CD138 (Syndecan-1) Monoclonal Antibody (DL-101), PE, eBioscience™ | Invitrogen 12-1389-42 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD138 (Syndecan-1) Monoclonal Antibody (DL-101), PE, eBioscience™

catalog :

12-1389-42

quantity :

100 Tests

price :

US 309

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

DL-101

reactivity :

human

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 8a	Liu J, Huang X, Hao S, Wang Y, Liu M, Xu J, et al. Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus. Nat Commun. 2018;9:1136 pubmed publisher
flow cytometry; human; 1:100; fig 7	Brown P, Gascoyne D, Lyne L, Spearman H, Felce S, McFadden N, et al. N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells. Haematologica. 2016;101:861-71 pubmed publisher
	Akidil E, Albanese M, Buschle A, Ruhle A, Pich D, Keppler O, et al. Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection. PLoS Pathog. 2021;17:e1009117 pubmed publisher
	Castro Dopico T, Dennison T, Ferdinand J, Mathews R, FLEMING A, Clift D, et al. Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis. Immunity. 2019;50:1099-1114.e10 pubmed publisher
	Ibrahim S, Gadalla R, El Ghonaimy E, Samir O, Mohamed H, Hassan H, et al. Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways. Mol Cancer. 2017;16:57 pubmed publisher
	Schibler J, Tomanek Chalkley A, Reedy J, Zhan F, Spitz D, Schultz M, et al. Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells. PLoS ONE. 2016;11:e0167323 pubmed publisher
	Martinez Murillo P, Pramanik L, Sundling C, Hultenby K, Wretenberg P, Spångberg M, et al. CD138 and CD31 Double-Positive Cells Comprise the Functional Antibody-Secreting Plasma Cell Compartment in Primate Bone Marrow. Front Immunol. 2016;7:242 pubmed publisher
	Montezuma Rusca J, Moir S, Kardava L, Buckner C, Louie A, Kim L, et al. Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals. J Immunol. 2015;194:2561-8 pubmed publisher
	Wang D, Feng X, Lu L, Konkel J, Zhang H, Chen Z, et al. A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus. Arthritis Rheumatol. 2014;66:2234-45 pubmed publisher
	Itoua Maïga R, Lemieux J, Roy A, Simard C, Néron S. Flow cytometry assessment of in vitro generated CD138+ human plasma cells. Biomed Res Int. 2014;2014:536482 pubmed publisher
	Demberg T, Brocca Cofano E, Xiao P, Venzon D, Vargas Inchaustegui D, Lee E, et al. Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques. J Virol. 2012;86:12591-604 pubmed publisher
	Mesin L, Di Niro R, Thompson K, Lundin K, Sollid L. Long-lived plasma cells from human small intestine biopsies secrete immunoglobulins for many weeks in vitro. J Immunol. 2011;187:2867-74 pubmed publisher
	Cantor J, Browne C, Ruppert R, Feral C, Fassler R, Rickert R, et al. CD98hc facilitates B cell proliferation and adaptive humoral immunity. Nat Immunol. 2009;10:412-9 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD138 (Syndecan-1) Monoclonal Antibody (DL-101), PE, eBioscience™

Catalog # :

12-1389-42

Quantity :

100 Tests

Price :

US 309

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 µL (0.5 µg)/test

Species :

Human

Clone :

DL-101

Isotype :

IgG1, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL (0.5 µg)/test

Aliases :

AA408134; AA409076; CD antigen 138; CD138; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; HSPG; sCD138; SDC; Sdc1; soluble CD138; Sstn; syn-1; Synd; SYND1; Synd-1; SYNDECA; Syndecan; syndecan 1; syndecan proteoglycan 1; Syndecan1; syndecan-1; synstatin

more info or order :

Invitrogen product webpage