This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD290 (TLR10) Monoclonal Antibody (3C10C5), PE, eBioscience
catalog :
12-2909-42
quantity :
100 Tests
price :
US 416.00
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
3C10C5

The same clone is also sold as:
reactivity :
human
application :
flow cytometry
citations: 6
Reference
da Rocha Sobrinho H, Saar Gomes R, da Silva D, Quixabeira V, Joosten L, Ribeiro De Barros Cardoso C, et al. Toll-like receptor 10 controls TLR2-induced cytokine production in monocytes from patients with Parkinson's disease. J Neurosci Res. 2021;99:2511-2524 pubmed publisher
Sindhu S, Akhter N, Kochumon S, Thomas R, Wilson A, Shenouda S, et al. Increased Expression of the Innate Immune Receptor TLR10 in Obesity and Type-2 Diabetes: Association with ROS-Mediated Oxidative Stress. Cell Physiol Biochem. 2018;45:572-590 pubmed publisher
Govindaraj R, Manavalan B, Lee G, Choi S. Molecular modeling-based evaluation of hTLR10 and identification of potential ligands in Toll-like receptor signaling. PLoS ONE. 2010;5:e12713 pubmed publisher
Guan Y, Ranoa D, Jiang S, Mutha S, Li X, Baudry J, et al. Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling. J Immunol. 2010;184:5094-103 pubmed publisher
Bell M, Svingen P, Rahman M, Xiong Y, Faubion W. FOXP3 regulates TLR10 expression in human T regulatory cells. J Immunol. 2007;179:1893-900 pubmed
Hasan U, Chaffois C, Gaillard C, Saulnier V, Merck E, Tancredi S, et al. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol. 2005;174:2942-50 pubmed
product information
Product Type :
Antibody
Product Name :
CD290 (TLR10) Monoclonal Antibody (3C10C5), PE, eBioscience
Catalog # :
12-2909-42
Quantity :
100 Tests
Price :
US 416.00
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Mouse
Reactivity :
Human
Applications :
Flow Cytometry: 5 uL (0.25 ug)/test
Species :
Human
Clone :
3C10C5
Isotype :
IgG1, kappa
Storage :
4 C, store in dark, DO NOT FREEZE!
Description :
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Its exact function is not known. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 5 uL (0.25 ug)/test
Aliases :
CD290; MGC104967; MGC126398; MGC126399; TLR10; toll like receptor 10; toll-like receptor 10; UNQ315/PRO358
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA