CD244.2 (2B4) Monoclonal Antibody (eBio244F4), PE, eBioscience | Invitrogen 12-2441-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD244.2 (2B4) Monoclonal Antibody (eBio244F4), PE, eBioscience

catalog :

12-2441-82

quantity :

100 ug

price :

US 239.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBio244F4

reactivity :

mouse

application :

flow cytometry

citations: 9

Reference
Li Z, Morman R, Hegermiller E, Sun M, Bartom E, Maienschein Cline M, et al. The transcriptional repressor ID2 supports natural killer cell maturation by controlling TCF1 amplitude. J Exp Med. 2021;218: pubmed publisher
Hansel C, Erschfeld S, Baues M, Lammers T, Weiskirchen R, Trautwein C, et al. The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis. Front Pharmacol. 2019;10:244 pubmed publisher
Tang P, Zhou S, Meng X, Wang Q, Li C, Lian G, et al. Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development. Nat Commun. 2017;8:14677 pubmed publisher
Sinai P, Dozmorov I, Song R, Schwartzberg P, Wakeland E, WÃ¼lfing C. T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice. Eur J Immunol. 2014;44:3522-31 pubmed publisher
Trotta R, Chen L, Costinean S, Josyula S, Mundy Bosse B, Ciarlariello D, et al. Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells. Blood. 2013;121:3126-34 pubmed publisher
Wortham B, Eppert B, Motz G, Flury J, Orozco Levi M, Hoebe K, et al. NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. J Immunol. 2012;188:4468-75 pubmed publisher
Youn J, Collazo M, Shalova I, Biswas S, Gabrilovich D. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol. 2012;91:167-81 pubmed publisher
Hartner J, Walkley C, Lu J, Orkin S. ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat Immunol. 2009;10:109-15 pubmed publisher
Sugano Y, Takeuchi M, Hirata A, Matsushita H, Kitamura T, Tanaka M, et al. Junctional adhesion molecule-A, JAM-A, is a novel cell-surface marker for long-term repopulating hematopoietic stem cells. Blood. 2008;111:1167-72 pubmed

product information

Product Type :

Antibody

Product Name :

CD244.2 (2B4) Monoclonal Antibody (eBio244F4), PE, eBioscience

Catalog # :

12-2441-82

Quantity :

100 ug

Price :

US 239.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

eBio244F4

Isotype :

IgG2a

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

2B4; C9.1; Cd244; CD244 long isoform; CD244 natural killer cell receptor 2B4; CD244 short isoform; F730046O15Rik; Ly90; NAIL; natural killer cell receptor; natural killer cell receptor 2B4; NK cell receptor 2B4; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; non MHC restricted killing associated; non-MHC restricted killing associated; Signaling lymphocytic activation molecule 4; SLAM family member 4; SLAMF4