CD147 Monoclonal Antibody (RL73), PE, eBioscience™ | Invitrogen 12-1471-81 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD147 Monoclonal Antibody (RL73), PE, eBioscience™

catalog :

12-1471-81

quantity :

50 µg

price :

US 140

clonality :

monoclonal

host :

rat

conjugate :

clone name :

RL73

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 3c	Patrizz A, Doran S, Chauhan A, Ahnstedt H, Roy O Reilly M, Lai Y, et al. EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke. Aging (Albany NY). 2020;12:5121-5139 pubmed publisher
flow cytometry; mouse; loading ...; fig s4b	Byrne S, Ortiz L, Mali P, Aach J, Church G. Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells. Nucleic Acids Res. 2015;43:e21 pubmed publisher
	Dey S, Eisa A, Kline D, Wagner F, Abeysirigunawardena S, Vijayaraghavan S. Roles of glycogen synthase kinase 3 alpha and calcineurin in regulating the ability of sperm to fertilize eggs. FASEB J. 2020;34:1247-1269 pubmed publisher
	Liu H, Yang L, Guo R, Zhu G, Shi Y, Wang X, et al. Functional blockage of EMMPRIN ameliorates atherosclerosis in apolipoprotein E-deficient mice. Int J Cardiol. 2013;168:3248-53 pubmed publisher
	Kasler H, Lim H, Mottet D, Collins A, Lee I, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. EMBO J. 2012;31:4453-65 pubmed publisher
	Agrawal S, Silva C, Wang J, Tong J, Yong V. A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis. J Neuroinflammation. 2012;9:64 pubmed publisher
	Kasler H, Young B, Mottet D, Lim H, Collins A, Olson E, et al. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. J Immunol. 2011;186:4782-93 pubmed publisher
	Treese C, Mittag A, Lange F, Tarnok A, Loesche A, Emmrich F, et al. Characterization of fibroblasts responsible for cartilage destruction in arthritis. Cytometry A. 2008;73:351-60 pubmed publisher
	Renno T, Wilson A, Dunkel C, Coste I, Maisnier Patin K, Benoit de Coignac A, et al. A role for CD147 in thymic development. J Immunol. 2002;168:4946-50 pubmed
	Coste I, Gauchat J, Wilson A, Izui S, Jeannin P, Delneste Y, et al. Unavailability of CD147 leads to selective erythrocyte trapping in the spleen. Blood. 2001;97:3984-8 pubmed
	MacDonald H, Lees R, Bron C. Cell surface glycoproteins involved in the stimulation of interleukin 1-dependent interleukin 2 production by a subline of EL4 thymoma cells. I. Functional characterization by monoclonal antibodies. J Immunol. 1985;135:3944-50 pubmed

product information

Product Type :

Antibody

Product Name :

CD147 Monoclonal Antibody (RL73), PE, eBioscience™

Catalog # :

12-1471-81

Quantity :

50 µg

Price :

US 140

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.125 µg/test

Species :

Mouse

Clone :

RL73

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.125 µg/test

Aliases :

5A11; 5A11/Basigin; 5F7; AI115436; AI325119; Basic immunoglobulin superfamily; basigin; basigin (Ok blood group); Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); basignin; Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian); Bsg; CD147; CE9; collagenase stimulatory factor; EMMPRIN; Extracellular matrix metalloproteinase inducer; Glycoprotein CE9; gp 42; HT7; HT-7; HT7 antigen; Leukocyte activation antigen M6; Membrane glycoprotein gp42; neurothelin; OK; OK blood group antigen; OX-47 antigen; Ox47R; TCSF; Tumor cell-derived collagenase stimulatory factor; UNQ6505/PRO21383

more info or order :

Invitrogen product webpage