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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD144 (VE-cadherin) Monoclonal Antibody (eBioBV13 (BV13)), PE, eBioscience™
catalog :
12-1441-82
quantity :
100 µg
price :
US 401
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
eBioBV13 (BV13)
reactivity :
mouse
application :
immunocytochemistry, flow cytometry
more info or order :
Invitrogen product webpage
citations: 37
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:50; fig 2
  • immunocytochemistry; mouse; 1:50; fig 1
Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher
Zhang L, He J, Wang J, Liu J, Chen Z, Deng B, et al. Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy. Cell Death Dis. 2021;12:470 pubmed publisher
Fu H, Sun Y, Shao Y, Saredy J, Cueto R, Liu L, et al. Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis. Front Immunol. 2020;11:595813 pubmed publisher
Park J, Lee T, Do E, Moon H, Kim J. Role of Notch1 in the arterial specification and angiogenic potential of mouse embryonic stem cell-derived endothelial cells. Stem Cell Res Ther. 2018;9:197 pubmed publisher
Baron C, Kester L, Klaus A, Boisset J, Thambyrajah R, Yvernogeau L, et al. Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta. Nat Commun. 2018;9:2517 pubmed publisher
Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher
Wang S, Chennupati R, Kaur H, Iring A, Wettschureck N, Offermanns S. Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release. J Clin Invest. 2016;126:4527-4536 pubmed publisher
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed publisher
Phoenix T, Patmore D, Boop S, Boulos N, Jacus M, Patel Y, et al. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. Cancer Cell. 2016;29:508-522 pubmed publisher
Vargel O, Zhang Y, Kosim K, Ganter K, Foehr S, Mardenborough Y, et al. Activation of the TGFβ pathway impairs endothelial to haematopoietic transition. Sci Rep. 2016;6:21518 pubmed publisher
Behrens A, Zierold C, Shi X, Ren Y, Koyano Nakagawa N, Garry D, et al. Sox7 is regulated by ETV2 during cardiovascular development. Stem Cells Dev. 2014;23:2004-13 pubmed publisher
Sung N, Yang M, Song D, Byun E, Kim J, Park J, et al. The procyanidin trimer C1 induces macrophage activation via NF-?B and MAPK pathways, leading to Th1 polarization in murine splenocytes. Eur J Pharmacol. 2013;714:218-28 pubmed publisher
Flavahan S, Mozayan M, Lindgren I, Flavahan N. Pressure-induced maturation of endothelial cells on newborn mouse carotid arteries. Am J Physiol Heart Circ Physiol. 2013;305:H321-9 pubmed publisher
Clarke R, Yzaguirre A, Yashiro Ohtani Y, Bondue A, Blanpain C, Pear W, et al. The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol. 2013;15:502-10 pubmed publisher
Rapraeger A, Ell B, Roy M, Li X, Morrison O, Thomas G, et al. Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between ?V?3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesi. FEBS J. 2013;280:2194-206 pubmed publisher
Joo H, Choi D, Lim J, Park J, Lee S, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood. 2012;120:2733-44 pubmed
Gasparetto M, Sekulovic S, Zakaryan A, Imren S, Kent D, Humphries R, et al. Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status. Exp Hematol. 2012;40:857-66.e5 pubmed publisher
Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, et al. GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment. Blood. 2012;120:314-22 pubmed publisher
Mirza M, Pang M, Zaini M, Haiko P, Tammela T, Alitalo K, et al. Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice. PLoS ONE. 2012;7:e37523 pubmed publisher
Dasgupta S, Le A, Chavakis T, Rumbaut R, Thiagarajan P. Developmental endothelial locus-1 (Del-1) mediates clearance of platelet microparticles by the endothelium. Circulation. 2012;125:1664-72 pubmed publisher
Liu F, Kang I, Park C, Chang L, Wang W, Lee D, et al. ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling. Blood. 2012;119:3295-305 pubmed publisher
Song K, Kwon K, Song S, Suh K, Doh J. Dynamics of T cells on endothelial layers aligned by nanostructured surfaces. Biomaterials. 2012;33:2007-15 pubmed publisher
Mihira H, Suzuki H, Akatsu Y, Yoshimatsu Y, Igarashi T, Miyazono K, et al. TGF-?-induced mesenchymal transition of MS-1 endothelial cells requires Smad-dependent cooperative activation of Rho signals and MRTF-A. J Biochem. 2012;151:145-56 pubmed publisher
O Dea K, Dokpesi J, Tatham K, Wilson M, Takata M. Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway. Am J Physiol Lung Cell Mol Physiol. 2011;301:L812-21 pubmed publisher
Gill J, Langer E, Lindsley R, Cai M, Murphy T, Murphy K. Snail promotes the cell-autonomous generation of Flk1(+) endothelial cells through the repression of the microRNA-200 family. Stem Cells Dev. 2012;21:167-76 pubmed publisher
Joo H, Kim H, Park S, Cho H, Kim H, Lim D, et al. Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells. Blood. 2011;118:2094-104 pubmed publisher
Langer H, Orlova V, Xie C, Kaul S, Schneider D, Lonsdorf A, et al. A novel function of junctional adhesion molecule-C in mediating melanoma cell metastasis. Cancer Res. 2011;71:4096-105 pubmed publisher
Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, et al. Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med. 2011;208:949-60 pubmed publisher
Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson T, et al. ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification. Genes Dev. 2011;25:251-62 pubmed publisher
Yokomizo T, Dzierzak E. Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010;137:3651-61 pubmed publisher
Gossens K, Naus S, Hollander G, Ziltener H. Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity. PLoS ONE. 2010;5:e12766 pubmed publisher
Sumagin R, Sarelius I. Intercellular adhesion molecule-1 enrichment near tricellular endothelial junctions is preferentially associated with leukocyte transmigration and signals for reorganization of these junctions to accommodate leukocyte passage. J Immunol. 2010;184:5242-52 pubmed publisher
Kajimoto K, Hossen M, Hida K, Ohga N, Akita H, Hyodo M, et al. Isolation and culture of microvascular endothelial cells from murine inguinal and epididymal adipose tissues. J Immunol Methods. 2010;357:43-50 pubmed publisher
Lu K, Lamagna C, Bergers G. Chapter 3. Bone marrow-derived vascular progenitors and proangiogenic monocytes in tumors. Methods Enzymol. 2008;445:53-82 pubmed publisher
Crosby C, Fleming P, Argraves W, Corada M, Zanetta L, Dejana E, et al. VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly. Blood. 2005;105:2771-6 pubmed
Liao F, Li Y, O Connor W, Zanetta L, Bassi R, Santiago A, et al. Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis. Cancer Res. 2000;60:6805-10 pubmed
Corada M, Mariotti M, Thurston G, Smith K, Kunkel R, Brockhaus M, et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A. 1999;96:9815-20 pubmed
product information
Product Type :
Antibody
Product Name :
CD144 (VE-cadherin) Monoclonal Antibody (eBioBV13 (BV13)), PE, eBioscience™
Catalog # :
12-1441-82
Quantity :
100 µg
Price :
US 401
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.25 µg/test
Species :
Mouse
Clone :
eBioBV13 (BV13)
Isotype :
IgG1, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
VE-cadherin is a member of the cadherin superfamily that is located in a six-cadherin cluster in a region on the long arm of chromosome 16 and is involved in loss of heterozygosity events in breast and prostate cancer. VE-cadherin protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, VE-cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but the full length sequence of VE-cadherin has not been determined.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.25 µg/test
Aliases :
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; CD144; cd144 antigen; Cdh5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA