, Arnold S, Quezada S, et al. Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun. 2016;7:13708 pubmed publisher
flow cytometry; mouse; fig s1	Wensveen F, JelenÄiÄ‡ V, ValentiÄ‡ S, Å estan M, Wensveen T, Theurich S, et al. NK cells link obesity-induced adipose stress to inflammation and insulin resistance. Nat Immunol. 2015;16:376-85 pubmed publisher
	Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
	Kieckbusch J, Gaynor L, Moffett A, Colucci F. MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling. Nat Commun. 2014;5:3359 pubmed publisher
	Lee G, Liou Y, Wang S, Ko K, Jiang S, Liao N. Different NK cell developmental events require different levels of IL-15 trans-presentation. J Immunol. 2011;187:1212-21 pubmed publisher
	Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam L, Chrzanowska Wodnicka M, et al. Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. J Exp Med. 2010;207:1923-38 pubmed publisher
	Jonsson A, Yang L, Kim S, Taffner S, Yokoyama W. Effects of MHC class I alleles on licensing of Ly49A+ NK cells. J Immunol. 2010;184:3424-32 pubmed publisher
	Brenner C, King S, Przewoznik M, Wolters I, Adam C, Bornkamm G, et al. Requirements for control of B-cell lymphoma by NK cells. Eur J Immunol. 2010;40:494-504 pubmed publisher
	Hoover R, Gullickson G, Kornbluth J. Impaired NK cytolytic activity and enhanced tumor growth in NK lytic-associated molecule-deficient mice. J Immunol. 2009;183:6913-21 pubmed publisher
	Castillo E, Stonier S, Frasca L, Schluns K. Dendritic cells support the in vivo development and maintenance of NK cells via IL-15 trans-presentation. J Immunol. 2009;183:4948-56 pubmed publisher
	Joncker N, Fernandez N, Treiner E, Vivier E, Raulet D. NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol. 2009;182:4572-80 pubmed publisher
	Guo H, Samarakoon A, Vanhaesebroeck B, Malarkannan S. The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med. 2008;205:2419-35 pubmed publisher
	Malarkannan S, Regunathan J, Chu H, Kutlesa S, Chen Y, Zeng H, et al. Bcl10 plays a divergent role in NK cell-mediated cytotoxicity and cytokine generation. J Immunol. 2007;179:3752-62 pubmed
	Lu L, Zavitz C, Chen B, Kianpour S, Wan Y, Stampfli M. Cigarette smoke impairs NK cell-dependent tumor immune surveillance. J Immunol. 2007;178:936-43 pubmed
	Taki S, Nakajima S, Ichikawa E, Saito T, Hida S. IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells. J Immunol. 2005;174:6005-12 pubmed
	Regunathan J, Chen Y, Wang D, Malarkannan S. NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Blood. 2005;105:233-40 pubmed

product information

Product Type :

Antibody

Product Name :

Ly-49I Monoclonal Antibody (YLI-90), PE, eBioscience™

Catalog # :

12-5895-81

Quantity :

50µg

Price :

US 118

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

YLI-90

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

Ly49I; Ly-49I receptor; Ly49I receptor