CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio129c (129c)), PE, eBioscience | Invitrogen 12-3171-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio129c (129c)), PE, eBioscience

catalog :

12-3171-82

quantity :

100 µg

price :

US 402

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBio129c (129c)

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 20

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...	Piersma S, Poursine Laurent J, Yang L, Barber G, Parikh B, Yokoyama W. Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING. elife. 2020;9: pubmed publisher
flow cytometry; mouse; loading ...; fig 1d	Panda S, Facchinetti V, Voynova E, Hanabuchi S, Karnell J, Hanna R, et al. Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models. J Clin Invest. 2018;128:1873-1887 pubmed publisher
	Ciecko A, Foda B, Barr J, Ramanathan S, Atkinson M, Serreze D, et al. Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation. Cell Rep. 2019;29:3073-3086.e5 pubmed publisher
	Pelka K, Bertheloot D, Reimer E, Phulphagar K, Schmidt S, Christ A, et al. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport. Immunity. 2018;48:911-922.e7 pubmed publisher
	Bencherif S, Warren Sands R, Ali O, Li W, Lewin S, Braschler T, et al. Injectable cryogel-based whole-cell cancer vaccines. Nat Commun. 2015;6:7556 pubmed publisher
	Narusawa M, Inoue H, Sakamoto C, Matsumura Y, Takahashi A, Inoue T, et al. TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells. Cancer Immunol Res. 2014;2:568-80 pubmed publisher
	Agudo J, Ruzo A, Tung N, Salmon H, Leboeuf M, Hashimoto D, et al. The miR-126-VEGFR2 axis controls the innate response to pathogen-associated nucleic acids. Nat Immunol. 2014;15:54-62 pubmed publisher
	Liu H, Ramachandran I, Gabrilovich D. Regulation of plasmacytoid dendritic cell development in mice by aryl hydrocarbon receptor. Immunol Cell Biol. 2014;92:200-3 pubmed publisher
	Maina V, Marrella V, Mantero S, Cassani B, Fontana E, Anselmo A, et al. Hypomorphic mutation in the RAG2 gene affects dendritic cell distribution and migration. J Leukoc Biol. 2013;94:1221-30 pubmed publisher
	Svensson M, Andersson S, Erlandsson M, Jonsson I, Ekwall A, Andersson K, et al. Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis. PLoS ONE. 2013;8:e54884 pubmed publisher
	Chen Q, Snapper C. Inflammatory monocytes are critical for induction of a polysaccharide-specific antibody response to an intact bacterium. J Immunol. 2013;190:1048-55 pubmed publisher
	Vicetti Miguel R, Hendricks R, Aguirre A, Melan M, Harvey S, Terry Allison T, et al. Dendritic cell activation and memory cell development are impaired among mice administered medroxyprogesterone acetate prior to mucosal herpes simplex virus type 1 infection. J Immunol. 2012;189:3449-61 pubmed
	Majer O, Bourgeois C, Zwolanek F, Lassnig C, Kerjaschki D, Mack M, et al. Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections. PLoS Pathog. 2012;8:e1002811 pubmed publisher
	Day S, Ledford J, Zhou P, Lewkowich I, Page K. German cockroach proteases and protease-activated receptor-2 regulate chemokine production and dendritic cell recruitment. J Innate Immun. 2012;4:100-10 pubmed publisher
	Fujita J, Mizuki M, Otsuka M, Ezoe S, Tanaka H, Satoh Y, et al. Myeloid neoplasm-related gene abnormalities differentially affect dendritic cell differentiation from murine hematopoietic stem/progenitor cells. Immunol Lett. 2011;136:61-73 pubmed publisher
	Jang S, Schaller M, Berlin A, Lukacs N. Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity. J Immunol. 2010;185:5835-44 pubmed publisher
	Heng Y, Ma Y, Yin H, Duan L, Xiong P, Xu Y, et al. Adoptive transfer of FTY720-treated immature BMDCs significantly prolonged cardiac allograft survival. Transpl Int. 2010;23:1259-70 pubmed publisher
	Eppert B, Motz G, Wortham B, Flury J, Borchers M. CCR7 deficiency leads to leukocyte activation and increased clearance in response to pulmonary Pseudomonas aeruginosa infection. Infect Immun. 2010;78:2099-107 pubmed publisher
	Tirapu I, Giquel B, Alexopoulou L, Uematsu S, Flavell R, Akira S, et al. PolyI:C-induced reduction in uptake of soluble antigen is independent of dendritic cell activation. Int Immunol. 2009;21:871-9 pubmed publisher
	Blasius A, Giurisato E, Cella M, Schreiber R, Shaw A, Colonna M. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol. 2006;177:3260-5 pubmed

product information

Product Type :

Antibody

Product Name :

CD317 (BST2, PDCA-1) Monoclonal Antibody (eBio129c (129c)), PE, eBioscience

Catalog # :

12-3171-82

Quantity :

100 µg

Price :

US 402

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.5 µg/test

Species :

Mouse

Clone :

eBio129c (129c)

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

BST2 (CD317, HM1.24 antigen, DAMP-2, tetherin) is an integral membrane protein that is involved in the development and growth of B-cells. The surface expression of BST2 on fibroblast cell lines facilitated the stromal cell-dependent growth of DW34, a pre-B-cell line. BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, NK cells and DCs (at protein level), and myeloma cells. Research studies have shown that BST2 also functions as an inhibitor of retrovirus release from human cells whose activity is antagonized by the HIV-1 accessory protein, Vpu. While BST2 causes retention of virions on cell surfaces or endocytosis into BST2-positive compartments, its depletion abolished the viral requirement for Vpu for virus release, an activity that may represent a potential therapeutic strategy for the treatment of HIV/AIDS. Another disease associated with BST2 dysfunction is stomatitis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.5 µg/test

Aliases :

2310015I10Rik; bone marrow stromal antigen 2; bone marrow stromal cell antigen 2; Bst2; BST-2; C87040; CD317; Damp1; DAMP-1; DAMP-1 protein homolog; GREG; HM1.24 antigen; NPC-A-7; PDCA-1; protein DAMP-1; TETHERIN

more info or order :

Invitrogen product webpage