TdT Monoclonal Antibody (19-3), PE, eBioscience | Invitrogen 12-5846-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TdT Monoclonal Antibody (19-3), PE, eBioscience

catalog :

12-5846-82

quantity :

100 ug

price :

US 397.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

19-3

reactivity :

human, mouse

application :

flow cytometry

citations: 7

Reference
Lehrke M, Shapiro M, Rajcula M, Kennedy M, McCue S, Medina K, et al. The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice. elife. 2021;10: pubmed publisher
Nguyen T, Pawlikowska P, Firlej V, Rosselli F, Aoufouchi S. V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca-/- mice. Sci Rep. 2016;6:36906 pubmed publisher
Newrzela S, Al Ghaili N, Heinrich T, Petkova M, Hartmann S, Rengstl B, et al. T-cell receptor diversity prevents T-cell lymphoma development. Leukemia. 2012;26:2499-507 pubmed publisher
Gärtner D, Hoff H, Gimsa U, Burmester G, Brunner Weinzierl M. CD25 regulatory T cells determine secondary but not primary remission in EAE: impact on long-term disease progression. J Neuroimmunol. 2006;172:73-84 pubmed
Bollum F, Chang L. Immunological detection of a conserved structure for terminal deoxynucleotidyltransferase. J Biol Chem. 1981;256:8767-70 pubmed
Bardales R, Carrato A, Fleischer M, Schwartz M, Koziner B. Detection of terminal deoxynucleotidyl transferase (TdT) by flow cytometry in leukemic disorders. J Histochem Cytochem. 1989;37:509-13 pubmed
Bogue M, Gilfillan S, Benoist C, Mathis D. Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny. Proc Natl Acad Sci U S A. 1992;89:11011-5 pubmed

product information

Product Type :

Antibody

Product Name :

TdT Monoclonal Antibody (19-3), PE, eBioscience

Catalog # :

12-5846-82

Quantity :

100 ug

Price :

US 397.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 0.5 ug/test

Species :

Human, Mouse

Clone :

19-3

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leuksemias. The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt's lymphoma.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 ug/test

Aliases :

Deoxynucleotidyltransferase terminal; deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; Dntt; Nucleosidetriphosphate DNA Deoxynucleotidylexotransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; TDT; Terminal addition enzyme; terminal deoxynucleotidyl transferase; terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; terminal transferase