product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CD140a (PDGFRA) Monoclonal Antibody (APA5), PE, eBioscience™
catalog :
12-1401-81
quantity :
50 µg
price :
US 208
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
APA5
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 113
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:500; fig 4b
Minakawa T, Matoba T, Ishidate F, Fujiwara T, Takehana S, Tabata Y, et al. Extracellular vesicles synchronize cellular phenotypes of differentiating cells. J Extracell Vesicles. 2021;10:e12147 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 1s3a
Hemanthakumar K, Fang S, Anisimov A, Mäyränpää M, Mervaala E, Kivela R. Cardiovascular disease risk factors induce mesenchymal features and senescence in mouse cardiac endothelial cells. elife. 2021;10: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Sanmarco L, Wheeler M, Gutiérrez Vázquez C, Polonio C, Linnerbauer M, Pinho Ribeiro F, et al. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes. Nature. 2021;: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3d
Garcia Agudo L, Janova H, Sendler L, Arinrad S, Steixner A, Hassouna I, et al. Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion. FASEB J. 2019;33:8634-8647 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 5s1c
Walens A, DiMarco A, Lupo R, Kroger B, Damrauer J, Alvarez J. CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Feng Y, Liao Y, Huang W, Lai X, Luo J, Du C, et al. Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis. Cell Death Dis. 2018;9:691 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4e
Chang S, Kohlgruber A, Mizoguchi F, Michelet X, Wolf B, Wei K, et al. Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes. J Clin Invest. 2017;127:3300-3312 pubmed publisher
  • flow cytometry; mouse; 1:30; loading ...
Lukjanenko L, Jung M, Hegde N, Perruisseau Carrier C, Migliavacca E, Rozo M, et al. Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice. Nat Med. 2016;22:897-905 pubmed publisher
  • flow cytometry; mouse; 1:75; loading ...; fig 1l
Chiapparo G, Lin X, Lescroart F, Chabab S, Paulissen C, Pitisci L, et al. Mesp1 controls the speed, polarity, and directionality of cardiovascular progenitor migration. J Cell Biol. 2016;213:463-77 pubmed publisher
  • flow cytometry; mouse; fig 3e
Ziętara N, Łyszkiewicz M, Puchałka J, Witzlau K, Reinhardt A, Förster R, et al. Multicongenic fate mapping quantification of dynamics of thymus colonization. J Exp Med. 2015;212:1589-601 pubmed publisher
  • flow cytometry; mouse; tbl 2
Yanagida A, Chikada H, Ito K, Umino A, Kato Itoh M, Yamazaki Y, et al. Liver maturation deficiency in p57(Kip2)-/- mice occurs in a hepatocytic p57(Kip2) expression-independent manner. Dev Biol. 2015;407:331-43 pubmed publisher
  • flow cytometry; mouse; fig 3
Sohn J, Lu A, Tang Y, Wang B, Huard J. Activation of non-myogenic mesenchymal stem cells during the disease progression in dystrophic dystrophin/utrophin knockout mice. Hum Mol Genet. 2015;24:3814-29 pubmed publisher
Dada L, Welch L, Magnani N, Ren Z, Han H, Brazee P, et al. Hypercapnia alters stroma-derived Wnt production to limit β-catenin signaling and proliferation in AT2 cells. JCI Insight. 2023;8: pubmed publisher
Geng Y, Li L, Yan J, Liu K, Yang A, Zhang L, et al. PEAR1 regulates expansion of activated fibroblasts and deposition of extracellular matrix in pulmonary fibrosis. Nat Commun. 2022;13:7114 pubmed publisher
Kanazawa S, Okada H, Riu D, Mabuchi Y, Akazawa C, Iwata J, et al. Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells. Int J Mol Sci. 2022;23: pubmed publisher
Potluri T, Taylor M, Stulberg J, Lieber R, Zhao H, Bulun S. An estrogen-sensitive fibroblast population drives abdominal muscle fibrosis in an inguinal hernia mouse model. JCI Insight. 2022;7: pubmed publisher
Jarmas A, Brunskill E, Chaturvedi P, Salomonis N, Kopan R. Progenitor translatome changes coordinated by Tsc1 increase perception of Wnt signals to end nephrogenesis. Nat Commun. 2021;12:6332 pubmed publisher
Westcott G, Emont M, Li J, Jacobs C, Tsai L, Rosen E. Mesothelial cells are not a source of adipocytes in mice. Cell Rep. 2021;36:109388 pubmed publisher
Nishina T, Deguchi Y, Ohshima D, Takeda W, Ohtsuka M, Shichino S, et al. Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer. Nat Commun. 2021;12:2281 pubmed publisher
He H, Snowball J, Sun F, Na C, Whitsett J. IGF1R controls mechanosignaling in myofibroblasts required for pulmonary alveologenesis. JCI Insight. 2021;6: pubmed publisher
Ma S, McGuire M, Mangala L, Lee S, Stur E, Hu W, et al. Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. Cell Rep. 2021;34:108726 pubmed publisher
Hussain A, Deleuze V, El Kebriti L, Turali H, Pirot N, Glasson Y, et al. In Lyl1-/- mice, adipose stem cell vascular niche impairment leads to premature development of fat tissues. Stem Cells. 2021;39:78-91 pubmed publisher
Redente E, Chakraborty S, Sajuthi S, Black B, Edelman B, Seibold M, et al. Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis. JCI Insight. 2020;6: pubmed publisher
Wu R, Ma F, Tosevska A, Farrell C, Pellegrini M, Deb A. Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age. JCI Insight. 2020;5: pubmed publisher
Jiang M, Ye J, Wang X, Li N, Wang Y, Shi Y. Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals. Cell Biosci. 2020;10:65 pubmed publisher
Wang S, Cao S, Arhatte M, Li D, Shi Y, Kurz S, et al. Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. Nat Commun. 2020;11:2303 pubmed publisher
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
Li R, Li X, Hagood J, Zhu M, Sun X. Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface. J Clin Invest. 2020;130:2859-2871 pubmed publisher
McCarthy N, Manieri E, Storm E, Saadatpour A, Luoma A, Kapoor V, et al. Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient. Cell Stem Cell. 2020;: pubmed publisher
Wheeler M, Clark I, Tjon E, Li Z, Zandee S, Couturier C, et al. MAFG-driven astrocytes promote CNS inflammation. Nature. 2020;578:593-599 pubmed publisher
Tournaire G, Stegen S, Giacomini G, Stockmans I, Moermans K, Carmeliet G, et al. Nestin-GFP transgene labels skeletal progenitors in the periosteum. Bone. 2020;133:115259 pubmed publisher
Santini M, Malide D, Hoffman G, Pandey G, D Escamard V, Nomura Kitabayashi A, et al. Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner. Cell Rep. 2020;30:555-570.e7 pubmed publisher
Dokoshi T, Zhang L, Li F, Nakatsuji T, Butcher A, Yoshida H, et al. Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection. Cell Rep. 2020;30:61-68.e4 pubmed publisher
Naipauer J, Rosario S, Gupta S, Premer C, Méndez Solís O, Schlesinger M, et al. PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment. PLoS Pathog. 2019;15:e1008221 pubmed publisher
Chao C, Gutiérrez Vázquez C, Rothhammer V, Mayo L, Wheeler M, Tjon E, et al. Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. 2019;179:1483-1498.e22 pubmed publisher
Ershaid N, Sharon Y, Doron H, Raz Y, Shani O, Cohen N, et al. NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis. Nat Commun. 2019;10:4375 pubmed publisher
Alexander J, Guan J, Li B, Maliskova L, Song M, Shen Y, et al. Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity. elife. 2019;8: pubmed publisher
Huang X, Feng T, Jiang Z, Meng J, Kou S, Lu Z, et al. Dual lineage tracing identifies intermediate mesenchymal stage for endocardial contribution to fibroblasts, coronary mural cells, and adipocytes. J Biol Chem. 2019;294:8894-8906 pubmed publisher
Camps J, Grosemans H, Gijsbers R, Maes C, Sampaolesi M. Growth Factor Screening in Dystrophic Muscles Reveals PDGFB/PDGFRB-Mediated Migration of Interstitial Stem Cells. Int J Mol Sci. 2019;20: pubmed publisher
Chagraoui H, Kristiansen M, Ruiz J, Serra Barros A, Richter J, Hall Ponsele E, et al. SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells. Nat Commun. 2018;9:5375 pubmed publisher
Chaudhury S, O Connor C, Cañete A, Bittencourt Silvestre J, Sarrou E, Prendergast Á, et al. Age-specific biological and molecular profiling distinguishes paediatric from adult acute myeloid leukaemias. Nat Commun. 2018;9:5280 pubmed publisher
Raz Y, Cohen N, Shani O, Bell R, Novitskiy S, Abramovitz L, et al. Bone marrow-derived fibroblasts are a functionally distinct stromal cell population in breast cancer. J Exp Med. 2018;215:3075-3093 pubmed publisher
Li R, Bernau K, Sandbo N, Gu J, Preissl S, Sun X. Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response. elife. 2018;7: pubmed publisher
Dammone G, Karaz S, Lukjanenko L, Winkler C, Sizzano F, Jacot G, et al. PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration. Int J Mol Sci. 2018;19: pubmed publisher
Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher
Wuidart A, Sifrim A, Fioramonti M, Matsumura S, Brisebarre A, Brown D, et al. Early lineage segregation of multipotent embryonic mammary gland progenitors. Nat Cell Biol. 2018;20:666-676 pubmed publisher
Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, et al. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018;24:782-791 pubmed publisher
Roswall P, Bocci M, Bartoschek M, Li H, Kristiansen G, Jansson S, et al. Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling. Nat Med. 2018;24:463-473 pubmed publisher
Yoon C, Song H, Yin T, Bausch Fluck D, Frei A, Kattman S, et al. FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors. Stem Cell Reports. 2018;10:87-100 pubmed publisher
Shi Y, He G, Lee W, McKenzie J, Silva M, Long F. Gli1 identifies osteogenic progenitors for bone formation and fracture repair. Nat Commun. 2017;8:2043 pubmed publisher
Anderson K, Hamilton W, Roske F, Azad A, Knudsen T, Canham M, et al. Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm. Nat Cell Biol. 2017;19:1164-1177 pubmed publisher
Donovan P, Dubey O, Kallioinen S, Rogers K, Muehlethaler K, Muller P, et al. Paracrine Activin-A Signaling Promotes Melanoma Growth and Metastasis through Immune Evasion. J Invest Dermatol. 2017;137:2578-2587 pubmed publisher
Bosnakovski D, Gearhart M, Toso E, Recht O, Cucak A, Jain A, et al. p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy. Dis Model Mech. 2017;10:1211-1216 pubmed publisher
Ambrosi T, Scialdone A, Graja A, Gohlke S, Jank A, Bocian C, et al. Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration. Cell Stem Cell. 2017;20:771-784.e6 pubmed publisher
Agarwal S, Cholok D, Loder S, Li J, Breuler C, Chung M, et al. mTOR inhibition and BMP signaling act synergistically to reduce muscle fibrosis and improve myofiber regeneration. JCI Insight. 2016;1:e89805 pubmed publisher
Topalovski M, Hagopian M, Wang M, Brekken R. Hypoxia and Transforming Growth Factor ? Cooperate to Induce Fibulin-5 Expression in Pancreatic Cancer. J Biol Chem. 2016;291:22244-22252 pubmed
Williams C, Fernández Alonso R, Wang J, Toth R, Gray N, Findlay G. Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity. Cell Rep. 2016;16:1820-8 pubmed publisher
Kanisicak O, Khalil H, Ivey M, Karch J, Maliken B, Correll R, et al. Genetic lineage tracing defines myofibroblast origin and function in the injured heart. Nat Commun. 2016;7:12260 pubmed publisher
Wuidart A, Ousset M, Rulands S, Simons B, Van Keymeulen A, Blanpain C. Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells. Genes Dev. 2016;30:1261-77 pubmed publisher
Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
Pallangyo C, Ziegler P, Greten F. IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis. J Exp Med. 2015;212:2253-66 pubmed publisher
Quattrocelli M, Swinnen M, Giacomazzi G, Camps J, Barthélemy I, Ceccarelli G, et al. Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. J Clin Invest. 2015;125:4463-82 pubmed publisher
Caputo L, Witzel H, Kolovos P, Cheedipudi S, Looso M, Mylona A, et al. The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors. Cell Stem Cell. 2015;17:287-99 pubmed publisher
Djelloul M, Holmqvist S, Boza Serrano A, Azevedo C, Yeung M, Goldwurm S, et al. Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models. Stem Cell Reports. 2015;5:174-84 pubmed publisher
Najm F, Madhavan M, Zaremba A, Shick E, Karl R, Factor D, et al. Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature. 2015;522:216-20 pubmed publisher
Alexander J, Hota S, He D, Thomas S, Ho L, Pennacchio L, et al. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development. 2015;142:1418-30 pubmed publisher
Qin Y, Qin J, Zhou C, Li J, Gao W. Generation of embryonic stem cells from mouse adipose-tissue derived cells via somatic cell nuclear transfer. Cell Cycle. 2015;14:1282-90 pubmed publisher
Cambuli F, Murray A, Dean W, Dudzińska D, Krueger F, Andrews S, et al. Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast. Nat Commun. 2014;5:5538 pubmed publisher
Kimura Y, Komaki M, Iwasaki K, Sata M, Izumi Y, Morita I. Recruitment of bone marrow-derived cells to periodontal tissue defects. Front Cell Dev Biol. 2014;2:19 pubmed publisher
Zhang M, Zhou H, Zheng C, Xiao J, Zuo E, Liu W, et al. The roles of testicular c-kit positive cells in de novo morphogenesis of testis. Sci Rep. 2014;4:5936 pubmed publisher
Donati G, Proserpio V, Lichtenberger B, Natsuga K, Sinclair R, Fujiwara H, et al. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors. Proc Natl Acad Sci U S A. 2014;111:E1501-9 pubmed publisher
Furtado M, Costa M, Pranoto E, Salimova E, Pinto A, Lam N, et al. Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair. Circ Res. 2014;114:1422-34 pubmed publisher
Osada M, Singh V, Wu K, Sant Angelo D, Pezzano M. Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus. PLoS ONE. 2013;8:e83024 pubmed publisher
Nakatsuka R, Matsuoka Y, Uemura Y, Sumide K, Iwaki R, Takahashi M, et al. Mouse dental pulp stem cells support human umbilical cord blood-derived hematopoietic stem/progenitor cells in vitro. Cell Transplant. 2015;24:97-113 pubmed publisher
Qin Y, Zhou P, Zhou C, Li J, Gao W. The adipose-derived lineage-negative cells are enriched mesenchymal stem cells and promote limb ischemia recovery in mice. Stem Cells Dev. 2014;23:363-71 pubmed publisher
Aslam M, Hettmer S, Abraham J, LaTocha D, Soundararajan A, Huang E, et al. Dynamic and nuclear expression of PDGFR? and IGF-1R in alveolar Rhabdomyosarcoma. Mol Cancer Res. 2013;11:1303-13 pubmed publisher
Morgani S, Canham M, Nichols J, Sharov A, Migueles R, Ko M, et al. Totipotent embryonic stem cells arise in ground-state culture conditions. Cell Rep. 2013;3:1945-57 pubmed publisher
Buono K, Vadlamuri D, Gan Q, Levison S. Leukemia inhibitory factor is essential for subventricular zone neural stem cell and progenitor homeostasis as revealed by a novel flow cytometric analysis. Dev Neurosci. 2012;34:449-62 pubmed publisher
Lapouge G, Beck B, Nassar D, Dubois C, Dekoninck S, Blanpain C. Skin squamous cell carcinoma propagating cells increase with tumour progression and invasiveness. EMBO J. 2012;31:4563-75 pubmed publisher
Seach N, Wong K, Hammett M, Boyd R, Chidgey A. Purified enzymes improve isolation and characterization of the adult thymic epithelium. J Immunol Methods. 2012;385:23-34 pubmed publisher
Joo H, Choi D, Lim J, Park J, Lee S, Song S, et al. ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell-derived Flk1(+) mesodermal precursor cells. Blood. 2012;120:2733-44 pubmed
Hashitani H, Mitsui R, Shimizu Y, Higashi R, Nakamura K. Functional and morphological properties of pericytes in suburothelial venules of the mouse bladder. Br J Pharmacol. 2012;167:1723-36 pubmed publisher
Koyano Nakagawa N, Kweon J, Iacovino M, Shi X, Rasmussen T, Borges L, et al. Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression. Stem Cells. 2012;30:1611-23 pubmed publisher
van den Ameele J, Tiberi L, Bondue A, Paulissen C, Herpoel A, Iacovino M, et al. Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin. EMBO Rep. 2012;13:355-62 pubmed publisher
Liu F, Kang I, Park C, Chang L, Wang W, Lee D, et al. ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling. Blood. 2012;119:3295-305 pubmed publisher
Nakamura Ishizu A, Kurihara T, Okuno Y, Ozawa Y, Kishi K, Goda N, et al. The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner. Dev Biol. 2012;363:106-14 pubmed publisher
Rasmussen T, Kweon J, Diekmann M, Belema Bedada F, Song Q, Bowlin K, et al. ER71 directs mesodermal fate decisions during embryogenesis. Development. 2011;138:4801-12 pubmed publisher
Gill J, Langer E, Lindsley R, Cai M, Murphy T, Murphy K. Snail promotes the cell-autonomous generation of Flk1(+) endothelial cells through the repression of the microRNA-200 family. Stem Cells Dev. 2012;21:167-76 pubmed publisher
Kubota Y, Takubo K, Hirashima M, Nagoshi N, Kishi K, Okuno Y, et al. Isolation and function of mouse tissue resident vascular precursors marked by myelin protein zero. J Exp Med. 2011;208:949-60 pubmed publisher
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Groneberg D, Konig P, Koesling D, Friebe A. Nitric oxide-sensitive guanylyl cyclase is dispensable for nitrergic signaling and gut motility in mouse intestinal smooth muscle. Gastroenterology. 2011;140:1608-17 pubmed publisher
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LaMarca H, Visbal A, Creighton C, Liu H, Zhang Y, Behbod F, et al. CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells. 2010;28:535-44 pubmed publisher
Iino S, Nojyo Y. Immunohistochemical demonstration of c-Kit-negative fibroblast-like cells in murine gastrointestinal musculature. Arch Histol Cytol. 2009;72:107-15 pubmed
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Sher F, van Dam G, Boddeke E, Copray S. Bioluminescence imaging of Olig2-neural stem cells reveals improved engraftment in a demyelination mouse model. Stem Cells. 2009;27:1582-91 pubmed publisher
Iino S, Horiguchi K, Horiguchi S, Nojyo Y. c-Kit-negative fibroblast-like cells express platelet-derived growth factor receptor alpha in the murine gastrointestinal musculature. Histochem Cell Biol. 2009;131:691-702 pubmed publisher
Odaka C. Localization of mesenchymal cells in adult mouse thymus: their abnormal distribution in mice with disorganization of thymic medullary epithelium. J Histochem Cytochem. 2009;57:373-82 pubmed publisher
Kubota Y, Hirashima M, Kishi K, Stewart C, Suda T. Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice. J Clin Invest. 2008;118:2393-403 pubmed publisher
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Sherwood R, Jitianu C, Cleaver O, Shaywitz D, Lamenzo J, Chen A, et al. Prospective isolation and global gene expression analysis of definitive and visceral endoderm. Dev Biol. 2007;304:541-55 pubmed
Mukouyama Y, Deneen B, Lukaszewicz A, Novitch B, Wichterle H, Jessell T, et al. Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A. 2006;103:1551-6 pubmed
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Kaplan R, Riba R, Zacharoulis S, Bramley A, Vincent L, Costa C, et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature. 2005;438:820-7 pubmed
Harman B, Jenkinson W, Parnell S, Rossi S, Jenkinson E, Anderson G. T/B lineage choice occurs prior to intrathymic Notch signaling. Blood. 2005;106:886-92 pubmed
Miyawaki T, Uemura A, Dezawa M, Yu R, Ide C, Nishikawa S, et al. Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina. J Neurosci. 2004;24:8124-34 pubmed
Takakura N, Yoshida H, Ogura Y, Kataoka H, Nishikawa S. PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5. J Histochem Cytochem. 1997;45:883-93 pubmed
product information
Product Type :
Antibody
Product Name :
CD140a (PDGFRA) Monoclonal Antibody (APA5), PE, eBioscience™
Catalog # :
12-1401-81
Quantity :
50 µg
Price :
US 208
Clonality :
Monoclonal
Purity :
Affinity chromatography
Host :
Rat
Reactivity :
Mouse
Applications :
Flow Cytometry: 0.5 µg/test
Species :
Mouse
Clone :
APA5
Isotype :
IgG2a, kappa
Storage :
4° C, store in dark, DO NOT FREEZE!
Description :
PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 0.5 µg/test
Aliases :
AI115593; Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140a; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA