TSLP Receptor Monoclonal Antibody (eBio1A6 (1A6)), PE, eBioscience | Invitrogen 12-5499-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TSLP Receptor Monoclonal Antibody (eBio1A6 (1A6)), PE, eBioscience

catalog :

12-5499-42

quantity :

100 Tests

price :

US 388.00

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

eBio1A6 (1A6)

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig s5c	Kim S, Knight D, Jones L, Vervoort S, Ng A, Seymour J, et al. JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias. Genes Dev. 2018;32:849-864 pubmed publisher
	Wu S, Li L, Kopp N, Montero J, Chapuy B, Yoda A, et al. Activity of the Type II JAK2 Inhibitor CHZ868 in B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2015;28:29-41 pubmed publisher
	Miazgowicz M, Elliott M, Debley J, Ziegler S. Respiratory syncytial virus induces functional thymic stromal lymphopoietin receptor in airway epithelial cells. J Inflamm Res. 2013;6:53-61 pubmed publisher
	Ott C, Kopp N, Bird L, Paranal R, Qi J, Bowman T, et al. BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia. Blood. 2012;120:2843-52 pubmed publisher
	Chapiro E, Russell L, Lainey E, Kaltenbach S, Ragu C, Della Valle V, et al. Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia. 2010;24:642-5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TSLP Receptor Monoclonal Antibody (eBio1A6 (1A6)), PE, eBioscience

Catalog # :

12-5499-42

Quantity :

100 Tests

Price :

US 388.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL (0.06 ug)/test

Species :

Human

Clone :

eBio1A6 (1A6)

Isotype :

IgG2a, lambda

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells; co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.06 ug)/test

Aliases :

CRL2; Crlf2; CRLF2Y; Crlm2; CRLM-2; cytokine receptor CRL2 precusor; Cytokine receptor-like 2; Cytokine receptor-like factor 2; cytokine receptor-like molecule 2; delta 1; ILXR; IL-XR; Ly114; lymphocyte antigen 114; P2RY8/CRLF2 fusion; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin receptor; thymic stromal-derived lymphopoietin, receptor; Tpte2; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; TSLP receptor; Tslpr; type I cytokine receptor delta 1; WI2-87105E3.1

more info or order :

Invitrogen product webpage