KLRG1 Monoclonal Antibody (2F1), PE, eBioscience™ | Invitrogen 12-5893-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KLRG1 Monoclonal Antibody (2F1), PE, eBioscience™

catalog :

12-5893-82

quantity :

100 µg

price :

US 309.00

clonality :

monoclonal

host :

Syrian golden hamster

conjugate :

clone name :

2F1

reactivity :

mouse

application :

flow cytometry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; loading ...; fig 1c flow cytometry; mouse; loading ...; fig 1a	Meinicke H, Bremser A, Brack M, Schrenk K, Pircher H, Izcue A. KLRG1 impairs regulatory T-cell competitive fitness in the gut. Immunology. 2017;152:65-73 pubmed publisher
	Pokrovskii M, Hall J, Ochayon D, Yi R, Chaimowitz N, Seelamneni H, et al. Characterization of Transcriptional Regulatory Networks that Promote and Restrict Identities and Functions of Intestinal Innate Lymphoid Cells. Immunity. 2019;51:185-197.e6 pubmed publisher
	Isvoranu G, Surcel M, Huică R, Munteanu A, Pirvu I, Ciotaru D, et al. Natural killer cell monitoring in cutaneous melanoma - new dynamic biomarker. Oncol Lett. 2019;17:4197-4206 pubmed publisher
	Knolle M, Chin S, Rana B, Englezakis A, Nakagawa R, Fallon P, et al. MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity. Front Immunol. 2018;9:2232 pubmed publisher
	Van Braeckel Budimir N, Varga S, Badovinac V, Harty J. Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity. Cell Rep. 2018;24:3374-3382.e3 pubmed publisher
	Wang S, Xia P, Chen Y, Qu Y, Xiong Z, Ye B, et al. Regulatory Innate Lymphoid Cells Control Innate Intestinal Inflammation. Cell. 2017;171:201-216.e18 pubmed publisher
	Huang R, Francois A, McGray A, Miliotto A, Odunsi K. Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer. Oncoimmunology. 2017;6:e1249561 pubmed publisher
	Menendez C, Jinkins J, Carr D. Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency. J Immunol. 2016;197:1262-75 pubmed publisher
	Dong H, Franklin N, Ritchea S, Yagita H, Glennie M, Bullock T. CD70 and IFN-1 selectively induce eomesodermin or T-bet and synergize to promote CD8+ T-cell responses. Eur J Immunol. 2015;45:3289-301 pubmed publisher
	Hu Z, Molloy M, Usherwood E. CD4(+) T-cell dependence of primary CD8(+) T-cell response against vaccinia virus depends upon route of infection and viral dose. Cell Mol Immunol. 2016;13:82-93 pubmed publisher
	Ebert S, Becker M, Lemmermann N, Büttner J, Michel A, Taube C, et al. Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs. PLoS Pathog. 2014;10:e1004100 pubmed publisher
	Kieckbusch J, Gaynor L, Moffett A, Colucci F. MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling. Nat Commun. 2014;5:3359 pubmed publisher
	Fogel L, Sun M, Geurs T, Carayannopoulos L, French A. Markers of nonselective and specific NK cell activation. J Immunol. 2013;190:6269-76 pubmed publisher
	Cyktor J, Carruthers B, Stromberg P, Flano E, Pircher H, Turner J. Killer cell lectin-like receptor G1 deficiency significantly enhances survival after Mycobacterium tuberculosis infection. Infect Immun. 2013;81:1090-9 pubmed publisher
	Seckert C, Schader S, Ebert S, Thomas D, Freitag K, Renzaho A, et al. Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency. J Gen Virol. 2011;92:1994-2005 pubmed publisher

product information

Product Type :

Antibody

Product Name :

KLRG1 Monoclonal Antibody (2F1), PE, eBioscience™

Catalog # :

12-5893-82

Quantity :

100 µg

Price :

US 309.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Syrian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

2F1

Isotype :

IgG

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

2F1; 2F1-Ag; CLEC15A; C-type lectin domain family 15 member A; C-type lectin domain family 15, member A; ITIM-containing receptor MAFA-L; killer cell lectin like receptor G1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G, member 1; Klrg1; Mafa; MAFA-2F1; MAFAL; MAFA-L; MAFA-LIKE; MAFA-like receptor; Mast cell function-associated antigen; mast cell function-associated antigen (ITIM-containing); mast cell function-associated antigen 2F1; natural killer cell receptor

more info or order :

Invitrogen product webpage