CD166 (ALCAM) Monoclonal Antibody (eBioALC48), PE, eBioscience | Invitrogen 12-1661-82 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD166 (ALCAM) Monoclonal Antibody (eBioALC48), PE, eBioscience

catalog :

12-1661-82

quantity :

100 ug

price :

US 265.00

clonality :

monoclonal

host :

rat

conjugate :

clone name :

eBioALC48

reactivity :

mouse

application :

flow cytometry

citations: 21

Reference
Gui Y, Qian X, Ding Y, Chen Q, Fangyu Ye -, Ye Y, et al. c-Fos regulated by TMPO/ERK axis promotes 5-FU resistance via inducing NANOG transcription in colon cancer. Cell Death Dis. 2024;15:61 pubmed publisher
Dushime H, Moreno S, Linard C, Adrait A, Cout xe9 Y, Peltzer J, et al. Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration. Stem Cell Res Ther. 2023;14:201 pubmed publisher
Zhang F, Wang Y, Zhao Y, Wang M, Zhou B, Ge X. NFATc1 marks articular cartilage progenitors and negatively determines articular chondrocyte differentiation. elife. 2023;12: pubmed publisher
Jakob L, M xfc ller T, Rassner M, Kleinfelder H, Veratti P, Mitschke J, et al. Murine Oncostatin M Has Opposing Effects on the Proliferation of OP9 Bone Marrow Stromal Cells and NIH/3T3 Fibroblasts Signaling through the OSMR. Int J Mol Sci. 2021;22: pubmed publisher
Xu Z, Lin C, Ho S, Vlad G, Suciu Foca N. Suppression of Experimental Autoimmune Encephalomyelitis by ILT3.Fc. J Immunol. 2021;206:554-565 pubmed publisher
Lin S, Huang C, Sun J, Bollt O, Wang X, Martine E, et al. The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma. EMBO Mol Med. 2019;11:e10849 pubmed publisher
Inagaki N, Inagaki F, Kokudo N, Miyajima A. Generation of mesothelial progenitor-like cells from mouse-induced pluripotent stem cells. FEBS Lett. 2019;593:386-394 pubmed publisher
Ogawa T, Li Y, Lua I, Hartner A, Asahina K. Isolation of a unique hepatic stellate cell population expressing integrin α8 from embryonic mouse livers. Dev Dyn. 2018;247:867-881 pubmed publisher
Wiencierz A, Kernbach M, Ecklebe J, Monnerat G, Tomiuk S, Raulf A, et al. Differential Expression Levels of Integrin Î±6 Enable the Selective Identification and Isolation of Atrial and Ventricular Cardiomyocytes. PLoS ONE. 2015;10:e0143538 pubmed publisher
Franke K, Vilne B, Prazeres da Costa O, Rudelius M, Peschel C, Oostendorp R, et al. In vivo hematopoietic Myc activation directs a transcriptional signature in endothelial cells within the bone marrow microenvironment. Oncotarget. 2015;6:21827-39 pubmed
Deward A, Cramer J, Lagasse E. Cellular heterogeneity in the mouse esophagus implicates the presence of a nonquiescent epithelial stem cell population. Cell Rep. 2014;9:701-11 pubmed publisher
Smith A, Lewis F, Aquila I, Waring C, Nocera A, Agosti V, et al. Isolation and characterization of resident endogenous c-Kit+ cardiac stem cells from the adult mouse and rat heart. Nat Protoc. 2014;9:1662-81 pubmed publisher
Chitteti B, Kobayashi M, Cheng Y, Zhang H, Poteat B, Broxmeyer H, et al. CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche. Blood. 2014;124:519-29 pubmed publisher
Kaanta A, Virtanen C, Selfors L, Brugge J, Neel B. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Res. 2013;15:R65 pubmed
Loffredo F, Steinhauser M, Gannon J, Lee R. Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair. Cell Stem Cell. 2011;8:389-98 pubmed publisher
Xu D, Fuster M, Lawrence R, Esko J. Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability. J Biol Chem. 2011;286:737-45 pubmed publisher
Asahina K, Tsai S, Li P, Ishii M, Maxson R, Sucov H, et al. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development. Hepatology. 2009;49:998-1011 pubmed publisher
Zimmerman A, Joosten B, Torensma R, Parnes J, van Leeuwen F, Figdor C. Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. Blood. 2006;107:3212-20 pubmed
Swart G, Lunter P, Kilsdonk J, Kempen L. Activated leukocyte cell adhesion molecule (ALCAM/CD166): signaling at the divide of melanoma cell clustering and cell migration?. Cancer Metastasis Rev. 2005;24:223-36 pubmed
van Kempen L, Nelissen J, Degen W, Torensma R, Weidle U, Bloemers H, et al. Molecular basis for the homophilic activated leukocyte cell adhesion molecule (ALCAM)-ALCAM interaction. J Biol Chem. 2001;276:25783-90 pubmed
Bowen M, Aruffo A, Bajorath J. Cell surface receptors and their ligands: in vitro analysis of CD6-CD166 interactions. Proteins. 2000;40:420-8 pubmed

product information

Product Type :

Antibody

Product Name :

CD166 (ALCAM) Monoclonal Antibody (eBioALC48), PE, eBioscience

Catalog # :

12-1661-82

Quantity :

100 ug

Price :

US 265.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.25 ug/test

Species :

Mouse

Clone :

eBioALC48

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.25 ug/test

Aliases :

activated leukocyte cell adhesion molecule; AI853494; ALCAM; BEN; CD166; CD166 antigen; cell adhesion molecule; DM-GRASP; FLJ38514; HB2; KG-CAM; MEMD; MGC71733; MuSC; Protein DM-GRASP; Protein MEMD; SB-10 antigen; SC1; unnamed protein product