CD147 Monoclonal Antibody (8D12), PE, eBioscience™ | Invitrogen 12-1472-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD147 Monoclonal Antibody (8D12), PE, eBioscience™

catalog :

12-1472-42

quantity :

100 Tests

price :

US 300

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

8D12

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 6a	Huang N, Pishesha N, Mukherjee J, Zhang S, Deshycka R, Sudaryo V, et al. Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin. Nat Commun. 2017;8:423 pubmed publisher
immunocytochemistry; human; loading ...; fig 3a	Marshall D, Harried S, Murphy J, Hall C, Shekhani M, Pain C, et al. Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins. Mol Ther. 2016;24:1760-1770 pubmed publisher
flow cytometry; human; 1:100; fig s10a	Zhu D, Wang Z, Zhao J, Calimeri T, Meng J, Hideshima T, et al. The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nat Med. 2015;21:572-80 pubmed publisher
	de Back D, Nezjad S, Beuger B, Veldhuis M, Clifford E, Ait Ichou F, et al. Apheresis causes complement deposition on red blood cells (RBCs) and RBC antigen alterations, possibly inducing enhanced clearance. Transfusion. 2018;58:2627-2634 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD147 Monoclonal Antibody (8D12), PE, eBioscience™

Catalog # :

12-1472-42

Quantity :

100 Tests

Price :

US 300

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.25 µg)/test

Species :

Human

Clone :

8D12

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.25 µg)/test

Aliases :

5A11; 5A11/Basigin; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Bsg; CD147; CE9; collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HT7; HT-7; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; TCSF; Tumor cell-derived collagenase stimulatory factor; UNQ6505/PRO21383

more info or order :

Invitrogen product webpage