CD5 Monoclonal Antibody (YKIX322.3), PE, eBioscience | Invitrogen 12-5050-41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD5 Monoclonal Antibody (YKIX322.3), PE, eBioscience

catalog :

12-5050-41

quantity :

25 Tests

price :

US 133.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

YKIX322.3

The same clone is also sold as:

Bio-Rad: MCA1037F, MCA1037GA

reactivity :

dogs

application :

flow cytometry

citations: 8

Reference
Rotolo A, Atherton M, Kasper B, Haran K, Mason N. Genetic re-direction of canine primary T cells for clinical trial use in pet dogs with spontaneous cancer. STAR Protoc. 2021;2:100905 pubmed publisher
Gingrich A, Reiter T, Judge S, York D, Yanagisawa M, Razmara A, et al. Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target. Front Immunol. 2021;12:670309 pubmed publisher
Panjwani M, Atherton M, Maloneyhuss M, Haran K, Xiong A, Gupta M, et al. Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma. Oncoimmunology. 2020;9:1676615 pubmed publisher
Panjwani M, Smith J, Schutsky K, Gnanandarajah J, O Connor C, Powell D, et al. Feasibility and Safety of RNA-transfected CD20-specific Chimeric Antigen Receptor T Cells in Dogs with Spontaneous B Cell Lymphoma. Mol Ther. 2016;24:1602-14 pubmed publisher
Mustafa A, Holladay S, Witonsky S, Sponenberg D, Karpuzoglu E, Gogal R. A single mid-gestation exposure to TCDD yields a postnatal autoimmune signature, differing by sex, in early geriatric C57BL/6 mice. Toxicology. 2011;290:156-68 pubmed publisher
Huang Y, Hung S, Jan T, Liao K, Cheng C, Wang Y, et al. CD5-low expression lymphocytes in canine peripheral blood show characteristics of natural killer cells. J Leukoc Biol. 2008;84:1501-10 pubmed publisher
Rabanal R, Ferrer L, Else R. Immunohistochemical detection of canine leucocyte antigens by specific monoclonal antibodies in canine normal tissues. Vet Immunol Immunopathol. 1995;47:13-23 pubmed
Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994;43:137-54 pubmed

product information

Product Type :

Antibody

Product Name :

CD5 Monoclonal Antibody (YKIX322.3), PE, eBioscience

Catalog # :

12-5050-41

Quantity :

25 Tests

Price :

US 133.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Canine

Applications :

Flow Cytometry: 5 uL (0.25 ug)/test

Species :

Canine

Clone :

YKIX322.3

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL (0.25 ug)/test

Aliases :

alanyl (membrane) aminopeptidase; alanyl aminopeptidase; alanyl aminopeptidase, membrane; aminopeptidase M; Aminopeptidase N; ANPEP; AP-M; APN; AP-N; CD antigen CD5; CD13; CD28; CD28 antigen (Tp44); CD28 molecule; Cd5; CD5 antigen; CD5 antigen (p56 62); CD5 antigen (p56-62); CD5 antigen p56-62; CD5 molecule; CD5 protein; CD74 antigen, invariant polypeptide of major; cell surface protein; costimulatory molecule B7 receptor CD28; fCD5; GP150; hAPN; LAP1; LEU1; Ly-1; Ly12; Ly-12; LyA; Ly-A; Lymphocyte antigen 1; Lymphocyte antigen CD5; lymphocyte antigen T1/Leu-1; Lyt-1; membrane alanyl aminopeptidase; microsomal aminopeptidase; Myeloid plasma membrane glycoprotein CD13; P150; Pan T cell; PEPN; T1; T-cell costimulatory molecule CD28; T-cell surface glycoprotein CD5; T-cell-specific surface glycoprotein CD28; unnamed protein product