CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), PE, eBioscience | Invitrogen 12-2012-80 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), PE, eBioscience

catalog :

12-2012-80

quantity :

25 ug

price :

US 157.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBio1560 (1560)

reactivity :

mouse

application :

flow cytometry

citations: 20

Reference
Zhou Y, Ye Z, Wei W, Zhang M, Huang F, Li J, et al. Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis. NPJ Regen Med. 2023;8:23 pubmed publisher
Chavez J, Rabe J, Hernandez G, Mills T, Niño K, Davizon Castillo P, et al. PU.1 Expression Defines Distinct Functional Activities in the Phenotypic HSC Compartment of a Murine Inflammatory Stress Model. Cells. 2022;11: pubmed publisher
Wang R, Huang F, Wei W, Zhou Y, Ye Z, Yu L, et al. Programmed Cell Death Ligand 1 Is Enriched in Mammary Stem Cells and Promotes Mammary Development and Regeneration. Front Cell Dev Biol. 2021;9:772669 pubmed publisher
Avci S, Gur Cohen S, Avemaria F, Lapidot T. Adhesion Assay for Murine Bone Marrow Hematopoietic Stem Cells. Bio Protoc. 2017;7:e2135 pubmed publisher
Wu T, Wang Y, Xiao T, Ai Y, Li J, Zeng Y, et al. Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium. BMC Biotechnol. 2021;21:42 pubmed publisher
Wang D, Wang J, Bai L, Pan H, Feng H, Clevers H, et al. Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors. Cell. 2020;180:1198-1211.e19 pubmed publisher
Wang J, Wang D, Chu K, Li W, Zeng Y. Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium. Nat Commun. 2019;10:4966 pubmed publisher
Wang D, Hu X, Liu C, Jia Y, Bai Y, Cai C, et al. Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers. Cell Res. 2019;29:832-845 pubmed publisher
Mantri C, St John A. Immune synapses between mast cells and γδ T cells limit viral infection. J Clin Invest. 2019;129:1094-1108 pubmed publisher
Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher
Gur Cohen S, Itkin T, Chakrabarty S, Graf C, Kollet O, Ludin A, et al. PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat Med. 2015;21:1307-17 pubmed publisher
Lee C, Castle K, Moding E, Blum J, Williams N, Luo L, et al. Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma. Nat Commun. 2015;6:8477 pubmed publisher
Bunaciu R, Yen A. 6-Formylindolo (3,2-b)carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells. Mol Cancer. 2013;12:39 pubmed publisher
Friedman G, Raborn J, Kelly V, Cassady K, Markert J, Gillespie G. Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy. Front Oncol. 2013;3:28 pubmed publisher
Nishiura H, Zhao R, Yamamoto T. Dual functions of the C5a receptor as a connector for the K562 erythroblast-like cell-THP-1 macrophage-like cell island and as a sensor for the differentiation of the K562 erythroblast-like cell during haemin-induced erythropoiesis. Clin Dev Immunol. 2012;2012:187080 pubmed publisher
Zunino S, Storms D, Newman J, Pedersen T, Keen C, Ducore J. Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. Int J Oncol. 2013;42:741-8 pubmed publisher
Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, et al. Antigen aggregation decides the fate of the allergic immune response. J Immunol. 2010;184:725-35 pubmed publisher
Balazs A, Fabian A, Esmon C, Mulligan R. Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood. 2006;107:2317-21 pubmed
Li W, Zheng X, Gu J, Ferrell G, Brady M, Esmon N, et al. Extraembryonic expression of EPCR is essential for embryonic viability. Blood. 2005;106:2716-22 pubmed
Fukudome K, Esmon C. Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR. J Biol Chem. 1995;270:5571-7 pubmed

product information

Product Type :

Antibody

Product Name :

CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), PE, eBioscience

Catalog # :

12-2012-80

Quantity :

25 ug

Price :

US 157.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1 ug/test

Species :

Mouse

Clone :

eBio1560 (1560)

Isotype :

IgG2b, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1 ug/test

Aliases :

Activated protein C receptor; AI325044; APC receptor; bA42O4.2; CCCA; CCD41; CD antigen CD201; CD201; CD201 antigen; cell cycle, centrosome-associated protein; centrocyclin; Centrosomal protein CCD41; endothelial cell protein C receptor; Endothelial protein C receptor; Epcr; PROCR; protein C receptor; protein C receptor, endothelial