CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio927), PE, eBioscience | Invitrogen 12-3172-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio927), PE, eBioscience

catalog :

12-3172-81

quantity :

50 µg

price :

US 209

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBio927

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 31

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 3	Charles E, Joshi S, Ash J, Fox B, Farris A, Bzik D, et al. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect Immun. 2010;78:3484-92 pubmed publisher
	Kraemer A, Sch xe4 fer A, Sprenger D, Sehnert B, Williams J, Luo A, et al. Impact of dietary vitamin D on immunoregulation and disease pathology in lupus-prone NZB/W F1 mice. Front Immunol. 2022;13:933191 pubmed publisher
	Lutz M, Ali S, Audiger C, Autenrieth S, Berod L, Bigley V, et al. Guidelines for mouse and human DC generation. Eur J Immunol. 2022;: pubmed publisher
	Balzano M, De Grandis M, Vu Manh T, Chasson L, Bardin F, Farina A, et al. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Rep. 2019;26:3257-3271.e8 pubmed publisher
	Lu X, Ding Z, Cao Y, Liu C, Habtetsion T, Yu M, et al. Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells. J Immunol. 2015;194:2011-21 pubmed publisher
	Busch M, Westhofen T, Koch M, Lutz M, Zernecke A. Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice. PLoS ONE. 2014;9:e88452 pubmed publisher
	Kobayashi Y, Iwata A, Suzuki K, Suto A, Kawashima S, Saito Y, et al. B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells. Proc Natl Acad Sci U S A. 2013;110:5121-6 pubmed publisher
	Park S, Jing X, Gupta D, Dziarski R. Peptidoglycan recognition protein 1 enhances experimental asthma by promoting Th2 and Th17 and limiting regulatory T cell and plasmacytoid dendritic cell responses. J Immunol. 2013;190:3480-92 pubmed publisher
	Dong H, Stanek O, Salvador F, Langer U, Morillon E, Ung C, et al. Induction of protective immunity against Mycobacterium tuberculosis by delivery of ESX antigens into airway dendritic cells. Mucosal Immunol. 2013;6:522-34 pubmed publisher
	Mohammed J, Gunderson A, Khong H, Koubek R, Udey M, Glick A. TGF?1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity. J Invest Dermatol. 2013;133:135-43 pubmed publisher
	Bachem A, Hartung E, Güttler S, Mora A, Zhou X, Hegemann A, et al. Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation. Front Immunol. 2012;3:214 pubmed publisher
	Mizuno S, Kanai T, Mikami Y, Sujino T, Ono Y, Hayashi A, et al. CCR9+ plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice. Immunol Lett. 2012;146:64-9 pubmed publisher
	Ritprajak P, Hayakawa M, Sano Y, Otsu K, Park J. Cell type-specific targeting dissociates the therapeutic from the adverse effects of protein kinase inhibition in allergic skin disease. Proc Natl Acad Sci U S A. 2012;109:9089-94 pubmed publisher
	Noel G, DeKoter R, Wang Q, Hexley P, Ogle C. Optimization and application of a flow cytometric PU.1 assay for murine immune cells. J Immunol Methods. 2012;382:81-92 pubmed publisher
	Barrett B, Smith D, Li S, Guo K, Hasenkrug K, Santiago M. A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo. PLoS Pathog. 2012;8:e1002596 pubmed publisher
	Benson H, Suzuki H, Lott J, Fisher A, Walline C, Heidler K, et al. Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production. Respir Res. 2012;13:25 pubmed publisher
	Siggs O, Li X, Xia Y, Beutler B. ZBTB1 is a determinant of lymphoid development. J Exp Med. 2012;209:19-27 pubmed publisher
	Triozzi P, Aldrich W, Ponnazhagan S. Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists. Cancer Gene Ther. 2011;18:850-8 pubmed publisher
	Wainwright D, Balyasnikova I, Han Y, Lesniak M. The expression of BST2 in human and experimental mouse brain tumors. Exp Mol Pathol. 2011;91:440-6 pubmed publisher
	Ohue R, Nakamoto M, Kitabatake N, Tani F. Changes in lamina propria dendritic cells on the oral administration of exogenous protein antigens during weaning. Cytotechnology. 2012;64:221-30 pubmed publisher
	Guarda G, Zenger M, Yazdi A, Schroder K, Ferrero I, Menu P, et al. Differential expression of NLRP3 among hematopoietic cells. J Immunol. 2011;186:2529-34 pubmed publisher
	Shaw P, Barr M, Lukens J, McGargill M, Chi H, Mak T, et al. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity. 2011;34:75-84 pubmed publisher
	Cheung D, Ehlenbach S, Kitchens R, Riley D, Thomas L, Holtzman M, et al. Cutting edge: CD49d+ neutrophils induce FcepsilonRI expression on lung dendritic cells in a mouse model of postviral asthma. J Immunol. 2010;185:4983-7 pubmed publisher
	Freire T, Zhang X, Deriaud E, Ganneau C, Vichier Guerre S, Azria E, et al. Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant. Blood. 2010;116:3526-36 pubmed publisher
	Goffinet C, Schmidt S, Kern C, Oberbremer L, Keppler O. Endogenous CD317/Tetherin limits replication of HIV-1 and murine leukemia virus in rodent cells and is resistant to antagonists from primate viruses. J Virol. 2010;84:11374-84 pubmed publisher
	Mishima Y, Ishihara S, Aziz M, Oka A, Kusunoki R, Otani A, et al. Decreased production of interleukin-10 and transforming growth factor-? in Toll-like receptor-activated intestinal B cells in SAMP1/Yit mice. Immunology. 2010;131:473-87 pubmed publisher
	Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, et al. Foxa2 programs Th2 cell-mediated innate immunity in the developing lung. J Immunol. 2010;184:6133-41 pubmed publisher
	Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold C, et al. Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells. Proc Natl Acad Sci U S A. 2010;107:9759-64 pubmed publisher
	Bar On L, Jung S. Defining in vivo dendritic cell functions using CD11c-DTR transgenic mice. Methods Mol Biol. 2010;595:429-42 pubmed publisher
	Chung J, Yudate T, Tomihari M, Akiyoshi H, Cruz P, Ariizumi K. Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function. J Immunol. 2009;183:5190-8 pubmed publisher
	Blasius A, Giurisato E, Cella M, Schreiber R, Shaw A, Colonna M. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol. 2006;177:3260-5 pubmed

product information

Product Type :

Antibody

Product Name :

CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio927), PE, eBioscience

Catalog # :

12-3172-81

Quantity :

50 µg

Price :

US 209

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 µg/test

Species :

Mouse

Clone :

eBio927

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

BST2 (CD317, HM1.24 antigen, DAMP-2, tetherin) is an integral membrane protein that is involved in the development and growth of B-cells. The surface expression of BST2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line. BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, NK cells and DCs (at protein level), and myeloma cells. Research studies have shown that BST2 also functions as an inhibitor of retrovirus release from human cells whose activity is antagonized by the HIV-1 accessory protein, Vpu. While BST2 causes retention of virions on cell surfaces or endocytosis into BST2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release, an activity that may represent a potential therapeutic strategy for the treatment of HIV/AIDS. Another disease associated with BST2 dysfunction is stomatitis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 µg/test

Aliases :

2310015I10Rik; bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN

more info or order :

Invitrogen product webpage