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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Integrin beta 7 Monoclonal Antibody (FIB504), PE, eBioscience
catalog :
12-5867-42
quantity :
100 Tests
price :
US 300.00
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
FIB504
reactivity :
pigtail macaque, sooty mangabey, human, mouse, rhesus macaque
application :
flow cytometry
more info or order :
Invitrogen product webpage
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; rhesus macaque; fig 2c4
  • flow cytometry; sooty mangabey; fig 2c4
  • flow cytometry; pigtail macaque; loading ...; fig 2c4
Byrareddy S, Sidell N, Arthos J, Cicala C, Zhao C, Little D, et al. Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates. J Immunol. 2015;194:5968-79 pubmed publisher
Alhaj Hussen K, Chabaane E, Nelson E, Lekiashvili S, Diop S, Keita S, et al. Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation. iScience. 2023;26:107890 pubmed publisher
Achour A, Baychelier F, Besson C, Arnoux A, Marty M, Hannoun L, et al. Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients. J Immunol. 2014;192:503-11 pubmed publisher
Chenery A, Burrows K, Antignano F, Underhill T, Petkovich M, Zaph C. The retinoic acid-metabolizing enzyme Cyp26b1 regulates CD4 T cell differentiation and function. PLoS ONE. 2013;8:e72308 pubmed publisher
Alvarez Y, Tuen M, Shen G, Nawaz F, Arthos J, Wolff M, et al. Preferential HIV infection of CCR6+ Th17 cells is associated with higher levels of virus receptor expression and lack of CCR5 ligands. J Virol. 2013;87:10843-54 pubmed publisher
Pallikkuth S, Micci L, Ende Z, Iriele R, Cervasi B, Lawson B, et al. Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21. PLoS Pathog. 2013;9:e1003471 pubmed publisher
Chu C, Celik E, Rico F, Moy V. Elongated membrane tethers, individually anchored by high affinity ?4?1/VCAM-1 complexes, are the quantal units of monocyte arrests. PLoS ONE. 2013;8:e64187 pubmed publisher
Smith M, Bastidas S, Karrer U, Oxenius A. Impact of antigen specificity on CD4+ T cell activation in chronic HIV-1 infection. BMC Infect Dis. 2013;13:100 pubmed publisher
Moos V, Feurle G, Schinnerling K, Geelhaar A, Friebel J, Allers K, et al. Immunopathology of immune reconstitution inflammatory syndrome in Whipple's disease. J Immunol. 2013;190:2354-61 pubmed publisher
Scotta C, Esposito M, Fazekasova H, Fanelli G, Edozie F, Ali N, et al. Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4(+)CD25(+)FOXP3(+) T regulatory cell subpopulations. Haematologica. 2013;98:1291-9 pubmed publisher
Dahlin J, Feinstein R, Cui Y, Heyman B, Hallgren J. CD11c+ cells are required for antigen-induced increase of mast cells in the lung. J Immunol. 2012;189:3869-77 pubmed publisher
Wacleche V, Chomont N, Gosselin A, Monteiro P, Goupil M, Kared H, et al. The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin ?7 but not CCR6 and regulated by retinoic acid. PLoS ONE. 2012;7:e32964 pubmed publisher
Betts G, Jones E, Junaid S, El Shanawany T, Scurr M, Mizen P, et al. Suppression of tumour-specific CD4? T cells by regulatory T cells is associated with progression of human colorectal cancer. Gut. 2012;61:1163-71 pubmed publisher
Ciccone E, Greenwald J, Lee P, Biancotto A, Read S, Yao M, et al. CD4+ T cells, including Th17 and cycling subsets, are intact in the gut mucosa of HIV-1-infected long-term nonprogressors. J Virol. 2011;85:5880-8 pubmed publisher
Monteiro P, Gosselin A, Wacleche V, El Far M, Said E, Kared H, et al. Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin ?7. J Immunol. 2011;186:4618-30 pubmed publisher
Hovhannisyan Z, Treatman J, Littman D, Mayer L. Characterization of interleukin-17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology. 2011;140:957-65 pubmed publisher
Kapp K, Maul J, Hostmann A, Mundt P, Preiss J, Wenzel A, et al. Modulation of systemic antigen-specific immune responses by oral antigen in humans. Eur J Immunol. 2010;40:3128-37 pubmed publisher
Gosselin A, Monteiro P, Chomont N, Diaz Griffero F, Said E, Fonseca S, et al. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection. J Immunol. 2010;184:1604-16 pubmed publisher
Grindebacke H, Stenstad H, Quiding Jarbrink M, Waldenström J, Adlerberth I, Wold A, et al. Dynamic development of homing receptor expression and memory cell differentiation of infant CD4+CD25high regulatory T cells. J Immunol. 2009;183:4360-70 pubmed publisher
Soler D, Chapman T, Yang L, Wyant T, Egan R, Fedyk E. The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases. J Pharmacol Exp Ther. 2009;330:864-75 pubmed publisher
Lages C, Suffia I, Velilla P, Huang B, Warshaw G, Hildeman D, et al. Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol. 2008;181:1835-48 pubmed
Ali Z, Shao L, Halliday L, Reichenberg A, Hintz M, Jomaa H, et al. Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaques. J Immunol. 2007;179:8287-96 pubmed
McMillan B, McMillan S, Glover E, Bradfield C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin induces premature activation of the KLF2 regulon during thymocyte development. J Biol Chem. 2007;282:12590-7 pubmed
Hartigan O Connor D, Poon C, Sinclair E, McCune J. Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells. J Immunol Methods. 2007;319:41-52 pubmed publisher
Hirrlinger P, Scheller A, Braun C, Hirrlinger J, Kirchhoff F. Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2. Glia. 2006;54:11-20 pubmed
Koenen H, Fasse E, Joosten I. CD27/CFSE-based ex vivo selection of highly suppressive alloantigen-specific human regulatory T cells. J Immunol. 2005;174:7573-83 pubmed
Rodriguez M, Paquet A, Yang Y, Erle D. Differential gene expression by integrin beta 7+ and beta 7- memory T helper cells. BMC Immunol. 2004;5:13 pubmed
Meerschaert J, Vrtis R, Shikama Y, Sedgwick J, Busse W, Mosher D. Engagement of alpha4beta7 integrins by monoclonal antibodies or ligands enhances survival of human eosinophils in vitro. J Immunol. 1999;163:6217-27 pubmed
Andrew D, Berlin C, Honda S, Yoshino T, Hamann A, Holzmann B, et al. Distinct but overlapping epitopes are involved in alpha 4 beta 7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation. J Immunol. 1994;153:3847-61 pubmed
product information
Product Type :
Antibody
Product Name :
Integrin beta 7 Monoclonal Antibody (FIB504), PE, eBioscience
Catalog # :
12-5867-42
Quantity :
100 Tests
Price :
US 300.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 5 uL (0.125 ug)/test
Species :
Human, Mouse
Clone :
FIB504
Isotype :
IgG2a, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.125 ug)/test
Aliases :
Gut homing receptor beta subunit; integrin beta 7; integrin beta 7 subunit; integrin beta-7; Integrin beta-P; integrin subunit beta 7; integrin, beta 7; ITGB7; Ly69; M290 IEL antigen
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA