CD166 (ALCAM) Monoclonal Antibody (3A6), PE, eBioscience™ | Invitrogen 12-1668-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD166 (ALCAM) Monoclonal Antibody (3A6), PE, eBioscience™

catalog :

12-1668-42

quantity :

100 Tests

price :

US 341

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3A6

reactivity :

human, mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3d	Barros Silva J, Linn D, Steiner I, Guo G, Ali A, Pakula H, et al. Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Rep. 2018;25:3504-3518.e6 pubmed publisher
	Gong B, Zheng L, Lu Z, Huang J, Pu J, Pan S, et al. Mesenchymal stem cells negatively regulate CD4<sup>+</sup> T cell activation in patients with primary Sjögren syndrome through the miRNA‑125b and miRNA‑155 TCR pathway. Mol Med Rep. 2021;23: pubmed publisher
	Han B, Zhou L, Guan Q, da Roza G, Wang H, Du C. In Vitro Expansion and Characterization of Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent in a Human Protein Medium. Stem Cells Int. 2018;2018:5868745 pubmed publisher
	Ilmer M, Mazurek N, Byrd J, Ramirez K, Hafley M, Alt E, et al. Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics. Cell Death Dis. 2016;7:e2337 pubmed publisher
	Bauderlique Le Roy H, Vennin C, Brocqueville G, Spruyt N, Adriaenssens E, Bourette R. Enrichment of Human Stem-Like Prostate Cells with s-SHIP Promoter Activity Uncovers a Role in Stemness for the Long Noncoding RNA H19. Stem Cells Dev. 2015;24:1252-62 pubmed publisher
	Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed publisher
	King J, Tan F, Mbeunkui F, Chambers Z, Cantrell S, Chen H, et al. Mechanisms of transcriptional regulation and prognostic significance of activated leukocyte cell adhesion molecule in cancer. Mol Cancer. 2010;9:266 pubmed publisher
	Piazza T, Cha E, Bongarzone I, Canevari S, Bolognesi A, Polito L, et al. Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody. J Cell Sci. 2005;118:1515-25 pubmed
	Saifullah M, Fox D, Sarkar S, Abidi S, Endres J, Piktel J, et al. Expression and characterization of a novel CD6 ligand in cells derived from joint and epithelial tissues. J Immunol. 2004;173:6125-33 pubmed
	van Kempen L, Nelissen J, Degen W, Torensma R, Weidle U, Bloemers H, et al. Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCAM)-ALCAM interaction. J Biol Chem. 2001;276:25783-90 pubmed
	Bowen M, Patel D, Li X, Modrell B, Malacko A, Wang W, et al. Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J Exp Med. 1995;181:2213-20 pubmed

product information

Product Type :

Antibody

Product Name :

CD166 (ALCAM) Monoclonal Antibody (3A6), PE, eBioscience™

Catalog # :

12-1668-42

Quantity :

100 Tests

Price :

US 341

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.06 µg)/test

Species :

Human

Clone :

3A6

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.06 µg)/test

Aliases :

Activated leukocyte cell adhesion molecule; AI853494; Alcam; BEN; CD166; CD166 antigen; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product

more info or order :

Invitrogen product webpage